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  • 1
    Electronic Resource
    Electronic Resource
    Prevalence of congenital adrenal hyperplasia in Kuwait (1990)
    Springer
    European journal of pediatrics 149 (1990), S. 391-392 
    Details
    ISSN: 1432-1076
    Keywords: Congenital adrenal hyperplasia ; Salt loser ; 21-hydroxylase deficiency ; Ambiguous genitalia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Between 1978 and 1988 congenital adrenal hyperplasia (CAH) was diagnosed in 60 children in Kuwait with an estimated prevalence of 1∶9,000 livebirths, which is higher than that reported from Europe and Canada. In addition, there was presumptive evidence of CAH resulting in the death of 20 other children, giving a prevalence figure of 1∶7000. There were 41 girls (68%) and 19 boys (32%). Thirty-one of the girls (75.6%) and 11 of the boys (57.9%) were saltlosers. Fifty-four patients (90%) were diagnosed as 21-hydroxylase deficient, 3 patients (5%) had a deficiency of the 3β-hydroxysteroid dehydrogenase enzyme, and 3 patients (5%) showed a deficiency of 11β-hydroxylase.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02009655
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Prolonged and secondary fever in childhood bacterial meningitis (1989)
    Springer
    European journal of pediatrics 149 (1989), S. 114-116 
    Details
    ISSN: 1432-1076
    Keywords: Bacterial meningitis ; Fever ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In order to study the causes of prolonged and secondary fever in bacterial meningitis, a group of 102 infants and children with proven bacterial meningitis were studied. The causative agent wasHaemophilus influenzae in 58% of patients,Streptococcus pneumoniae in 25% andNeisseria meningitidis in 17%. Prolonged fever was observed in 12% of the patients. The established causes include, in order of frequency, subdural effusion, drug fever, otitis media, gastroenteritis and urinary tract infection. Secondary fever was noted in 18% of the patients. The causes, in order of frequency, were urinary tract infection, subdural effusion, otitis media, phlebitis, pneumonia and drug fever. Neither relapse of the meningitis nor inadequate response to antibiotic therapy was the cause for prolonged or secondary fever. Neurological sequalae were observed in 21 patients. There was no correlation between prolonged or secondary fever and neurological sequalae. We conclude that prolonged and secondary fever in patients with treated bacterial meningitis is rarely caused by the primary infection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01995859
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Cystic fibrosis and Helicobacter pylori gastritis, megaloblastic anaemia, subnormal mentality and minor anomalies in two siblings: a new syndrome? (1991)
    Springer
    European journal of pediatrics 150 (1991), S. 253-255 
    Details
    ISSN: 1432-1076
    Keywords: Cystic fibrosis ; Helicobacter pylori ; Megaloblastic anaemia ; New syndrome ; Autosomal recessive
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two siblings of consanguineous Arab parents were found to have cystic fibrosis and gastritis associated withHelicobacter pylori, folate deficiency megaloblastic anaemia, subnormal mentality and minor anomalies. The association ofH. pylori and megaloblastic anaemia has not been described in patients with cystic fibrosis.H. pylori infection and gastritis is probably more common in patients with cystic fibrosis than appreciated. We believe that the constellation of features in the two sibs represent a possible new autosomal recessive cystic fibrosis-like syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01955524
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    The value of red cell distribution width in the diagnosis of anaemia in children (1989)
    Springer
    European journal of pediatrics 148 (1989), S. 745-748 
    Details
    ISSN: 1432-1076
    Keywords: Red cell distribution width ; Mean corpuscular volume ; Anaemia ; Iron deficiency anaemia ; Haemoglobinopathies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The red cell distribution width index (RDW) was determined in 103 normal children, 69 iron-deficient (ID) patients, 73 with the thalassaemia trait, and 71 with other haemoglobinopathies. Elevated RDW values were found in anaemic patients, the highest values in ID anaemia, sickle thalassaemia, sickle cell anaemia, and β-thalassaemia trait in decreasing order. The normal RDW in children was 13.2±0.9 and an elevated RDW reflects active erythropoiesis. The RDW was elevated and the MCV low in all 69 patients with ID anaemia. The RDW was also elevated in 11/13 children with sickle cell anaemia, in 25/29 patients with sickle cellthalassaemia, and in all patients with thalassaemia major. The ID anaemia could be differentiated from the thalassaemia trait by the markedly elevated RDW in ID anaemia (mean= 20.7±3.2) and the mildly elevated RDW (mean 15.4±1.4) in thalassaemia trait. The RDW index discriminated better than Mentzer's index, discriminant function or the Shine Lal index. Thus the RDW is a good indicator of anisocytosis, and a good screening index especially for ID anaemia and the thalassaemia trait.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00443100
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    Paper (German National Licenses)
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