ISSN:
0018-019X
Schlagwort(e):
Chemistry
;
Organic Chemistry
Quelle:
Wiley InterScience Backfile Collection 1832-2000
Thema:
Chemie und Pharmazie
Notizen:
The treatment of bromo-substituted 1,6-methano[10]annulenes with sodium thiolates in DMF provides easy access to alkylthio- and arylthio-substituted 1,6-methano[10]annulenes (Schemes 2-4). These compounds are then brominated with N-bromosuccinimide (NBS) to study their reactivity in electrophilic substitution reactions (Schemes 5 and 6). The resulting brominated thio-1,6-methano[10]annulenes are, in a subsequent reaction, subjected to Heck coupling with (4-nitrophenyl)acetylene (13) to produce the alkynylated derivatives 14 in reasonable yield (Scheme 7).
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1002/hlca.19970800113
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