ISSN:
1432-0800
Source:
Springer Online Journal Archives 1860-2000
Topics:
Energy, Environment Protection, Nuclear Power Engineering
,
Medicine
Notes:
Summary A method for the determination of low levels of PNP in rat and human urine was developed. The method involves acid hydrolysis of urine, extraction with benzene, derivatization of PNP with diazoethane, silica gel column chromatographic cleanup and gas chromatographic determination of the ethyl ether of PNP using an electron capture detector. Recoveries of fortified rat and human urine samples averaged in the range of 85–97%. The limits of detectability were 0.05 ppm for rat urine and 0.02 ppm for human urine. The method was applied to the analysis of PNP in urine of rats exposed to 0.1 and 0.01 LD50 of parathion.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01684992
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