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  • 1
    Electronic Resource
    Electronic Resource
    Prediction of Creatinine Clearance from Serum Creatinine in Patients with Rheumatoid Arthritis: Comparison of Six Formulae and One Nomogram (2000)
    Springer
    Clinical rheumatology 19 (2000), S. 26-29 
    Details
    ISSN: 1434-9949
    Keywords: Key words:Calculation – Creatinine clearance – Estimation – Muscle mass – Pharmacology – Prediction – Renal function – Rheumatoid arthritis – Wasting formula
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The estimation of glomerular filtration rate is important for the medical treatment of patients with rheumatoid arthritis (RA). However, the determination of endogenous creatinine clearance (Clcr) from a 24-h urine collection is an unreliable and time-consuming procedure. We therefore tested the accuracy of six equations and one nomogram for the prediction of Clcr from serum creatinine (Scr) in 38 patients with RA and 20 controls. A positive correlation was found for all methods in the controls (r= 0.83–0.94) and RA patients (r= 0.51–0.69). The methods did not overestimate Clcr in RA. In the RA group the simple formula published by Cockcroft [Clcr = ((140 − age) × body weight)/(72 × Scr), × 0.85 for females] showed the best correlation with the measured Clcr. In RA the Cockroft formula can reliably be used to predict Clcr from Scr.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100670050006
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  • 2
    Electronic Resource
    Electronic Resource
    Avascular Areas on Nailfold Capillary Microscopy of Patients with Wegener’s Granulomatosis (2000)
    Springer
    Clinical rheumatology 19 (2000), S. 86-88 
    Details
    ISSN: 1434-9949
    Keywords: Key words:Avascular area – Giant loop – Nailfold capillary microscopy – Wegener’s granulomatosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: Over the past 25 years, nailfold capillary microscopy (NCM) has gained diagnostic value in the field of rheumatology based on descriptive data from patients with distinct connective tissue diseases (CTD). We prospectively analysed NCM findings from 116 patients selected for NCM by one of the following indications: (1) suspected diffuse or limited scleroderma or dermatomyositis, (2) evaluation of Raynaud’s phenomenon (RP) or (3) suspected small-vessel vasculitis. Nailfold haemorrhages, and enlarged and tortuous nailfold capillaries (‘lupus pattern’) were found to comparable degrees in patients with CTD and primary RP. Only giant loops, bushy capillaries and avascular areas indicated CTD; 92% of patients with Wegener’s granulomatosis (WG) had avascular areas. From all nailfold capillary abnormalities, only bushy capillaries, giant loops and avascular areas support a suspected CTD. A lupus-like pattern is not diagnostic. Avascular areas are a typical abnormality in patients with WG, for which NCM findings have not been described previously.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100670050022
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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