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  • 1
    Electronic Resource
    Electronic Resource
    Endoscopic detection of submucosal guidewire placement during percutaneous dilatational tracheostomy (1996)
    Springer
    Intensive care medicine 22 (1996), S. 1276-1276 
    Details
    ISSN: 1432-1238
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01709353
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Prolonged cognitive dysfunction in survivors of critical illness (2005)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 60 (2005), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A prospective study using neuropsychological testing explored cognitive performance, and specifically executive function, in survivors of critical illness during the first year of recovery. Fifty-one patients who had survived 3 days or more in the intensive care unit were studied approximately 3 months after discharge; 45 of them were studied again 6 months later. General health was assessed using the Short-Form 36. Cognitive and executive functions were measured using Raven's Progressive Matrices, the Hayling Sentence completion test and the Six-Element Test. Three months after discharge from intensive care, all eight domains of Short-Form 36 were impaired among survivors; by 9 months, four of the eight domains showed significant improvement. At 3 months, 35% of patients scored at or below a level equivalent to the lowest performing 5% of a normal population (i.e. the fifth percentile) on two or more tests of cognitive function; by 9 months only 4% of patients were impaired to this extent. Although cognitive performance improved with time, it remained below normal.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.2005.04148.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A survey of physicians' attitudes to transfusion practice in critically ill patients in the UK (2002)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 57 (2002), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary This study aimed to examine the attitudes of intensivists and haematologists to the use of blood and blood products using a scenario-based postal questionnaire. One hundred and sixty-two intensivists and 77 haematologists responded to the survey. In four scenarios, the baseline haemoglobin thresholds for red cell transfusion ranged from 6 to 12 g.dl−1. There was significant variation between scenarios (p 〈 0.005). Increasing age, high Acute Physiology and Chronic Health Status II score, surgery, acute respiratory distress syndrome, septic shock and lactic acidosis significantly (p 〈 0.005) modified the transfusion threshold. There were greater variations in the baseline threshold for platelet transfusion. The majority of respondents (72.3%) selected a baseline haemoglobin threshold between 9 and 10 g.dl−1. The thresholds for platelet transfusion were far less consistent.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2002.02509_1.x
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  • 4
    Electronic Resource
    Electronic Resource
    Blood component use in critically ill patients (2002)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 57 (2002), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary This prospective observational study was conducted to assess the current transfusion practice in critically ill patients. One thousand two hundred and forty-seven consecutive critically ill patients admitted between February 1999 and October 1999 were included in the study. Overall 666 (53%) patients were administered red cells. Transfused patients had significantly higher intensive care unit␣mortality but also had higher Acute Physiology and Chronic Health Evaluation II scores and longer durations of stay. The average pretransfusion haemoglobin concentration was 〈 9 g.dl−1 in 75% of transfusion episodes. The common indications for transfusion were low haemoglobin (72%) and haemorrhage (25%). Overall, 202 (16%) and 281 (22%) of the patients were transfused platelets and fresh frozen plasma, respectively. The indications for transfusion were haemorrhage, low platelet counts, prolonged prothrombin time or to provide cover for invasive interventions. Most platelet transfusions were given at values in the order of 50–100 × 109.l−1. The pretransfusion platelet count varied according to the indications for transfusion. This study showed that transfusion practice is consistent and that in general there does not seem to be an excessive use of blood components in critically ill patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2002.02514.x
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  • 5
    Electronic Resource
    Electronic Resource
    A comparative study of periplast structure inCryptomonas cryophila andC. ovata (Cryptophyceae) (1986)
    Springer
    Protoplasma 131 (1986), S. 23-31 
    Details
    ISSN: 1615-6102
    Keywords: Cryptomonas ; Cryptophyceae ; Freeze-fracture/etch ; Periplast ; Scales
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Freeze-fracture followed by deep-etch was used with transmission electron microscopy to characterize and compare the periplasts of two cryptomonads,Cryptomonas ovata andC. cryophila. The periplast ofC. ovata consists of a dense surface mat of granular/fibrillar material overlying a series of polygonal plates attached to the undersurface of the plasma membrane (PM) at their upturned edges. Fracture faces of the PM reveal a highly stable substructure with distinct patterns of intra-membrane particles (IMPs) associated with the underlying plates; a role for the PM in plate development is indicated. The surface periplast component ofC. cryophila exhibits a cover of morphologically complex, overlapping heptagonal scales (termed rosette scales) in addition to elongate fibrils. The arrangement of IMPs within the PM is predominantly random and the inner periplast component consists of a sheet with regular pores where ejectisomes are located. The sheet does not appear closely associated with the PM. The combination of features exhibited by the periplast ofC. cryophila warrants its inclusion as a new type within theCryptophyceae.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01281684
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Pole reversal and the development of cell asymmetry during division in cryptomonad flagellates (1993)
    Springer
    Protoplasma 174 (1993), S. 19-24 
    Details
    ISSN: 1615-6102
    Keywords: Cell division ; Cell symmetry ; Cell polarity ; Komma ; Cryptomonas ; Periplast
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A unique form of cell division is reported for the cellsKomma caudata andCryptomonas ovata (Cryptophyceae). During cytokinesis, the posterior tail-like region of each daughter cell develops from the anterior region of the parental cell. This process, termed “pole reversal”, involves a major realignment in overall cell polarity as well as alterations to cytoplasmic and surface components. Pole reversal may be a consequence of flagellar apparatus transformation and reorientation during division, and pole reversal may facilitate the development of the asymmetric cell shape in daughter cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01404038
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  • 7
    Electronic Resource
    Electronic Resource
    Structure and development of the cryptomonad periplast: A review (1994)
    Springer
    Protoplasma 181 (1994), S. 106-122 
    Details
    ISSN: 1615-6102
    Keywords: Cryptophyceae ; Cell wall ; Periplast ; Self-assembly ; Freeze ; fracture-freeze etch
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The structure and development of the complex periplast, or cell covering, of cryptomonads is reviewed. The periplast consists of the plasma membrane (PM) plus an associated surface periplast component (SPC) and cytoplasmic or inner periplast component (IPC). The structure of the SPC and IPC, and their association with the PM, varies considerably between genera. This review, which concentrates on cryptomonads with an IPC of discrete plates, discusses relationships between periplast components and examines the development of this unique cell covering. Formation and growth of inner plates occurs throughout the cell cycle from specialized regions termed anamorphic zones. Crystalline surface plates, which comprise the SPC in many cryptomonad species, appear to form by self-assembly of disorganized subunits. InKomma caudata the subunits are composed of a high molecular weight glycoprotein that is produced within the endomembrane system and deposited onto the cell surface within anamorphic zones. The self-assembly of subunits into highly ordered surface plates appears closely associated with developmental changes in the underlying IPC and PM.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01666391
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  • 8
    Electronic Resource
    Electronic Resource
    Periplast development in cryptophyceae I. Changes in periplast arrangement throughout the cell cycle (1996)
    Springer
    Protoplasma 192 (1996), S. 28-39 
    Details
    ISSN: 1615-6102
    Keywords: Cryptophyceae ; Periplast ; Cell wall ; Cell division ; Anamorphic zones ; Pole reversal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The cell covering (or periplast) of many cryptomonads consists of discrete plate areas precisely arranged over most of the cell periphery. Developmental changes in periplast arrangement that occur throughout the cell cycle are examined here forKomma caudata andProteomonas sulcata [haplomorph]. In both cryptomonads, pole reversal occurs during cytokinesis, necessitating major realignment of the plate areas. Growth of the periplast occurs by addition of new plate areas to specialized regions (termed anamorphic zones) located around the vestibular margins and along the mid-ventral line of cells. Development of the periplast from these regions enables elongation and lateral expansion of cryptomonads throughout cell growth. Observed differences in cell division and periplast development between these genera are closely associated with variations in the arrangement of anamorphic zones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01273242
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Periplast development in Cryptophyceae II. Development of the inner periplast component inRhinomonas pauca, Proteomonas sulcata [haplomorph],Rhodomonas baltica, andCryptomonas ovata (1996)
    Springer
    Protoplasma 192 (1996), S. 40-48 
    Details
    ISSN: 1615-6102
    Keywords: Cryptophyceae ; Periplast ; Inner periplast component ; Freeze-fracture/etch ; Anamorphic zones
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The inner periplast component (IPC) of numerous cryptomonads is composed of discrete inner plates, situated beneath (and intimately associated with) the plasma membrane (PM). Freeze-fracture images reveal that the PM is organized into a series of ordered structural domains, which directly correspond in size and shape to the underlying inner plates. Freeze-fracture images are used here to compare IPC arrangement inRhinomonas pauca, Proteomonas sulcata [haplomorph],Rhodomonas baltica, andCryptomonas ovata, and to examine development of inner plates in these cryptomonads. In all genera examined, the IPC is highly ordered across most of the cell periphery but appears to be modified adjacent to the vestibulum and mid-ventral line, which represent the anamorphic zones. Variations in the size and shape of PM domains in these regions suggest that development of the IPC occurs within anamorphic zones, by the de novo formation and enlargement of inner plates throughout the cell cycle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01273243
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Periplast development in Cryptophyceae III. Development of crystalline surface plates inFalcomonas daucoides, Proteomonas sulcata [haplomorph], andKomma caudata (1996)
    Springer
    Protoplasma 192 (1996), S. 49-56 
    Details
    ISSN: 1615-6102
    Keywords: Cryptophyceae ; Periplast ; Surface periplast component ; Freeze-fracture/etch ; Cell wall ; Self-assembly
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary In several cryptomonad genera the surface periplast component (SPC) is composed of discrete crystalline plates surrounded by structurally distinct borders. Freeze-etch images enable detailed investigation of surface microarchitecture in these cryptomonads, and reveal that the plates consist of precisely aligned arrays of minute subunits. The plate borders are composed of similar subunits which display marked variations in alignment. Differences in the arrangement of subunits within the plates and borders appear closely linked to the organization of the underlying plasma membrane (PM) and inner periplast component (IPC). Development of the crystalline surface plates occurs within specialized anamorphic zones located along the mid-ventral line and around the vestibular margins of cells. Examination of variations in surface microarchitecture within anamorphic zones suggests that the crystalline plates form directly on the cell surface. Development of the surface plates results from the accumulation and self-assembly of subunits, while orderly addition of subunits to plate edges facilitates subsequent growth and enlargement. The close structural relationship between the SPC, PM, and IPC in these cryptomonads suggests that self-assembly of the surface plates may be mediated by developmental changes in the underlying PM and IPC.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01273244
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    Paper (German National Licenses)
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