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  • 1
    Electronic Resource
    Electronic Resource
    The central nervous system in systemic lupus erythematosus (1991)
    Springer
    Rheumatology international 11 (1991), S. 117-119 
    Details
    ISSN: 1437-160X
    Keywords: Lupus ; Neuropsychiatric illness
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Management of central nervous system (CNS) involvement is one of the most challenging problems in systemic lupus erythematosus. This article reviews the spectrum of CNS manifestations present in this disease, their diagnosis and pathogenesis, as well as an approach to their treatment and prognostic implications.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304499
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Hypertrophic cardiomyopathy and systemic lupus erythematosus (1998)
    Springer
    Clinical rheumatology 17 (1998), S. 531-533 
    Details
    ISSN: 1434-9949
    Keywords: Heart disease ; Hypertrophic cardiomyopathy ; Systemic lupus erythematosus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report the case of a 45 year-old woman with systemic lupus erythematosus (SLE), who developed clinical and echocardiographic signs of hypertrophic cardiomyopathy. Neither a family history of cardiomyopathy or sudden death nor a personal history of of hypertension or valvular lesions were present. The association of SLE with hypertrophic cardiomyopathy has been previously described in only 2 patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01451294
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Sjögren’s Syndrome and Hepatitis C Virus (1999)
    Springer
    Clinical rheumatology 18 (1999), S. 93-100 
    Details
    ISSN: 1434-9949
    Keywords: Key words:Cryoglobulinaemia – Hepatitis C virus – Sjögren’s syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: Sjögren’s Syndrome (SS) is an autoimmune disease that mainly affects exocrine glands and usually presents as a persistent dryness of the mouth and eyes. The spectrum of the disease extends from an organ-specific autoimmune disease to a systemic process. Viral infection has long been suspected as a potential cause of SS because several viruses have been incriminated in the aetiology of this disease, and a possible relationship between SS and hepatitits C virus (HCV) was postulated in 1992. In this paper, we review the literature concerning SS and HCV infection and summarise the current knowledge regarding their association and their pathogenic, clinical and immunological significances. The main conclusions of this review are that the prevalence of antibodies to HCV in patients with primary SS ranges between 14 and 19% using third-generation ELISA, chronic HCV infection may mimic the main clinical, histological and immunologic features of ‘primary’ SS and, finally, testing for HCV infection must be performed in patients with SS, especially in those patients with evidence of liver involvement or associated cryoglobulinaemia. HCV seems to be a rare cause of ‘primary’ SS in the absence of recognised liver disease or cryoglobulinaemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100670050064
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Anticardiolipin antibodies in patients with autoimmune diseases: Isotype distribution and clinical associations (1989)
    Springer
    Clinical rheumatology 8 (1989), S. 475-483 
    Details
    ISSN: 1434-9949
    Keywords: Anticardiolipin Antibodies ; Antiphospholipid Antibodies ; Autoimmune Diseases ; Systemic Lupus Erythematosus ; Thrombosis ; Thrombocytopenia ; Haemolytic Anaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A prospective study of IgG and IgM isotypes of anticardiolipin antibodies (aCL) was performed in a series of 167 patients with various autoimmune diseases, including rheumatic and nonrheumatic disorders, and in a group of 100 healthy blood donors. The IgG aCL serum was regarded as positive if a binding index (BI) greater than 2.85 (3.77 SD) was detected and a BI greater than 4.07 (3.90 SD) was defined as positive for IgM aCL. Forty patients (24%) were found to be positive for IgG and/or IgM aCL. IgG aCL were detected in 23% of patients with systemic lupus erythematosus (SLE), in 9% with idiopathic thrombocytopenic purpura, in 7% with progressive systemic sclerosis, and in 6% with dermatomyositis-polymyositis. IgM aCL were present in 43% patients with primary biliary cirrhosis, in 33% with rheumatoid arthritis, in 22% with SLE, and in 8% with giant-cell arteritis. IgG aCL were found to have a significant association with thrombosis and thrombocytopenia, and IgM and aCL with haemolytic anaemia and neutropenia, in SLE but not in the other autoimmune diseases. The identification of these differences in the aCL isotype associations, depending on the autoimmune disorder, may improve the clinical usefulness of these tests.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02032099
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Optic neuropathy in the “primary” antiphospholipid syndrome: Report of a case and review of the literature (1997)
    Springer
    Clinical rheumatology 16 (1997), S. 629-631 
    Details
    ISSN: 1434-9949
    Keywords: Optic Neuropathy ; Antiphosphilipid Syndrome ; Antiphospholipid Antibodies ; Anticardiolipin Antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Several visual disturbances have been associated with the presence of antiphospholipid antibodies, including vaso-occlusive retinopathy and ischaemic optic neuropathy. The latter has been rarely described in patients with “primary” antiphospholipid syndrome, and, when present, is generally associated with neurological disorders. We describe the case of a patient presenting with optic neuropathy in whom a “primary” antiphospholipid syndrome was diagnosed, and review all previously reported similar cases. The pathogenesis and treatment are also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02247807
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    Paper (German National Licenses)
    Fulltext
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