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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica 32 (1966), S. 2115-2122 
    ISSN: 0031-8914
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica 32 (1966), S. 494-496 
    ISSN: 0031-8914
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract Total knee replacement is a successful procedure with high clinical success rates. Problems are mostly initiated on the tibial side, and may be due to – amongst others – improper mechanical design of the tibial base plate. In this paper some new design concepts for the tibial component of a total knee prosthesis are presented. They are evaluated experimentally using a model for a proximal tibia, and strain gauge measurements and displacement measurements as experimental techniques. The designs are meant to yield a physiological load sharing between the trabecular and the cortical bone in the proximal tibia, and to minimize anterior lift-off of the tibial base plate. The optimal design required a metal backing of the plastic part and a thin continuous metallic rim in contact with the proximal tibial cortex. An optimal macro-composite structure within the plastic part was obtained by using thin steel wires in the transversal direction, connected to the metallic rim. With this optimal design, it was shown that the force required to close the anterior gap at simulated knee bending was smaller than 250 N, which can easily be applied clinically by an anteriorly placed clamp or bone screw.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 4 (1993), S. 407-414 
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: A wooden femur model was used together with matched cementless experimental implants to investigate the influence of some design concepts on the stress distributions within the proximal femur model, with emphasis on the longitudinal stresses on the outer bone surface, because the longitudinal stresses are believed to be the most important stresses in view of the laws of bone remodelling. In addition to the integration of alternative geometrical design concepts in a hip prosthesis design, the effect of using alternative materials upon bone stresses was also investigated. Stress evaluation was made by a combination of two-dimensional finite element analysis and strain-gauge measurements. The results and conclusions drawn from these experiments have led to a prototype of a so-called “physiological” hip prosthesis, in which are integrated a properly oriented collar, a hinge between stem and neck part, and a flexible stem.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-0827
    Keywords: Bone mechanics ; Bone composition ; Vitamin D3 ; Corticosteroid ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract The effects of 1α-vitamin D3 were studied for 6 months in 2-month-old male and female rats on a moderately low calcium diet with or without low-dose prednisolone treatment. Both cortical bone mechanical and biochemical properties were examined. Femoral bone specimens were subjected to torsional loading tests. With age, bone strength and stiffness increased in both sexes, accompanied by an increased degree of mineralization (bone ash and calcium concentrations). During growth, strength and stiffness increased more in male than in female rats. When 1α-vitamin D3 (0.5 μg/kg/day) was given alone, bone mechanical competence improved significantly whereas insulin-like growth factor-I (IGF-I) and calcium concentrations in the bone matrix were significantly reduced. Treatment with low-dose prednisolone (0.5 mg/kg/day) alone did not influence bone mechanical properties compared with intact control rats (without prednisolone) although a significant reduction in calcium concentration and an increased phosphorus concentration were measured. A combined therapy with prednisolone and 1α-vitamin D3 significantly increased bone strength, toughness, and stiffness compared with control bones. Both mineralization degree (ash and calcium concentration) and IGF-I concentration were decreased. We conclude that (1) mechanical properties of rat cortical bones improve relatively more in males compared with agematched females during growth which is related to increased bone mass and size, (2) low-dose prednisolone treatment does not change mechanical properties in males, and altered them only nonsignificantly in females despite a change in mineralization degree in both sexes; (3) treatment with 1α-vitamin D3 results in a consistent increase in mechanical competence of the bone accompanied by a significant decrease in IGF-I concentration in the bone matrix.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0827
    Keywords: Key words: Sodium fluoride — Trabecular and cortical bone — Bone mass — Bone geometry — Compressive and torsional tests.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Effects of fluoride on bone strength and cortical bone mass remain controversial. We compared 9-month, low-dose sodium fluoride (NaF) treatment with estrogen replacement therapy. Female Wistar rats 4.5 months old were divided into baseline, sham-operated (sham), sham-treated with NaF at 0.5 mg NaF/kg/day in drinking water, and ovariectomy (OVX), OVX treated with NaF and with estrogen. Bone mass was measured by dual X-ray absorptiometry (DXA) in vitro. Dimensions of the first lumbar vertebral body (L1) were determined by radiogrammetry. The right femur was processed undecalcified to obtain a midshaft cross-section to determine cross-sectional moments of inertia (CSMIs). L1 compressive test and left femoral torsional test were performed. OVX induced significant bone loss in L1 and femoral midshaft. Bone mass was increased to a greater extent in NaF-treated rats than in rats receiving estrogen replacement therapy. Femoral CSMIs in OVX rats, both L1 sizes and femoral CSMIs in NaF-treated rats, were significantly increased. Estrogen treatment had the least dimension expansion. OVX significantly decreased L1 compressive variables. There was no statistical difference in compressive parameters between NaF-treated groups and controls. OVX significantly increased femoral torsional strength but NaF treatment did not. Bone fluoride content was significantly increased after treatment with NaF. No significant difference in bone mineralization degree (ash and calcium) was found between treated and control rats. The discrepancy that an increase in bone mass and geometric properties in both trabecular and cortical bones by low-dose, long-term NaF treatment did not increase vertebral strength nor proportionally improve femoral strength indicated that the bone intrinsic biomechanical properties could be changed by NaF treatment.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A series of non pathological human tibial and femoral bones have been tested in torsional loading at high strain rates. Elastic (torsional stiffness) and ultimate properties (T max) have been determined. A geometrical description of the individual bone structures has been performed by determination of the polar moment of inertia (assuming axial symmetry), variation of this parameter along the long axis of the bone and length of the specimen between the grips. A fairly accurate prediction of mechanical behaviour of bone structures could be obtained using these geometrical parameters. The high variation of elastic and ultimate properties of whole bone structures in torsional loading is primarily the result of the high variation of polar moment of inertia for the different bone specimens.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Flow, turbulence and combustion 11 (1965), S. 286-292 
    ISSN: 1573-1987
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Summary Polycristalline copper surfaces and germanium single crystals were bombarded with 1000 eV argon ions. The argon ions were produced by means of an electron current between a heated tungsten cathode and an anode at a potential of +300 V. The pressure of the argon gas was maintained at 10−3 mm Hg. The whole system could be evacuated to 10−6 mm Hg with an oil diffusion pump. Before and after the bombardment, replica of the surface were made for investigation with the electron-microscope. After sputtering, dislocation steps appear at the surfaces, and the grain dimensions increase with increasing sputtering time. For the germanium single crystals, the dislocations seem to lie all in the same crystallographic direction.
    Type of Medium: Electronic Resource
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