Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1432-0738
    Keywords: Methyl mercury ; Toxicokinetics ; Differential toxicity ; Japanese quail ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Distribution of a single oral dose of methyl mercury (10 mg Hg/kg body weight) was followed from 90 min up to 120 h in plasma, erythrocytes, and brain of Japanese quails and rats. Significantly higher Hg concentrations were observed in plasma and brain of quails and red blood cells of rats. Blood/brain ratio decreased in quails from 6 to 2 at 24 h and 120 h respectively, whereas it increased in rats. Erythrocyte/plasma ratio in quails was about three times lower and averaged 54. The differences in Hg distribution were accompanied by a more than 3-fold higher acute toxicity in quails under adequate experimental conditions.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica 28 (1962), S. 298-302 
    ISSN: 0031-8914
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica 2 (1935), S. 731-736 
    ISSN: 0031-8914
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica 2 (1935), S. 731-736 
    ISSN: 0031-8914
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 59 (1987), S. 73-82 
    ISSN: 1432-1246
    Keywords: Soil ingestion ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In recent years, many cases of soil pollution have been unearthed in the Netherlands. The ingestion of soil particles due to mouthing behaviour of young children is an important potential pathway of exposure and may constitute a health risk. For an assessment of these health risks, a reliable estimation of the daily inadvertent ingestion of soil particles is necessary. A method to estimate soil ingestion is the use of titanium (Ti), aluminium (Al) and acid insoluble residue (AIR) content of the soil as a tracer. By measuring these tracers in feaces of children and in soil, an estimate can be made of the amount of soil ingested. This method can be used if the following conditions are met: tracer intake by other routes (food) is low and not too variable; tracer absorption from soil in the gastro-intestinal (GI) tract is negligible; tracer concentrations in soil are high and not too variable. A small pilot study was conducted among 18 children visiting a nursery school and 6 hospitalized children without any possibility of soil contact. The results of the pilot study indicate that each tracer is present in faeces in highly variable amounts, but that a combination of these three tracers produces a useful picture of potential soil ingestion. Quantitatively, a difference between the two populations of 55 mg/d, expressed as soil ingestion, was found. Despite the small numbers involved, this difference was statistically significant as the population standard deviations were small. In a number of different soil types, tracer concentrations were found to be almost equal. Further studies are planned to test the validity of the assumptions, and to investigate larger child populations living in different circumstances.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 6
    ISSN: 1432-2072
    Keywords: Key words Amphetamine ; Pharmacokinetics ; Microdialysis ; Dopamine ; Rotational behavior ; Hyperthermia ; Brain temperature ; Unlesioned rats ; Individual differences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract It has been postulated that differences in pharmacokinetics do not contribute to the well-known individual variability in response to amphetamine (AMPH), but this is yet to be investigated thoroughly. Therefore, rotational behavior of outbred rats (Sprague-Dawley, 4 months old) was recorded during microdialysis sessions and striatal microdialysate was analyzed concomitantly for AMPH and dopamine concentrations after a single injection of 2.5 mg/kg AMPH SC. Three hours later these rats received three doses of 5 mg/kg AMPH SC (spaced 2 h apart) and their brain temperature was recorded every 20 min. The most important findings were: 1) the increase in extracellular dopamine was highly correlated with the corresponding peak AMPH levels in the microdialysate; 2) the peak dopamine level in response to 2.5 mg/kg AMPH was predictive of the hyperthermic response observed during 3 × 5 mg/kg AMPH and 3) high versus low rotators differed neither in their AMPH nor in their dopamine extracellular striatal concentrations.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 7
    ISSN: 1432-2072
    Keywords: Amphetamine ; Pharmacokinetics ; Microdialysis ; Dopamine ; Rotational behavior ; Hyperthermia ; Brain temperature ; Unlesioned rats ; Individual differences
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract It has been postulated that differences in pharmacokinetics do not contribute to the well-known individual variability in response to amphetamine (AMPH), but this is yet to be investigated thoroughly. Therefore, rotational behavior of outbred rats (Sprague-Dawley, 4 months old) was recorded during microdialysis sessions and striatal microdialysate was analyzed concomitantly for AMPH and dopamine concentrations after a single injection of 2.5 mg/kg AMPH SC. Three hours later these rats received three doses of 5 mg/kg AMPH SC (spaced 2 h apart) and their brain temperature was recorded every 20 min. The most important findings were: 1) the increase in extracellular dopamine was highly correlated with the corresponding peak AMPH levels in the microdialysate; 2) the peak dopamine level in response to 2.5 mg/kg AMPH was predictive of the hyperthermic response observed during 3 × 5 mg/kg AMPH and 3) high versus low rotators differed neither in their AMPH nor in their dopamine extracellular striatal concentrations.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 66 (1930), S. 471-476 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Es werden Formeln gegeben für die räumliche Verteilung der Moleküle, die durch eine kurze Röhre in ein leeres Gefäß einströmen. Unter Voraussetzung einer diffusen Zerstreuung an der Wand der Röhre und einer mittleren freien Weglänge, die groß ist gegenüber den Abmessungen der Röhre, ergibt die Rechnung schon im Falle, daß die Länge gleich dem Durchmesser ist, große Abweichungen von einer Strahlformung nach dem Kosinusgesetz. Die Mayerschen Experimente sind hiermit nicht im Einklang.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 9
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 56 (1929), S. 671-672 
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Zusammenfassung Es wird gezeigt, daß in der gleichnamigen Arbeit von Szilard ein Fehler enthalten ist, dessen Beseitigung das erhaltene Resultat hinfällig macht.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 10
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 160 (1927), S. 128-132 
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...