ISSN:
0930-7516
Keywords:
Chemistry
;
Industrial Chemistry and Chemical Engineering
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Process Engineering, Biotechnology, Nutrition Technology
Notes:
A new process has been developed for indirect gas supply for culturing shear sensitive cells by means of a perfluorinated hydrocarbon. Hostinert 216, a perfluorinated polyether, was used as oxygen and carbon dioxide carrier. Hydrodynamics and mass transfer, required for industrial implementation, were investigated in a drop column. Based on the knowledge, obtained with indirect gas supply, it has been possible to construct a waste-gas free sterile pilot plant. Correlations derived from performed measurements permit design of and scale-up to an industrial plant.
Additional Material:
11 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/ceat.270140211
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