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  • 1
    Electronic Resource
    Electronic Resource
    Additive effect of nitric oxide and prostaglandin-E2 synthesis inhibitors in endotoxin-induced uveitis in the rabbit (1996)
    Springer
    Inflammation research 45 (1996), S. 203-208 
    Details
    ISSN: 1420-908X
    Keywords: Nitric oxide ; Prostaglandin E2 ; Diclofenac ; NG-nitro-L-arginine methyl ester ; Inflammation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The involvement of nitric oxide (NO) and prostaglandin E2 (PGE2) was investigated in a model of intraocular inflammation induced by intravitreal injection of endotoxin (lipopolysaccharide, LPS, 10 ng) in rabbits. The severity of uveitis, the myeloperoxidase (MPO) activity in iris-ciliary body, and the protein concentration in aqueous humor were determined. Nitric oxide synthase (NOS) and cyclooxygenase (COX) activities were assessed respectively by nitrite and PGE2 levels in aqueous humor. Treatment with inhibitors of NOS (NG-nitro-L-arginine methyl ester, L-NAME, 50 mg/kg i.p.) or COX (diclofenac, 30 μg, topically), alone or in combination, were compared to a salinetreated group. Diclofenac or L-NAME alone reduced or delayed the intensity of uveitis, and partially decreased the protein concentration in aqueous humor; diclofenac, but not L-NAME, partially reduced the polymorphonuclear leukocyte infiltration in the iris ciliary body as indicated by the MPO activity. Treatment with both inhibitors in combination diminished the clinical uveitis, the disruption of the blood-aqueous barrier and the MPO activity in the iris-ciliary body. We conclude that NO and PGE2 have additive effects in endotoxin-induced uveitis in rabbits, and that the inhibition of both pathways would improve the therapeutical management of uveitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02285162
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  • 2
    Electronic Resource
    Electronic Resource
    A retromedullary arteriovenous fistula associated with the Klippel-Trenaunay-Weber syndrome (1985)
    Springer
    Acta neuropathologica 66 (1985), S. 318-324 
    Details
    ISSN: 1432-0533
    Keywords: Intraspinal arteriovenous fistula ; Klippel-Trenaunay-Weber syndrome ; Hemangiomatosis ; Selective spinal arteriography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary An intraspinal vascular malformation associated with the Klippel-Trenaunay-Weber (KTW) syndrome initially was thought to be intramedullary on angiographic findings. Postmortem examination revealed an entirely posterior extramedullary arteriovenous fistula (AVF) fed by the anterior spinal artery. The association of the KTW syndrome with a so-called intramedullary AVF has been described in the literature without any pathologic confirmation (11 cases). Our case emphasizes the difficulty of determining the exact morphology and location of spinal AVF on arteriography. The association of the KTW syndrome with a retromedullary AVF can be explained on a developmental basis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00690965
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  • 3
    Electronic Resource
    Electronic Resource
    Role of vegetation cover in the biogeochemical balances of a small afforested catchment in southeastern Spain
    Amsterdam : Elsevier
    Journal of Hydrology 159 (1994), S. 275-289 
    Details
    ISSN: 0022-1694
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Architecture, Civil Engineering, Surveying , Geography , Geosciences
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0022-1694(94)90261-5
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  • 4
    Electronic Resource
    Electronic Resource
    Usefulness of MIB1 monoclonal antibody in assessing the proliferative index in human bladder carcinoma: comparison with Ki-67 antibody (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 25 (1994), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The reactivity of MIB1 antibody on routinely processed paraffin sections was compared with that of Ki-67 antibody on frozen sections of 80 transitional cell carcinomas of the bladder. The percentage of labelled cells was expressed as the labelling index. MIB1 labelling indices were higher than those of Ki-67 but for each case the two values were strongly correlated (r= 0.91). Ki-67 and MIB1 indices were also correlated to tumour grade and stage (P 〈inlineGraphic alt="leqslant R: less-than-or-eq, slant" extraInfo="nonStandardEntity" href="urn:x-wiley:03090167:HIS563:les" location="les.gif"/〉 0.001). MIB1 indices determined after both formaldehyde and ethanol based Bouin's fluid fixatives did not show any significant difference. MIB1 antibody staining after microwave oven heating of tissue sections is a simple technique for assessing the proliferative fraction of bladder tumours on fixed material. The use of MIB1 antibody permits retrospective studies and should determine whether the proliferation index in bladder carcinoma has the same prognostic value as demonstrated in other types of neoplasms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.1994.tb01375.x
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  • 5
    Electronic Resource
    Electronic Resource
    Suitability of Drought-Preconditioning Techniques in Mediterranean Climate (2003)
    Boston, MA, USA : Blackwell Science Inc
    Restoration ecology 11 (2003), S. 0 
    Details
    ISSN: 1526-100X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Arid and semiarid ecosystems in the Mediterranean are under high risk of desertification. Revegetation with native well-adapted evergreen shrubs is desirable, but techniques for successful establishment of these species are not fully developed. Transplant shock is a key hurdle to plantation success. The application of a drought-preconditioning treatment during the last months of nursery culture is a potential technique for reducing transplant shock. This technique has been widely applied in boreal habitats and humid temperate areas. Three representative Mediterranean species (Pistacia lentiscus, Quercus coccifera, and Juniperus oxycedrus seedlings) were exposed to classic drought-preconditioning treatment consisting of reductions in the watering regime. The effects of preconditioning on seedling quality were assessed by cell water relationships (pressure–volume curves), minimal transpiration, leaf capacitance, chlorophyll fluorescence, and gas exchange. Moreover, seedlings were exposed to transplant shock (intense drought period) during which water potential (predawn and midday) and maximal photochemical efficiency were evaluated to establish seedling performance. Results showed that preconditioning did not affect cell water relationships and minimal transpiration in any of the three species. Preconditioned seedlings of P. lentiscus maintained higher water content during desiccating conditions as a consequence of an increase in leaf water content at full turgor. These changes allowed plants to maintain higher net CO2 assimilation rates and an elevated photosystem II status, facilitating an increase in drought survival. Preconditioning improved the performance of Q. coccifera and J. oxycedrus seedlings, but these two species were much less responsive than P. lentiscus seedlings. Finally, results suggest that sensitivity to drought preconditioning may be related to drought tolerance or avoidance strategy of each species. Drought-related strategies should be considered to optimize management scale preconditioning.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1526-100X.2003.00172.x
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  • 6
    Electronic Resource
    Electronic Resource
    Coating-workpiece optimization of free cutting steels: turning with TiCN-, ZrO"2-, and ZrN-coated cemented carbide tools
    Amsterdam : Elsevier
    Surface & Coatings Technology 68-69 (1994), S. 762-769 
    Details
    ISSN: 0257-8972
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0257-8972(94)90250-X
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  • 7
    Electronic Resource
    Electronic Resource
    Interactions of landscape ecology, planning and design
    Amsterdam : Elsevier
    Landscape and Urban Planning 21 (1991), S. 3-11 
    Details
    ISSN: 0169-2046
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Architecture, Civil Engineering, Surveying , Geography , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0169-2046(91)90028-K
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  • 8
    Electronic Resource
    Electronic Resource
    Prognostic factors in superficial bladder cancer (1993)
    Springer
    World journal of urology 11 (1993), S. 148-152 
    Details
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A large body of evidence suggests that intravescial prophylaxis using vacilus Calmette-Guérin can favorably alter the natural history of superficial bladder cancer. The search for prognostic factors impacting the clinical alternative between conservative and radical treatment has been the subject of numerous efforts and remains a major objective in improving the carcinological results and the quality of life patients with superficial bladder cancer. In this regard, information is available on three levels: clinicopathological parameters, quantitative analysis, and biological markers. Recent advances in as well as the limitations and pitfalls of the use of three kinds of information in prognostication are reviewed. The proper use of prognostic factors will modify our attitude toward superficial bladder cancer in the near future.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00211409
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  • 9
    Electronic Resource
    Electronic Resource
    Assessing components of a competition index to predict growth in an even-aged Pinus nigra stand (1998)
    Springer
    New forests 15 (1998), S. 223-242 
    Details
    ISSN: 1573-5095
    Keywords: optimal radii ; influence zone overlap ; tree growth
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract The relationship between tree growth and competition may depend on some subjective choices that are commonly left to the researcher. Among these are the neighborhood radius, the number of years of growth that are integrated, and tree age. We have evaluated the importance of these factors when relating growth and competition in a forest stand with contrasted densities of the dominant tree species (Pinus nigra) and understory shrub species (Adenocarpus decorticans). Previous to this evaluation we performed a randomization test to assess the relationship between tree growth and neighbors. By using Daniels index of competition we found that the use of a fixed neighborhood radius underestimated the importance of tree competition. The coefficient of determination (r2) of the relationship between tree growth and Daniels index increased asymptotically with the number of years considered. Five years of growth gave high r2 independently of the density of trees and shrubs. The intensity of competition was weakly affected by the characteristics of the plot (tree and shrub densities), and did not change with time. In contrast, the potential growth at equal competition – as represented by constant “a” in the allometric model – changed with time suggesting a gradual decrease in potential tree growth in the plots with higher tree density, and a gradual increase in those plots with high density of shrubs. These results may reflect tree canopy closure and the senescence of Adenocarpus decorticans. A method is suggested to select optimum neighborhood radius and growing period for the calculation of competition indices. By applying this method we were able to explain as much as 79–84% of the variability in tree growth of this stand.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1006507017646
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  • 10
    Electronic Resource
    Electronic Resource
    Mapping Rain Composition in the East of Spain by Applying Kriging (1998)
    Springer
    Water, air & soil pollution 104 (1998), S. 9-27 
    Details
    ISSN: 1573-2932
    Keywords: kriging ; neutralization ; rain chemistry ; spatialdistribution ; western Mediterranean
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering
    Notes: Abstract This paper presents the results of applying kriging to the major inorganic ions from a bulk deposition network on the eastern coast of Spain that has been in operation for more than two years (October 1989 to December 1992). From the calculated variograms spatial correlation up to 70–130 km has been found, depending on the ion. The most suitable models of variograms have been found for sulphates and marine ions (chloride, sodium). Nitrates and pH correlates only at smaller distances. For calcium and pH additional to the correlation at smaller distances, a correlation at distances around 140 km was found. The nugget effect was high for most variograms, suggesting the importance of local influences in rain chemistry in the area. In general, most of the ions follow a spatial pattern that gives the highest values in the south and the lowest in the north inland part of the area of study. It is possible to discern different spatial patterns according to the ions and their main sources: A pattern following the coastline with decreasing values from the coast to inland was followed by chloride, sodium, magnesium and nitrate ions; a pattern divided into four areas, two with pH 〈 6.2 and less than 220 μeq L-1 for calcium and another two zones that surpass these values. Finally total sulphate and non-marine sulphate follow a pattern half-way between the previous patterns.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004993809263
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