ISSN:
1437-2320
Keywords:
c-ALL
;
CNS relapse
;
polyradiculitis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A 15 year-old girl who had c-ALL diagnosed in 1982 was presented in our clinic suffering from an ascendend flaccid paresis and dysaesthesia of both legs. These are typical symptoms of polyradiculitis of the nerve roots L2-S2. A lumbal puncture revealed a pleocytosis with lymphoblasts which were up to 40% CD10 (cluster of differentiation) up to 70% CD19 and TdT (terminal transferase) positive. The diagnosis of late isolated CNS relapse was made. It is assumed that local residual infiltrations of leukemic cells into the nerve roots L2-S2 got into cell cycle and caused these rare CNS leukemia symptoms. Therefore the value of a craniospinal irradiation to prevent a CNS and systemic relapse is discussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00638898
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