ISSN:
1365-2133
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Sixteen skin tumours and one BCG vaccination granuloma were examined by 20-MHz B-scan ultrasound. Images were compared with closely matched histological sections of excised lesions. The correlation between histology and ultrasound was excellent for maximum tumour depth measurements (r=0.96, P〈0.0001), but less good for maximum width (r=0.84, P〈0.0001) because of the elastic contraction of tissue at excision. Architectural detail of lesions on histological sections corresponded well with that on ultrasound images. There was a good correlation for heterogeneity (collagen distribution vs. echo pattern (r=0.86, P〈0.0001)), and between collagen content and echogenicity of lesions (r=0.69, P〈0.003), Strong correlations were also obtained for echogenicity vs. spacing of collagen bundles (r=−0.65, P〈0.005), echogenicity vs. collagen bundle size (r=0.58, P〈0.02), and echogenicity vs. cellularity (r=−0.68, P〈0.003). Results for dermatofibroma were atypical, due to paradoxical low internal echogenicity and increased echo absorption. B-scanning is a reliable non-invasive method for assessing tumour dimensions, and has potential for the study of tumour characteristics for diagnostic purposes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1365-2133.1993.tb00229.x
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