ISSN:
1573-2568
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A study of the alteration of secretory patterns through the use of Heidenhain pouches in twoMacaca nemestrina, following subcutaneous injection of a gastrin preparation, revealed that the response was more reliable when the dorsal trunk, rather than the anterior thigh, was utilized as the site of injection. A plateau of maximal secretory response was obtained when 18–25 mg. of the extract per kilogram of body weight was injected. Although the observations were not conclusive, they suggested that pepsin is liberated by a “washing-out” process but is also continuously secreted in response to continued stimulation with gastrin extract. Evaluation of the monkey's response to stimulation by gastrin extracts established that theMacaca nemestrina is a different type of experimental animal when compared to the dog. The dog shows a response of gastric secretion to much smaller amounts of the gastrin extract and is less sensitive to other stimuli of an external nature.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02232923
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