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  • 1
    Digitale Medien
    Digitale Medien
    Shear bond strength of resin teeth to heat-cured and light-cured denture base resin (2000)
    Oxford, UK : Blackwell Science Ltd
    Journal of oral rehabilitation 27 (2000), S. 0 
    Details
    ISSN: 1365-2842
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The failure of the bond between acrylic resin teeth and denture base material remains a considerable problem. Previous research has indicated that the introduction of a bonding agent to the tooth–resin interface significantly increased the tensile bond strength. To further investigate this finding, and to complement the earlier study, a shear strength assessment was carried out. Both a commercial and an experimental bonding agent were evaluated for tooth retention when applied to heat-cured and visible light-cured (VLC) resin. A significant increase in shear bond strength was obtained when bonding agents were applied. The experimental cement gave the greatest increase in strength, although the VLC resin failed to achieve the same degree of tooth attachment as the heat-cured resin.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1365-2842.2000.00522.x
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  • 2
    Digitale Medien
    Digitale Medien
    A new technique for determining the denture tooth bond (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 23 (1996), S. 0 
    Details
    ISSN: 1365-2842
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: summary Defective bonds between resin teeth and denture base material remain a continuing source of failure. Findings from the limited number of studies on this topic are diminished by the numerous experimental approaches adopted. National and international standard specifications also adopt different methods of specimen preparation and physical straining. A critical appraisal of the various standards is carried out and a new procedure for determining the denture tooth to acrylic resin bond is described. A study using this technique found that physical modification and alginate contamination of the tooth had no significant effect on the bond strength. Ineffectual wax elimination was the main cause of failure.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1111/j.1365-2842.1996.tb01234.x
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  • 3
    Digitale Medien
    Digitale Medien
    Surface roughness and wettability of enamel and dentine surfaces prepared with different dental burs (2001)
    Oxford UK : Blackwell Science Ltd
    Journal of oral rehabilitation 28 (2001), S. 0 
    Details
    ISSN: 1365-2842
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: The aim of dental adhesive restorations is to produce a long lasting union between the restoration and the tooth structure. This bond depends on many variables including the geometry of the preparation and the type of bonding agent or luting cement. It is therefore suggested that the topography of the tooth surface may influence the wettability and the bonding quality of adhesive systems. This study measured the surface roughness and wettability of enamel and dentine after preparation with different dental burs. The mesial and distal surfaces of 15 extracted sound human premolar teeth were prepared with a tungsten carbide crown bur, a diamond bur and a tungsten carbide finishing bur and finished in enamel or dentin, respectively. The prepared surfaces were analysed with a surface profilometer and scanning electron microscopy (SEM). The contact angle of distilled water on each of the prepared surfaces was used as the measure of wettability. The differences in average surface roughness (Ra) were significant between the rotary instrument groups, as revealed by a two-way ANOVA test. No differences were detected between enamel and dentine surfaces prepared with the same type of dental bur. The smoothest surfaces were those completed with tungsten carbide finishing burs. The diamond bur preparations were intermediate in the roughness assessment and the tungsten carbide crown burs gave the roughest surfaces. There were no significant differences in the contact angle measurements for the various groups. It was concluded that the surface roughness of enamel and dentine prepared by different rotary instruments had no significant influence on the wettabilty of distilled water on these surfaces.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1046/j.1365-2842.2001.00722.x
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  • 4
    Digitale Medien
    Digitale Medien
    Urinary D-glucaric acid excretion and acetanilide pharmacokinetics before and during diphenylhydantoin administration (1974)
    Springer
    European journal of clinical pharmacology 7 (1974), S. 387-391 
    Details
    ISSN: 1432-1041
    Schlagwort(e): Acetanilide ; diphenylhydantoin ; D-glucaric acid ; induction
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Summary The pharmacokinetics of a single-dose acetanilide (AA) test, and the urinary D-glucaric acid output (UDGAO) were studied in healthy drug free volunteer subjects before and at the end of a fourteen-day period of medication with 5 mg diphenylhydantoin sodium (DPH) per kg metabolically active mass, thrice daily. The steady state plasma concentration (SSPC) of DPH was also determined. The SSPC of DPH was found to vary from 3.4 to 19.6 µg per ml. The mean UDGAO values increased significantly during DPH medication from 9.5 µmol per g creatinine to 29.5 (p〈0.002). The half-life of plasma AA concentration decreased significantly during DPH medication from a mean of 4.2 h to a mean of 2.8 (p〈0.001). However, the plasma clearance of AA did not change significantly during DPH medication. The increase of UDGAO whilst on treatment with DPH correlated positively with the SSPC of DPH. The evidence from this study suggests that measurement of UDGAO, which is a measure of the activity of the glucuronic pathway does not necessarily indicate the state of induction of oxidizing enzymes in the hepatic endoplasmic reticulum.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00558212
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  • 5
    Digitale Medien
    Digitale Medien
    The pharmacokinetics of acetanilide and of diphenylhydantoin sodium (1974)
    Springer
    European journal of clinical pharmacology 7 (1974), S. 461-466 
    Details
    ISSN: 1432-1041
    Schlagwort(e): Acetanilide ; oxidation ; diphenylhydantoin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie , Medizin
    Notizen: Summary Acetanilide and diphenylhydantoin have a similar first stage biotransformation in that both are oxidized in the para position of the benzene ring incorporated in each of the two molecules. The elimination of acetanilide from the plasma was studied in thirty healthy volunteer subjects following a single oral dose of 50 mg per kg metabolically active mass (MAM = weight to the power of 0.7). Plasma clearance values varied from 12.4 to 25.11 per hour. A dose of 5 mg diphenylhydantoin sodium (DPH) per kg MAM was then given thrice daily for 13 days to the same volunteers. The steady state plasma concentrations of DPH varied from 3.4 to 19.6 µg per ml. Statistically significant correlation was demonstrated between plasma acetanilide clearance and DPH clearance (r=+0.4984). This finding suggests either a common enzyme acceptor or a common rate-limiting step in the metabolism of the two drugs. It is possible that the pharmacokinetics of other widely used drugs known to be oxidized, especially phenylbutazone, may also be correlated with the kinetics of acetanilide and of DPH. If this were so, then certain individuals might be at a relatively high risk (due to drug accumulation) of developing adverse effects from drugs metabolized mainly by oxidation, and certain other individuals who metabolize these compounds at a fast rate are likely not to derive therapeutic benefit. A single dose study with simple measurement of acetanilide pharmacokinetics could be used to identify these groups.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00560359
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