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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 85 (1978), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Intact human Graafian follicles recovered during the preovulatory phase of the menstrual cycle and cultured in vitro, gave a mean oestradiol production of 33 ng/hour over periods of 4 to 92 hours. Treatment of follicles with human pituitary gonadotrophin or human chorionic gonadotrophin resulted in an increased production of oestradiol.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 260 (1976), S. 156-158 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Mature Large White gilts with 20- or 21-d oestrous cycles were assigned to one of four groups and given a single intramuscular injection of 500 or 1,000 IU of HCG (Organon) in saline on day 17, 18, 19 or 20 of the cycle. Ovulation occurs 40?42 h after such an injection given during prooestrus8,9. ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 31 (1975), S. 133-135 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Résumé Nous avons étudié les follicules de Graaf dans différents milieux de culture organique classique, le but éventuel étant de voir comment le LH provoque la reprise de la méiose. Les follicules ont été prélevés de l'ovaire de 16 truies se trouvant à différents stades du cycle oestrien et mis en culture sous pression augmentée (0.703 kg/cm2). En général, les couches de cellules et même l'ovocyte supportèrent bien la mode de culture décrit.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 214 (1967), S. 981-983 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Germ cells in developing female monkeys are considerably more resistant to radiation-induced cell death than those at equivalent stages of gametogenesis in rats and ...
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Chromosoma 22 (1967), S. 358-377 
    ISSN: 1432-0886
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Primordial oocytes (oocytes in primordial follicles) from human ovaries aged 51/2 months post conception to 11 3/4 years post partum were examined in: (a) squash preparations of fresh and fixed tissue; (b) histological preparations; and (c) thin sections by electron microscopy, in order to study the structure of the chromosomes. — The light microscope shows that the chromosome consists of a thread bearing numerous fine lateral appendages. Cytochemical tests indicate that the thread contains DNA, and is surrounded by material containing RNA and protein. — The electron microscope shows that there are three main structural components in the chromosome: (i) an axis or “core” containing at least two longitudinal strands about 200 Å thick; (ii) a surrounding sheath composed of coiled fibrils which form symmetrically arranged columns and loops, and (iii) clusters of large granules which are associated with the outer parts of the sheath. Small nucleoli and other granular bodies are also present. — These observations indicate the presence of lampbrush chromosomes in the human oocyte. The significance of this type of chromosome in mammals is discussed in relation to the differential radiosensitivity of the oocytes, and to the form of chromosomes at the dictyate stage in rodents.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 29 (1973), S. 1548-1550 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die Ultrastruktur der Rattenschilddrüse wird bis zu 8 Tagen in Organkulturen erhalten, was für radioautografische Studien der Ultrastruktur vorteilhaft ist.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-2072
    Keywords: R-DOM ; S-Amphetamine ; State-dependent discriminative responding ; Generalization of drug-induced stimuli
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of 0.75 mg/kg of R-DOM and 1.0 mg/kg of S-amphetamine served as discriminative stimuli in the control of a two-lever discrimination response. Dose-response evaluation of the two agents indicated that in S-amphetamine-trained animals the drug effects produced by test doses of 0.5 to 2.2 mg/kg of S-amphetamine could be considered as a dose-dependent continuum of low to high stimulus intensity. In R-DOM trained subjects, low to moderate doses of R-DOM (0.5–1.5 mg/kg) produced dose-related discriminative responding, but the high dose of R-DOM (2.2 mg/kg) resulted in random responding. When animals trained to discriminate 1.0 mg/kg of S-amphetamine from saline were given 0.5 or 0.75 mg/kg of R-DOM, they tended to respond on the drug correct lever. However, higher doses of R-DOM (1.5 and 2.2 mg/kg) produced random responding. Similarly, animals trained to discriminate 0.75 mg/kg of R-DOM from saline exhibited correct responses following 0.5 and 0.75 mg/kg of S-amphetamine, but not after 1.5 and 2.2 mg/kg. These data suggest that low doses of R-DOM produce discriminative stimuli that are qualitatively different from those of higher doses. Stimuli following low doses of R-DOM also appear similar in some respects to those following low doses of S-amphetamine.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-2072
    Keywords: DOM and amphetamine comparisons ; Operant behavior ; Motor activity ; Brain catecholamines ; Brain serotonin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A comparison of the behavioral pharmacology of DOM and amphetamine in rats indicated that lower doses (0.10–1.0 mg/kg) of the two agents had similar effects on schedule-controlled food-reinforced and shock-avoidance behavior. Similarities were also noted in their effects on horizontally directed motor activity when testing was preceded by a period of acclimation. However, most doses of DOM tended to decrease unacclimated motor activity, while amphetamine increased this behavior. Neuropharmacological antagonism studies indicated that brain catecholamines (CA) and serotonin (5-HT) are involved in the behavioral effects of both DOM and amphetamine. Cinanserin, a 5-HT receptor blocker, attenuated the behavioral disruptive effects of both agents on food-reinforced responding. Cinanserin attenuated the effects of all doses of DOM and those of higher doses of amphetamine on shock avoidance. When given prior to lower doses of amphetamine, there was a greater behavioral stimulation than when amphetamine was given alone. Prior depletion of brain CA with α-methyltyrosine (α-MT) did not affect DOM induced disruption of food-reinforced responding, while α-MT attenuated the behavioral effects of all doses of DOM and amphetamine on shock avoidance. These data suggest that DOM and amphetamine share a similar component in their mechanism of action which depends on the availability of a releasable pool of brain CA.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Radiation and environmental biophysics 6 (1969), S. 39-45 
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Summary A technique for maintaining mammalian ovaries in organ culture is described. Ovaries of rats, mice, monkeys and humans have been maintained in a histologically normal condition for up to 20 days in culture, during which many were X-irradiated. The doses of X-rays required to destroy all the primordial oocytes in organ cultures are similar to those reported forin vivo studies. The human foetal ovary is resistant to X-irradiation. Some oocytes survive for 7 days following exposure to 4000 R in organ culture. The radiation sensitivity of the human ovary is discussed: it would appear that it is amongst the most resistant to oocyte-killing known.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Plant and soil 86 (1985), S. 303-307 
    ISSN: 1573-5036
    Keywords: Aerosols ; Bulk precipitation ; Coastal ; Cycling ; Elements ; Filtering ; Leaching ; Literfall ; Nutrients ; Pinus radiata ; Throughfall
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Summary The accession and cycling of elements in a 14-year-old coastal stand ofPinus radiata D. Don was measured for one year. The element contents (mg m−2 year−1) of bulk precipitation and throughfall respectively were: NO3−N 41, 12; NH4−N 133, 154; organic-N 157, 396; Na 4420, 9700; K 387, 2900; Ca 351, 701; Mg 486, 1320. Of the increase in element content of rainwater beneath the forest canopy 20% (NH4−N), 70% (organic-N), 3% (Na), 90% (K), 20% (Ca) and 30% (Mg) was attributed to leaching; the remainder to washing of aerosols filtered from the atmosphere by the vegetation. The canopy absorbed approximately 40 mg m−2 year−1 of NO3−N. Litterfall was the major pathway for the above-ground biogeochemical cycle of N (93%), Ca (96%) and Mg (74%), and leaching was the major (73%) pathway for K.
    Type of Medium: Electronic Resource
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