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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 1 (1991), S. 0 
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: Physical perfomance was studied uniformly after intake of different antihypertensive drugs, and a comparison was made with placebo. The time needed to run 5000 m was studied in a nonhypertensive subject. In one of the different study periods, heart rate was continuously recorded during and after exercise. Physical perfomance was significantly reduced when a β-blocker was taken. The effect on physical capacity was strongly dose-dependent. With a high but conventional dose of a β-blocker, the time needed to run 5000 m was increased by more than 33%. No differences were observed between types of β-blockers. Physical capacity was slightly but significantly impaired when an α-blocker was taken; no differences in physical capacity between the drugs used and placebo were observed for a diuretic, a calcium antagonist or an inhibitor of the angiotensin-converting enzyme. The reduced physical perfomance seems to be caused by a reduction of the maximal heart rate as a result of the β-blockade. Thus, heart rate did not exceed 120 beats/min when the subject ran at maximal long-distance speed after intake of 100 mg of metoprolol, as recorded by continuous heart rate registration.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aim : To evaluate two simplified Helicobacter pylori eradication treatment alternatives for children and adolescents.Methods : Study subjects were identified by enzyme-linked immunosorbent assay and immunoblot in a family screening project. Helicobacter pylori infected 10–21 year olds were offered treatment, individuals with abdominal pain underwent upper endoscopy and those with peptic ulcers were excluded. Participants were randomized to either azithromycin 500 mg daily and tinidazole 500 mg two tablets daily in combination with lansoprasole 30 mg daily for 6 days (ATL-group) or with placebo (ATP-group). Urea Breath Test was performed at inclusion and after a minimum of 6 weeks after end of therapy.Results : In total, 131 individuals were randomized, of whom 31 (24%) had undergone upper endoscopy. Full compliance was achieved in 93% (122 of 131). The intention-to-treat eradication rate was 67% (44 of 66) and 58% (38 of 65) for the ATL- and the ATP-group, respectively.Conclusion : The double-blind randomized clinical trial did not identify a simplified, successful once daily H. pylori treatment for children and adolescents. Thus, twice daily proton pump inhibitor (PPI)-based triple therapies for 7 days remain as the choice of treatment in children. Further, powerful and controlled studies are needed to elucidate the best treatment strategies for H. pylori eradication in this age group.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Clinica Chimica Acta 79 (1977), S. 299-307 
    ISSN: 0009-8981
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0022-3999
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine , Psychology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Magnetism and Magnetic Materials 133 (1994), S. 561-563 
    ISSN: 0304-8853
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 69 (1991), S. 1146-1151 
    ISSN: 1432-1440
    Keywords: Health control ; Health promotion ; Prevention ; Laboratory examinations ; Evaluation ; Occupational medicine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two years after an extensive health examination at a Swedish industry, a follow-up study was carried out in 110 employees (94% of those initially examined). The control included a history of the subject's health, a physical examination, an electrocardiogram, urine and faeces examinations and 16 chemical analyses of whole blood or serum. Except for repeat examinations of those who had had initial values outside reference values, most of the chemical analyses meant nothing, leading to unnecessary expense and possible risk of either worried or complacent participants. The history and physical and laboratory examinations, aimed at finding factors which can be improved by changing the life style seem to be most beneficial. It is concluded that extensive health examinations, including a large number of laboratory examinations which are carried out at many industries as a health control, should be critically evaluated at these industries.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 26 (1984), S. 549-553 
    ISSN: 1432-1041
    Keywords: pafenolol ; hypertension ; antihypertensive therapy ; beta1-blocking agent ; exercise tests ; plasma levels
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Pafenolol, a new selective adrenergic beta1-blocking agent, has been tested for the first time in 6 hypertensive patients. After single oral doses of pafenolol 25 to 100 mg, there was a marked reduction in heart rate and systolic blood pressure during exercise tests. These effects were dose dependent. A significant positive correlation was found between the reduction in heart rate during exercise and the plasma level of pafenolol 5 hours after drug intake (correlation coefficient r=0.94). Side effects were mild and seemed to be dose dependent. It is concluded that this new beta1-blocking agent was effective in reducing blood pressure and was well tolerated.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1041
    Keywords: antihypertensive therapy ; sleep disturbances ; depression ; nightmares ; population study ; women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary Of 1302 women aged 44–66 years in a population study in Göteborg, Sweden, in 1974–75, who were representative of women of all the ages studied in the area, 165 were taking antihypertensive drugs, mostly β-blockers and diuretics. The prevalence of sleep disturbances, nightmares, tiredness and melancholia or depression was studied in the total population sample, and a comparison was made between women who were or were not taking antihypertensive drugs. In the entire population sample no significant difference was found between the various age strata studied, although with increasing age there was a trend towards fewer complaints of nightmares, but a larger number of sleep disturbances as a whole. No difference was found between women taking or not taking various types of single-drug therapy or combinations of antihypertensive drugs.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Holz als Roh- und Werkstoff 58 (2000), S. 344-352 
    ISSN: 1436-736X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: 3 , from Norway Spruce are presented. The measurements were carried out using a dynamic test method at equilibrium moisture content in 30% and 90% relative humidity. The test material, from two stands, was well defined with respect to growth conditions, material properties as knots and compression wood and position in the tree. Large variations in dynamic modulus of elasticity between the two moisture levels were found. For specimens from some trees, these variations were extremely large. The variations were not systematic within each tree as many other wood parameters. A part of the variations was explained by occurrence of compression wood and knots. A strong individual variation in stiffness between different trees was found. To achieve a more fundamental understanding of the relationships between stiffness and moisture content it appeared that also microscopic characteristics need to be taken into account.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1434-9949
    Keywords: Reliability ; Reproducibility ; Joint Mobility ; Function ; Rheumatic ; Rheumatoid Arthritis ; Population ; Epidemiology ; Women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Reliability and method error were assessed for 25 clinical tests by test-retest on 31 subjects with rheumatic disorder (RD) and on 28 consecutive non-RD of a reference group (REF) from a female population sample. Low systematic differences were found for joint mobility tests in the RD group and correlation coefficients were generally above 0.7. A significant difference in the RD group was found only for climbing stairs, and in the REF group for shoulder external rotation and flexion, wrist extension and grip strength. The relative method error of grip strength was large (17%). A new assessment of activities of daily living could not be fully evaluated because the population studies had limited disability, but the error was acceptable. Articular indices (Lansbury, Ritchie, and American Rheumatism Association) showed large method errors (9–25%), acceptable test-retest correlations (〉 0.75), and a systematic difference only in the Ritchie index. The analyses showed that a number of clinical tests are adequate for population studies of RD, but the metrical properties of these tests must be considered in the planning of clinical and population studies.
    Type of Medium: Electronic Resource
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