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  • 1
    Electronic Resource
    Electronic Resource
    Long-Term Trends in the Incidence of Distal Forearm Fractures (1998)
    Springer
    Osteoporosis international 8 (1998), S. 341-348 
    Details
    ISSN: 1433-2965
    Keywords: Key words:Distal forearm (wrist) fracture – Epidemiology – Incidence – Osteoporosis – Secular trends
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: In this population-based descriptive study covering the 50-year period, 1945–94, there was a statistically significant increase in distal forearm fractures due to severe trauma in both women and men (p 〈 0.001) but no secular increase in fractures due to moderate trauma (~ osteoporosis). Since fractures attributed to severe trauma comprised a greater proportion of the total in men (52%) than women (21%), an overall doubling of age-adjusted forearm fracture incidence in men between 1945 and 1994 was statistically significant (p 〈 0.001), but the 7% increase in age-adjusted rates among women was not (p= 0.90). While the epidemiological pattern of distal forearm fracture incidence in Rochester was similar to that seen elsewhere, the overall incidence rate of 287.4 per 100000 person-years (95% CI 267.7–307.1) in 1985–94 was less than current rates in Sweden, presumably because the great increase in distal forearm fracture incidence seen, for example, in Malmö between 1953–57 and 1980–81 was not observed in Rochester. The trends in distal forearm fracture rates in Rochester men and women over the past 50 years are broadly consistent with trends in hip fracture incidence in this community over the same time span.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001980050073
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  • 2
    Electronic Resource
    Electronic Resource
    Biochemical, histological, and biomechanical analyses of canine tendon (1987)
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 5 (1987), S. 60-68 
    Details
    ISSN: 0736-0266
    Keywords: Tendon ; Proteoglycan ; Anatomy ; Canine ; Fibrocartilage ; Histology ; Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: To define the matrix composition and architecture of canine flexor tendon, and to correlate tissue structure with applied mechanical loading, five anatomical regions of flexor tendon were studied. Histologically, two prominent fibrocartilaginous areas were observed on concave aspects of the tendon. The location of the major fibrocartilaginous area at the metacarpophalangeal joint correlated well with the region predicted by biomechanical modeling to be under greatest compressive loads during standing and claw movement. Comparative biochemical analysis showed an elevated water content, a fivefold higher hexuronic acid content, and a larger hydroxylysine/hydroxyproline ratio in this region relative to that for more tendinous areas. The major glycosaminoglycan component of fibrocartilaginous areas was chondroitin sulfate, whereas in other areas dermatan sulfate and hyaluronic acid dominated. Cell density and DNA analyses indicated a slightly higher cellularity for fibrocartilaginous areas and the region of vinculum insertion. These data document the existence of discrete areas of specialization within the flexor tendon that appear to be an adaptation to nutritional and mechanical factors.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jor.1100050109
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of postnatal age on the ultrastructure of six anatomical areas of canine flexor digitorum profundus tendon (1987)
    Hoboken, NJ [u.a.] : Wiley-Blackwell
    Journal of Orthopaedic Research 5 (1987), S. 231-241 
    Details
    ISSN: 0736-0266
    Keywords: Fibrocartilage ; Proteoglycans ; Collagen ; Postnatal age ; Ultrastructure ; Matrix ; Life and Medical Sciences
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: We report findings of a transmission electron microscopic study comparing the morphological appearance of cells and extracellular matrix of two fibrocartilaginous regions of canine flexor digitorum profoundus (FDP) tendon with that for typical tendinous regions. In addition, we determined the size distribution of collagen fibrils in six anatomical areas of the tendon from animals of three different ages. Average collagen fibril diameters for each of the six anatomical sites of 11-week-old FDP tendon were consistently different from that for older tissue. As growth proceeds, fibrils in tendinous regions almost double in size and take on a broad bimodal distribution. Collagen diameters in fibrocartilaginous areas do not increase, but rather decrease in size with age. Finally, the cells and associated pericellular matrix of fibrocartilaginous areas of adolescent and mature FDP tendon are ultrastructurally distinct from those of typical tendinous regions. On the contrary, the cellular morphology of 11-week-old tendon was invariant regardless of the anatomical region examined. In summary, fibrocartilage of canine FDP tendon, although not evident at 11 weeks of age, is well established by 6-12 months after birth and is the result of cellular and extracellular matrix specialization.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jor.1100050209
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    Paper (German National Licenses)
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