ISSN:
0170-2041
Keywords:
Ketene dithioacetals
;
Saccharin derivatives
;
Carbon disulfide
;
Hydrazine hydrate
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Synthesis of [1,1,3-Trioxo-1,2-benzisothiazol-2(3H)-yl]ketene S,S-Acetals and Their Reaction with Hydrazine HydrateThe previously unknown ketene S,S-acetals 2, 3, and 4 are prepared by dithiocarboxylation reaction of methylene-active saccharin derivatives 1 in the presence of sodium hydride/carbon disulfide in dry DMF followed by alkylation. Compounds 2a, 3a, and 4a are treated with hydrazine hydrate (85%) to give 2-hydrazono-3,3-bis(methylthio)propiophenone (6a) and methyl or ethyl pyruvate 6b or 6c, respectively.
Additional Material:
1 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.1990199001170
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