ISSN:
1399-0047
Source:
Crystallography Journals Online : IUCR Backfile Archive 1948-2001
Topics:
Chemistry and Pharmacology
,
Geosciences
,
Physics
Notes:
The vacuolar aspartic proteinase from baker's yeast, saccharopepsin, has been co-crystallized with its natural inhibitor IA3, found in the cytosol. The IA3–saccharopepsin complex crystals belong to the space group P6222, with unit-cell parameters a = b = 192.1, c = 59.80 Å and one molecule per asymmetric unit. The initial X-ray analysis of the complex indicates that the crystals diffract to 5.0 Å, similar to native saccharopepsin crystals. This is probably a consequence in part of glycosylation of the native saccharopepsin. Full structural analysis of the complex crystal is in progress.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1107/S090744490000737X
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