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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 46 (1968), S. 1317-1318 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary 1. The separate determination of ketone bodies, glucose and glycerol in umbilical cord artery and vein, placental artery and vein resulted in elevated levels of glycerol and ketone bodies in placental blood compared to cord blood. 2. It is concluded that for experimental purposes cord blood is not to be replaced by placental blood. 3. In analysing the possible facts we drew the conclusion that these results indicate a representation of the placental metabolism. Hemodynamic factors were not to be excluded, however. 4. The comparison of placental with cord blood under normal and pathological conditions will possibly add to the study of placental metabolism in situ.
    Notes: Zusammenfassung 1. Die Bestimmung von Ketonkörpern, Glucose und Glycerin getrennt in Nabelartcrie, Nabelvene, Placentararterie und Placentarvene ergab für Glycerin und Ketonkörper im Placentarblut meist etwas höhere Werte als im Nabelschnurblut. 2. Es folgt daraus, daß es nicht zulässig ist, aus experimentellen Gründen Placentarblut an Stelle von Nabelschnurblut zu verwenden. 3. Durch die Analyse der möglichen Ursachen kamen wir zu dem Schluß, daß es sich bei diesen Veränderungen wahrscheinlich um eine Widerspiegelung des placentaren Stoffwechsels handelt. Hämodynamische Einflüsse jedoch sind nicht auszuschließen. 4. Es ist möglich, daß der Vergleich von Placentarblut und Nabelschnurblut unter normalen und pathologischen Bedingungen zum Studium des Stoffwechsels der Placenta in situ einen Beitrag liefern kann.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Insulin and glucose levels were measured in eleven women in labour and in the umbilical arterial and venous blood of their babies. Twelve women received an infusion of 10 per cent glucose at a rate of 1 g. per minute for an average of 42·2 minutes. Thirteen women were given a similar infusion, and crystalline zinc insulin was added in a concentration of 1 unit to 3 g. of glucose. The average infusion time was 48·5 minutes.Exogenous insulin did not improve the transplacental passage of glucose.The infusion of glucose with insulin caused an eighteenfold increase in insulin level of the women in labour. This change was not reflected by the levels of insulin in umbilical blood. Similar umbilical insulin levels after both types of infusion show that exogenous insulin does not pass from the mother to the fetus during labour.An increase in the insulin level of umbilical blood began 22 minutes after the start of the infusion. This most probably reflects the poor capacity of the fetal pancreas to react to changes in blood glucose levels.
    Type of Medium: Electronic Resource
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