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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Mathematische Zeitschrift 134 (1973), S. 329-336 
    ISSN: 1432-1823
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1106
    Keywords: Slow potential change ; Spreading depression ; Cortex ; Naloxone ; Electroconvulsant shock ; Microiontophoresis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The slow potential change (spc) accompanying spreading depression (SD) was studied in rats and in a seizure-sensitive strain of Mongolian gerbil under three different experimental paradigms, each involving the use of naloxone. Gerbils undergoing electroconvulsive shock treatment displayed SD during the post-ictal phase, which was blocked by the intraperitoneal (i.p.) administration of naloxone (20–50 mg kg-1). Topical application of naloxone to the exposed cortex of the anaesthetized gerbil and rat blocked the spc of SD evoked by KCl. Microiontophoretic ejection of naloxone during extracellular recordings reversed cell refractoriness following the spc, demonstrated by the observation of a maintained sensitivity to iontophoretic pulses of glutamate. The results suggest a possible involvement of naloxone-sensitive processes in the mechanism responsible for cortical SD.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1106
    Keywords: Rat ; Luminance detector ; Darkness detector ; Pupil ; Sympathectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In order to identify the pretectal nucleus which contains pupillomotor cells in the rat, cells were sought which were sensitive to changes in luminance level at the eye. Two types were found: Luminance detectors which showed a graded increase in firing with increase in luminance, and darkness detectors which showed a graded increase in firing rate with graded dimming of luminance intensity. All luminance detectors were located in the olivary pretectal nucleus, whereas darkness detectors were located in the posterior pretectal nucleus. Consensual pupil responses were recorded in conscious normal and sympathectomised rats using an infra-red sensitive T.V. pupillometer. Pupil diameter varied 2mm in an approximately linear fashion over six log units range in luminance intensity. Sympathectomy produced a general constriction of the pupil, but the overall response to light was unaffected. The changes in pupil size occurred over the same range of luminance that the firing rates of both luminance and darkness detectors changed. The olivary pretectal nucleus may therefore be involved in pupilloconstruction in the light, and the posterior pretectal nucleus, with pupillodilation in the dark.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1106
    Keywords: Pretectal luminance detectors ; Pupillary responses ; Iris sphincter muscle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The luminance detectors in the olivary pretectal nucleus, which are likely candidates mediating the pupillary light reflex, responded to all frequencies of sinusoidally modulated light up to 12–25 Hz. At low frequencies (0.05–4.0 Hz) the luminance detectors responded with modulated firing to different stimulation rates. The modulation depth of the cell response increased with the increase in stimulation frequency up to 20 Hz, then rapidly fell. There was a delay between the peak intensity of the stimulus and the peak firing of cell response of about 30–40 ms. The amplitudes of the consensual pupil responses to the same sinusoidal stimulus, on the other hand, decreased with an increase in frequency and no discernible response was recorded above 2 Hz. The pupil responses were little affected by sympathectomy. The differences in the frequency response characteristics of luminance detectors and the pupil were attributed to the sluggish dynamic properties of the pupil muscles. This was demonstrated using an electronic model of the iris muscle which modified the responses of the luminance detectors giving output waveforms broadly resembling pupil responses to square and sinusoidally modulated lights.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 3721-3726 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Guided compression offers an attractive route to explore some of the physics issues of hot electron heating and transport in the fast ignition route to inertial confinement fusion, whilst avoiding the difficulties associated with establishing the stability of the channel formation pulse. X-ray images are presented that show that the guided foil remains hydrodynamically stable during the acceleration phase, which is confirmed by two-dimensional simulations. An integrated conical compression/fast electron heating experiment is presented that confirms that this approach deserves detailed study. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 225 (1970), S. 1219-1222 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN July 1969, while two of us (R. J. C. and F. C. H.) were examining the australopithecine collections in the Transvaal Museum (Pretoria), one of us (R. J. C.) noticed that parts of a cranium (SK 847) from Swartkrans appeared to differ substantially from the robust australopitheeine (Paranthropus) ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of anthropology 15 (2000), S. 185-189 
    ISSN: 1824-3096
    Keywords: H. erectus ; H. ergaster ; artefacts ; migrations
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract If the genusHomo did indeed originate in Africa, then it must have spread by about 2 m.y. ago into Asia where it is represented at 1.8 m.y. ago byHomo erectus fossils. This latter species in turn eventually spread back into Africa, as indicated by the 1.4 m.y. old OH 9 calvaria from Olduvai, and into Europe, as indicated by the 800,000 year old Ceprano calvaria from Italy. These hominids are associated only with Oldowan style artefacts of cores, choppers and flakes and were apparently not conversant with Acheulean handaxe technology. It seems that they most probably evolved viaHomo heidelbergensis into the Neanderthals. Meanwhile, a completely separate development originating withHomo ergaster of about 1.7 m.y. ago in Africa and possessing Acheulean handaxe technology evolved via such forms as Ndutu and Steinheim intoHomo sapiens.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Studies of the in vivo metabolism of 10,11-dihydrodibenz[b,f]-1,4-oxazepin-11-(1OH)-one (2) specifically deuteriated at C-7 implicate an arene oxide intermediate during the conversion to 7-hydroxy-2 (4) as evidenced by the observation of the NIH shift.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 232 (1971), S. 308-312 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Restoration of a hominid skull recovered from Bed I at Olduvai Gorge has revealed it to be a member of the genus Homo. Although the new cranium resembles H. habilis from Bed II, it differs in some respects from the type of H. habilis from Bed I. This may be a case of sexual ...
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Human evolution 12 (1997), S. 221-232 
    ISSN: 1824-310X
    Keywords: Oreopithecus bambolii ; fossil primate ; Miocene ; skull reconstruction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The crushed skull ofOreopithecus bambolii (IGF 11778) has been fully reconstructed in Florence, Italy and shows important differences with previous drawn reconstructions. The jaws are massive and projecting, such that the face is not as short as was believed. The incisors are small and do not project significantly forward beyond the position of the canines, and the anterior symphyseal surface of the mandible projects in front of the canines and well infront of the upper canines and incisors. There is a prominent sagittal crest, a high ascending mandibular ramus, and a nuchal plane which faces postero-inferiorly.
    Type of Medium: Electronic Resource
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