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Lafora's disease and brain calcifications (1988)

Oster, S. ; Reske-Nielsen, E. ; Bruun, I.

Springer

Acta neuropathologica 76 (1988), S. 532-538

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ISSN: 1432-0533

Keywords: Lafora's disease ; Calcifications ; Astrocytes ; Combined stainings glial fibrillary acidic protein (GFAP)-PAS, GFAP-Bodian

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Summary The brain from a 22-year-old man with progressive myoclonal epilepsy (Lafora's disease) was examined. Besides widespread inclusion bodies in the nerve cells calcifications were seen on the inner and outer surface of the brain. No gliosis was present but the astrocytes were enlarged. They were unrelated to the inclusion bodies, as demonstrated in combined stainings with glial fibrillary acidic protein (GFAP)-PAS or GFAP-Bodian. A transport of an abnormal metabolic product is suggested.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00686395

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