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  • 1
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Sociological inquiry 71 (2001), S. 0 
    ISSN: 1475-682X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Sociology
    Notes: Researchers estimate that 3-4 million women are abused by intimate partners each year, and the United States Surgeon General reports physical abuse as the leading cause of injury to women in the U.S. Although numerous studies have examined survivors’perceptions of domestic violence, few have examined battery from the perpetrator's perspective. We use a symbolic interactionist perspective to examine in-depth interviews with thirty-three male batterers and a demographically matched comparison group of twenty-five nonviolent male subjects. Our findings indicate that batterers minimize others’negative views of themselves, and they dissociate themselves from their partners’physical and emotional injuries. The comparison subjects, on the other hand, consider others’negative views of themselves, and they describe a deeper understanding of their intimate others’problems. We argue that an understanding of the batterer's perception of himself and others in domestic violence will help counselors develop techniques to stop male violence against women.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of communication 26 (1976), S. 0 
    ISSN: 1460-2466
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Media Resources and Communication Sciences, Journalism
    Type of Medium: Electronic Resource
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  • 4
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    Philadelphia, etc. : Periodicals Archive Online (PAO)
    Journal of Communication. 26:2 (1976:Spring) 98 
    ISSN: 0021-9916
    Topics: Media Resources and Communication Sciences, Journalism
    Notes: Research on Television and the Young
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  • 5
    ISSN: 1573-7225
    Keywords: Colon cancer ; diet ; family history ; United States ; women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: The purpose was to investigate whether dietary associations with risk of colon cancer in women differ by family history of the disease. Methods: Data were analyzed from a prospective cohort study of 35,216 Iowa (United States) women aged 55 to 69 years at baseline. Through 31 December 1995, 241 colon cancers were identified through record linkage with the State Health Registry. The cohort was stratified on family history of colon cancer in first-degree relatives; nutrient intakes were divided into tertiles. Results: Analyses using Cox regression revealed that the association of most dietary components with colon cancer incidence were similar for individuals with and without a family history. However, total calcium intake was associated inversely with colon cancer among women with a negative family history (relative risk [RR]=0.50 for upper cf lower tertile, P 〈 0.001), but was unrelated to incidence for women with a positive family history (RR=1.1 for upper cf lower tertile, P=0.69). Similarly, total vitamin E intake was associated with lower risk among women with a negative family history (RR=0.67 for upper cf lower tertile, P=0.04), but not among women with a positive family history (RR=0.87 for upper cf lower tertile, P=0.67). High intakes of fiber, fruits, and vegetables were each weakly inversely associated with risk among family-history negative women, but not among family-history positive women. Conclusions: These data, if corroborated, suggest that dietary factors typically associated with lower risk may be less effective risk-reduction interventions against colon cancer for individuals with a family history of colon cancer.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-7225
    Keywords: breast cancer ; breast density ; mammographic density ; risk factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: Mammographically defined percent breast density is an important risk factor for breast cancer, but the epidemiology of this trait is poorly understood. Although several studies have investigated the associations between reproductive factors and density, few data are available on the associations of breast density and waist-to-hip ratio (WHR), physical activity, education, alcohol and smoking. Methods: We investigated the associations of known and suspected breast cancer risk factors with breast density in a large breast cancer family study. Information was collected on members of 426 families through telephone interviews, mailed questionnaires and mammography. Mammographic films on 1900 women were digitized and breast density was estimated in discrete five-unit increments by one radiologist. Analysis of covariance techniques were used and all analyses were performed stratified by menopausal status. Results: Similar to other reports, nulliparity, late age at first birth, younger age and lower body mass index were associated with increased percent density in both premenopausal and postmenopausal women, and hormone replacement therapy among postmenopausal women. Higher levels of alcohol consumption and low WHR were associated with increased percent density among both premenopausal and postmenopausal women (differences of 3–11% between high and low categories). However, smoking and education were inversely associated with percent density among premenopausal (p = 0.004 and p = 0.003, respectively) but not postmenopausal women (p = 0.52 and p = 0.90). Physical activity was not associated with percent density in either stratum (p values 〉 0.25). Combined, these factors explained approximately 37% of the variability in the percent density measure in premenopausal women and 19% in postmenopausal women. Conclusions: Many of these factors may potentially affect breast cancer risk through their effect on percent breast density.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1573-7225
    Keywords: colon cancer ; disease stage ; hormone replacement therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objectives: Hormone replacement therapy (HRT) has been inversely associated with colon cancer incidence in several epidemiologic studies. In this study we used data from a population-based incident case–control study of colon cancer to evaluate the role of HRT use in survival after diagnosis with colon cancer. Methods: Data from 815 postmenopausal women living in Utah, California, and Minnesota diagnosed between 1 September 1991 and 30 September 1994 were used to examine associations between HRT and survival. Results: After adjusting for age at time of diagnosis, stage of disease at time of diagnosis, study center, and body mass index (BMI), we observed that women who had ever used HRT had a 30% lesser probability of dying of any cause and a 40% lower probability of dying from colon cancer specifically during the follow-up period. Further evaluation by years of HRT use showed that those who had used HRT for 4 or more years had the lowest risk of dying of colon cancer (hazard rate ratio 0.5, 95% confidence interval 0.3–0.9). Evaluation of other lifestyle variables with HRT use did not show significant confounding or effect modification. Conclusions: These findings suggest that HRT use may improve short-term survival after diagnosis with colon cancer; there is no suggestion that HRT use is detrimental to survival.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1573-2762
    Source: Springer Online Journal Archives 1860-2000
    Topics: Sociology
    Notes: Abstract Meta-analyses of 43 published studies comparingadult women's and men's interruptions duringconversations were conducted. Combined significancelevels and combined effect sizes were analyzed. Acrossstudies, men were significantly more likely than womento use interruptions. This difference, however, wasassociated with a negligible effect size (d = .15). Amore substantial effect size (d = .33) was found when studies looking specifically at intrusive typesof interruption were analyzed separately. Othermoderator variables were found to be related to gendereffects on the use of intrusive interruptions. Most notably, reports of gender differences inintrusive interruptions were more likely and larger inmagnitude when either women (versus men) were firstauthors, participants were observed in naturalistic(versus laboratory) settings, or participants wereobserved interacting in groups of three or more persons(versus in dyads). These results lend support to acontextual-interactive model of gender that emphasizes the importance of situational moderators ongender-related variations in social behavior.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    BioMetals 11 (1998), S. 331-343 
    ISSN: 1572-8773
    Keywords: Ca 2+ /calmodulin-dependent protein kinase IV ; calcium ; calmodulin ; CREB ; T lymphocyte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Ca 2+ /calmodulin dependent protein kinase IV (CaMKIV) is a multifunctional, serine-threonine protein kinase that is activated in the presence of increased intracellular calcium ( Ca 2+ ).CaMKIV is a potent medi-ator of Ca 2+ induced gene expression, primarily through its ability to phosphorylate and activate transcrip-tion factors such as CREB. CaMKIV-dependent activation of CREB is a key event in the expression of genes involved in the processes of T-cell activation and neuronal long term potentiation. The focus of this review is to describe the biochemical regulation of CaMKIV and examine how CaMKIV activates tran-scription in response to calcium in both cell and animal models.© Kluwer Academic Publishers
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-4919
    Keywords: sarcoplasmic reticulum ; Ca2+ release channel ; excitation-contraction coupling ; ryanodine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Summary Rapid mixing-vesicle ion flux and planar lipid bilayer-single channel measurements have shown that a high-conductance, ligand-gated Ca2+ release channel is present in ‘heavy’, junctional-derived membrane fractions of skeletal and cardiac muscle sarcoplasmic reticulum. Using the release channel-specific probe, ryanodine, a 30S protein complex composed of polypeptides of Mr ∼ 400 000 has been isolated from cardiac and skeletal muscle. Reconstitution of the complex into planar lipid bilayers has revealed a Ca2+ conductance with properties characteristic of the native Ca2+ release channel.
    Type of Medium: Electronic Resource
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