ISSN:
1432-1076
Keywords:
Childhood obesity
;
Hypertension
;
Hyperinsulinaemia
;
Sodium excretion
;
Norepinephrine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The aim of the present study was to evaluate the association between 24 h urinary excretion of sodium and blood pressure, fasting plasma insulin, renin, aldosterone and serum norepinephrine concentrations in 45 obese and 15 control children. Urinary sodium excretion was significantly lower in obese subjects (1.3 ±0.6 mmol/kg/24 h,P 〈 0.01) than in controls (2.8 ± 1.3 mmol/kg/24 h). Hyperinsulinaemia did not affect sodium excretion of obese children. Plasma renin and aldosterone levels did not correlate with sodium excretion and were significantly higher in overweight children. Serum norepinephrine levels were also significantly higher in the obese group (0.66 ± 0.89 μg/100 ml) as compared to the controls (0.11 ± 0.03 μg/100 ml,P 〈0.01) and showed significant negative correlation with urinary sodium excretion (r = 0.43,P 〈 0.05).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02282841
Permalink
