ISSN:
1432-1335
Keywords:
Benzo(a)pyrene
;
Caffeine
;
Oral administration
;
Tumors of the forestomach
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary In a lifetime experiment benzo(a)pyrene (B(a)P) was administered to Sprague-Dawley rats either as an admixture to the diet or by gavage in an aqueous 1.5% caffeine solution. Dissolved benzo(a)pyrene induced more tumors of the forestomach than undissolved benzo(a)pyrene. The 1.5% caffeine solution (annual dose 27 g/kg) did not exert any carcinogenic activity under the conditions of this bioassay.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00410666
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