Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Comparison of in vitro disc diffusion and time kill-kinetic assays for the evaluation of antimicrobial wound dressing efficacy (2005)
    Oxford, UK; Malden, USA : Blackwell Science Inc
    Wound repair and regeneration 13 (2005), S. 0 
    Details
    ISSN: 1524-475X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: There is a plethora of new silver-containing dressings on the market today. Various manufacturers attempt to show that their dressings are the most efficacious and therefore should be preferentially employed by health care workers based on the results of their in vitro tests. However, there have been no studies that clearly identify which tests are appropriate for comparison purposes. The purpose of this study was to determine which in vitro test is most appropriate for evaluating the antimicrobial efficacy of silver-containing dressings. This was done by testing seven silver-containing dressings and two non-silver-containing topical agents against 17 clinically relevant microorganisms using zone of inhibition assays and time-kill kinetic assays in complex media. The results for the two assays were then correlated to determine whether the methods generated similar results. It was determined that the two methods do not correlate at all. This is most likely a result of the silver interacting with the media in the zone of inhibition test, thus invalidating the results of this test. We therefore conclude that zone of inhibition data generated for silver-containing dressings is of little value when assessing antimicrobial efficacy and that time-kill assays are of greater use.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1067-1927.2005.130409.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    114
A Comparison of in vitro Disc Diffusion and Time-Kill Kinetic Assays for the Evaluation of Antimicrobial Activity of Silver Containing Wound Dressings (2004)
    Oxford, UK; Malden, USA : Blackwell Science Ltd/Inc.
    Wound repair and regeneration 12 (2004), S. 0 
    Details
    ISSN: 1524-475X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: There is a plethora of new silver containing dressings on the market today. Various manufacturers attempt to show that their dressings are the most efficacious and therefore should be preferentially employed by health care workers based on the results of their in vitro tests. However, there have been no studies to date that clearly identify which in vitro tests are appropriate for comparison purposes. The available literature suggests that there are problems with disc sensitivity assays in terms of assessing the antimicrobial efficacy of silver. Spadaro (1985) has shown that the diameters of zones of inhibition were not proportional to the concentration of anodic silver in complex test media. Further, Richards et al (2001) have shown that zones of inhibition did not appear to correlate to log reduction assay data for silver containing dressings. Other authors favour log reduction or time kill assays as they better compare to clinical data. The purpose of this study was to determine which in vivo test is most appropriate for evaluating the antimicrobial efficacy of silver-containing dressings. This was done by testing 8 different silver containing dressings and 2 non-silver (mafenide acetate or hexamethylene biguanide) containing topical agents against 17 clinically relevant microorganisms using both zone of inhibition assays and time-kill kinetic assays in complex media. The results for the two assays were then correlated to determine if the methods generated similar results. It was determined that the two methods do not correlate at all. This is most likely a result of the silver interacting with the media in the zone of inhibition test, thus invalidating the results of this test. We therefore conclude that zone of inhibition data generated for silver-containing dressings is of little value when assessing antimicrobial efficacy, and that time-kill assays are of greater use.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1067-1927.2004.0abstractdh.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Early healing events in a porcine model of contaminated wounds: effects of nanocrystalline silver on matrix metalloproteinases, cell apoptosis, and healing (2002)
    Malden, USA : Blackwell Science Inc
    Wound repair and regeneration 10 (2002), S. 0 
    Details
    ISSN: 1524-475X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A porcine model of wound healing was employed to examine the impact of nanocrystalline silver–coated dressings on specific wound healing events. Full-thickness wounds were created on the backs of pigs, contaminated with an experimental inoculum containing Pseudomonas aeruginosa, Fusobacterium sp., and coagulase-negative staphylococci, and covered with dressing products either containing silver or not. Nanocrystalline silver-coated dressings promoted rapid wound healing, particularly during the first several days post-injury. Healing was characterized by rapid development of well vascularized granulation tissue that supported tissue grafting 4 days post-injury, unlike control dressed wounds. The proteolytic environment of wounds treated with nanocrystalline silver was characterized by reduced levels of matrix metalloproteinases. Matrix metalloproteinases have been shown to be present in chronic ulcers at abnormally high levels, as compared with acute wounds, and may contribute to the nonhealing nature of these wounds. Cellular apoptosis occurred at a higher frequency in the nanocrystalline silver–treated wounds than in wounds dressed with other products. The results suggest that nanocrystalline silver may play a role in altering or compressing the inflammatory events in wounds and facilitating the early phases of wound healing. These benefits are associated with reduced local matrix metalloproteinase levels and enhanced cellular apoptosis. (WOUND REP REG 2002;10:)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1524-475X.2002.10308.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Fungitoxicity of organoantimony and organobismuth compounds (1983)
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 31 (1983), S. 85-88 
    Details
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jf00115a023
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Development of an optimal heterotrophic growth medium for Chlorella vulgaris (1984)
    Springer
    Applied microbiology and biotechnology 20 (1984), S. 281-283 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Final biomass yields of Chlorella vulgaris cultured heterotrophically in bristol medium amended with 0.1% (w/v) yeast extract (Difco) or 0.5% glucose (w/v) were 26 and 58 times higher, respectively, than yields obtained for autotrophically grown cells in the light. Similarly, final biomass increases were 35 and 138 fold for these organic substrates in the dark. The mixture of 0.1% yeast extract and 0.5% glucose was optimal and produced increases in final biomass of 70 and 140 times in the light and dark, respectively.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00250641
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Interactions between the solvent acetone and the pyrethroid insecticide permethrin on activities of the blue-green algaAnabaena (1980)
    Springer
    Bulletin of environmental contamination and toxicology 24 (1980), S. 562-569 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01608156
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Interactions of the solvent acetone with the fungicides benomyl and captan in fungal assays (1980)
    Springer
    Bulletin of environmental contamination and toxicology 25 (1980), S. 554-561 
    Details
    ISSN: 1432-0800
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01985571
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Detection and analysis of interactions between atrazine and sodium pentachlorophenate with single and multiple algal-bacterial populations (1985)
    Springer
    Archives of environmental contamination and toxicology 14 (1985), S. 167-177 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract A multispecies-multitoxicant defined microcosm was studied by examination of its various components. Determination of population interactions showed thatChlorella vulgaris inhibitedAnkistrodesmus braunii by 32%. The presence ofChromobacterium violaceum resulted in a further inhibition ofA. braunii (17%) but its presence had no effect onC. vulgaris. Sensitivity of the two algae and the bacterium were determined for the toxicants atrazine1 and sodium pentachlorophenate, both singly and in combination. While both algae were sensitive to the toxicants, the combined effect of the toxicants on the individual populations was additive. In mixed cultures with one toxicant present, a synergistic interaction was detected between sodium pentachlorophenate andC. vulgaris with respect to A.braunii. Further, the combination ofA. braunii and atrazine withC. vulgaris resulted in an increased inhibition ofC. vulgaris. These observations indicate that biological-chemical interactions can occur as do population-population and chemical-chemical interactions. When mixed cultures of the algae were treated with both toxicants, chemical antagonism was observed. This antagonism was modified by the presence of the bacterium but it was not eliminated. It was concluded that the techniques allowed determination of the interactions in a complex microcosm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01055608
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Technique for identifying and minimizing solvent-pesticide interactions in bioassays (1982)
    Springer
    Archives of environmental contamination and toxicology 11 (1982), S. 437-445 
    Details
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract A simple, reliable, and accurate technique is presented for identifying and analyzing solvent-pesticide interactions in bioassays. This method used the solvent acetone, the fungicides metalaxyl and captan, and the fungiPythium ultimum, Sclerotinia homeocarpa, andPestalotia sp. Conclusions obtained were tested and verified by procedures specifically developed for both water-soluble and -insoluble pesticides. The interaction response observed with any given set of bioassay parameters was dependent upon both the acetone and fungicide concentrations. However, the method compensates for these discrepancies in interaction response and indicates the most suitable test parameters to employ in subsequent bioassays.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01056070
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Biomass production from the green algae Chlorella vulgaris and Ankistrodesmus braunii cultured heterotrophically (1984)
    Springer
    Biotechnology letters 6 (1984), S. 507-510 
    Details
    ISSN: 1573-6776
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Ankistrodesmus braunii and Chlorella vulgaris were cultured heterotrophically under various operating conditions. The maximum rate of biomass production was 900 and 900 mg L-1 d-1 by C. vulgaris and 1000 and 700 mg L-1 d-1 by A. braunii in the light and dark, respectively. This indicates that these algae could produce in excess of 1530 dry weight tonnes ha-1 y-1 which is 10–20 times higher than the maximum production levels in the literature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00139993
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...