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  • 1
    Electronic Resource
    Electronic Resource
    Askin's tumor in children: report of two cases (1992)
    Springer
    Pediatric surgery international 7 (1992), S. 73-75 
    Details
    ISSN: 1437-9813
    Keywords: Askin's tumor ; Peripheral neuroectodermal tumors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two cases of Askin's tumor of the thoracopulmonary region in children (a 6-year-old female and a 5-year-old male) are presented. Primary surgery was unfeasible and despite aggressive chemotherapy both died within 304 and 300 days, respectively, from the onset of the disease. Although rare, Askin's tumor should be considered in the differential diagnosis of any thoracopulmonary mass in childhood and adolescence through appropriate histology and immunohistochemistry of incisional biopsies. Its prognosis is poor unless radical surgery is performed as soon as possible: unresectable tumors can be treated with chemotherapy, but prolonged chemotherapy yields potentially lethal complications. We conclude that only early diagnosis and cytogenetic recognition can give children with Askin's tumor a chance of curative surgery.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00181010
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Early medical and surgical treatment of cryptorchidism: clinical, anatomic, and histologic findings (1992)
    Springer
    Pediatric surgery international 7 (1992), S. 368-371 
    Details
    ISSN: 1437-9813
    Keywords: Cryptorchidism ; Luteinizing hormone releasing hormone ; Human chorionic gonadotropin ; Orchidopexy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In 56 boys more than 6 month of age with cryptorchidism, luteinizing hormone releasing hormone (LHRH) was administered as a nasal spray 1.2 mg/day for 4 weeks. The nonresponders received human chorionic gonadotropin (HCG) 500 IU i.m. three times a week for 3 weeks. With the combined treatment, 46.5% of testes descended into the scrotum. Testicular descent occured more often in patients whose testes were located in a lower position. The initial position of the testes at clinical examination correlated significantly with the position at surgical inspection and the extent of epididymal malformation: the higher the clinical position of the testes, the more pronounced the maldescent and epididymal malformation. Histological findings indicated a paucity of germinal epithelium and atrophy of the Leydig cells. A significant inverse correlation existed between age at surgery and number of spermatogonia. Therefore, we advocate the earliest feasible treatment for cryptorchidism with a combination of LHRH and HCG, and for non-responders a surgical corrective procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00176596
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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