ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] RECENTLY, in discussing dihydrofolate reductase, Gready1 described, with the emphasis on our paper2, the finding that the inhibitor, methotrexate, binds to the enzyme with its pteridine ring 'upside down' with respect to the substrates dihydrofolate and folate. It is essential to point out that the ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/286309a0
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