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  • 1
    Digitale Medien
    Digitale Medien
    Amsterdam : Elsevier
    International Journal of Psychophysiology 16 (1994), S. 185-189 
    ISSN: 0167-8760
    Schlagwort(e): Colour ; Electroretinogram ; Human ; Monkey ; Pattern stimulus ; Retina ; Vision
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Medizin , Psychologie
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 59 (1985), S. 423-425 
    ISSN: 1432-1106
    Schlagwort(e): ERG ; Monkey ; Gratings ; Ganglion cells
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Electroretinographic responses (ERG) to homogeneous light flashes and to alternating gratings were recorded from either eye of monkeys in which one optic nerve had been previously sectioned. Three weeks after optic nerve section the ERG response of the operated eye to alternating gratings was drastically reduced in amplitude and 5 weeks after surgery it was reduced to noise level. The uniform field ERG was unaffected. Histological examination of whole-mounted retinas of monkeys sacrified 6 and 8 weeks after optic nerve section showed a loss of ganglion cells in the operated eye. It is concluded that the integrity of ganglion cells is essential for the generation of a normal ERG response to gratings.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 59 (1985), S. 633-635 
    ISSN: 1432-1106
    Schlagwort(e): Retinal ganglion cells ; Cat ; Optic nerve cut ; Retrograde labeling ; HRP
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary After intracranial transection of the optic nerve in cats the retinal stump of the nerve was injected with HRP. Surviving retinal ganglion cells can be retrogradely labeled at least up to 15.5 months of postoperative survival.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    ISSN: 1432-1106
    Schlagwort(e): Area 18 ; Receptive field ; Velocity ; Spatial frequency ; Cat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The spatial frequency tuning curves of neurones of area 18 depend upon the velocity of the visual stimulus. The higher the velocity the lower the spatial frequencies to which the cell is tuned. Since in area 17 the size of the cell receptive field is inversely related with the optimal spatial frequency to which the cell responds, we have investigated whether the shift of the optimal spatial frequency with the velocity corresponds to a “change” in the receptive field size. We recorded extracellularly from neurones in area 18; for each cell we selected two gratings, one of high spatial frequency drifting at low velocity and another of low spatial frequency drifting at high velocity to which the cell gave comparable responses. The results show that the masking of the cells receptive field which abolishes the response to the high frequency low velocity grating does not prevent the cell from responding to the low frequency high velocity grating. We conclude that the size of the receptive field of neurones in area 18 depends upon the characteristics (spatial frequency and velocity) of the visual stimulus.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    ISSN: 1432-1106
    Schlagwort(e): Optic nerve section ; Cat ; Pattern ERG ; Retinal morphology
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Previous experiments have shown that the ERG response to alternating gratings vanishes gradually within 4 months after transection of the optic nerve, changes begin after 2–3 weeks. The response to gratings of low spatial frequencies deteriorates earlier than the response to gratings of high spatial frequencies (Maffei and Fiorentini 1981). Quantitative analysis of ganglion cell sizes in retinal wholemounts shows that ganglion cell shrinkage and ganglion cell loss begin at three weeks in the periphery of the retina, particularly in the temporal retina. The same morphological alteration subsequently becomes apparent also in the area centralis and the nasal retina, respectively. The main and early cell loss occurs among medium sized ganglion cells, supposedly the beta-cells. Among the alpha-cells only shrinkage is observed up to two months postoperatively. Light- and electron microscopic examination of cross sections through the retina show that pathological changes are restricted to the innermost layers.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 27 (1977), S. 335-345 
    ISSN: 1432-1106
    Schlagwort(e): Spatial frequency ; Visual neurones ; Mean luminance ; Cat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Experiments have been performed on unanaesthetized and paralysed cats. The tuning curves for spatial frequency of retinal, lateral geniculate and simple and complex cells of the cortex have been determined in response to sinusoidal gratings of various spatial frequencies at different levels of mean luminance. For all neurones, decreasing the mean luminance leads to a progressive loss of spatial resolution and contrast sensitivity. Retinal ganglion cells of type X show, for scotopic levels of luminance, a flattening of their spatial frequency tuning curves in the low spatial frequency range. For geniculate and cortical neurones, on the contrary, the spatial frequency characteristics at the various levels of luminance remain practically invariant in their bandwidth. On the average, complex cells still respond to mean luminances ten times lower than simple cells. The tuning curves for orientation of cortical cells maintain, to a first approximation, the same shape at the various levels of mean luminance. The results are discussed, comparing the electrophysiological with psychophysical data.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 14 (1971), S. 24-37 
    ISSN: 1432-1106
    Schlagwort(e): Cerebellum ; Inhibition ; Strychnine ; Picrotoxin ; Bicuculline
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Stimulation of the parallel fibres, or the mossy fibres, in the cerebellar cortex depresses the potential generated in the granular layer by anti-dromic invasion of the Purkinje cells (N1), and that generated by the axon discharge of granule cells (P2). The reduction of these potentials indicate inhibitions mediated respectively by basket and Golgi cells. The depressions of both N1 and P2 potentials are unaffected by strychnine at doses of up to 1 mg/kg. Picrotoxin and bicuculline reduce or suppress both inhibitions at doses of 2 to 5 mg/kg and 0.2 to 0.4 mg/kg respectively. The action of the picrotoxin is long lasting or even possibly irreversible, whereas that of bicuculline lasts only a few minutes. The ratio by weight between the dose of picrotoxin and that of bicuculline necessary to reduce the N1 and P2 depression exceeds 10. These results indicate that gamma-aminobutyric acid may be the chemical inhibitory transmitter at basket cell — Purkinje cell and Golgi cell — granule cell synapses.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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