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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 149 (1989), S. 136-137 
    ISSN: 1432-1076
    Keywords: Hypertensive crises ; Nifedipine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eight hypertensive crises (HC) were treated with 2.5 mg of sublingual nifedipine in three children with weights below 10 kg (group A); 16 HC in 6 children between 10 and 20kg with 5 mg (group B); and 40 HC in 10 children over 20kg with 10 mg of nifedipine (group C). The relative decrease in both systolic and diastolic blood pressure was similar in all groups. The decrease was more rapid in groups A and B when the contents were extracted from the capsule and given directly. The hypotensive effect lasted 4h. There were no side effects. The effective and safe single dose of nifedipine has been established to be 2.5 mg for children weighing less than 10 kg, and 5 mg for children weighing between 10 and 20 kg.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1238
    Keywords: Key words Intramucosal pH ; Gastric tonometry ; Tissue oxygenation ; Children ; Shock ; Monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To assess the efficacy of gastric intramucosal pH for the evaluation of tissue perfusion and prediction of hemodynamic complications in critically ill children. Design: Open prospective study without controls
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 23 (1997), S. 218-225 
    ISSN: 1432-1238
    Keywords: Key words Cost ; Cost analysis ; Variable cost ; Pediatric intensive care
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To analyze the actual cost of pediatric intensive care and its different components, particularly the differences between various patient groups, with special reference to the variable cost and the elements included in it. Design: Prospective, observational study. Setting: Multidisciplinary 12-bed pediatric intensive care unit (PICU) in a tertiary university hospital. Patients: 495 admissions to the unit over 17 consecutive months; 64.2 % were medical patients and 35.8 % were surgical patients; the mean (SE) stay in the PICU was 6.6 ± 0.4 days. Measurements and results: The fixed cost per day per patient was calculated, including the costs of physicians, nurses, auxiliary and other personnel who worked during the study period, and the costs of structural depreciation, maintenance, consumption, and disposable material. The variable cost was individually calculated from the costs of routine procedures and also included expenditure on pharmaceuticals, blood products, biochemical, hematological, and bacteriologic tests, radiology, image diagnosis procedures, and other procedures. The Physiologic Stability Index (PSI) was obtained in the first 24 h after admission. The mean fixed cost per patient per day was u. s. $ 608, which represents 72 % of the total patient cost during this study; 86 % of this amount was for personnel (58 % for nurses and auxiliary staff). Variable costs came to 28 % of the total amount, and were $ 218 ± 100 (M± SEM) per patient per day. In addition to the costs of their longer stay in the PICU, the daily variable costs of nonsurvivors were higher than those of survivors ($ 542 ± 52 vs $ 179 ± 7; p 〈 0.001). We classified the patients into four groups according to their PSI score in the first 24 h; variable daily costs increased (p 〈 0.05) in all comparisons with the PSI level: group I: 〈 4 points ($ 155 ± 0.5), group II: 5–9 points ($ 210 ± 13), group III: 10–14 points ($ 324 ± 54), group IV: 〉 15 points ($ 480 ± 42). However, this pattern was not found for all resources: the cost of treatment techniques and biochemical and hematological tests increased, but the consumption of antibiotics, parenteral nutrition, blood products, and bacteriologic tests reached their maximum level in groups I–III and radiology was not significantly influenced by PSI level. Conclusions: The cost of personnel was the biggest factor in intensive care costs: 62.4 % of the total costs. Nonsurvivors generated 3 times the mean variable daily expenditure on survivors and had longer stays in the PICU. The increase in PSI score on the first day was associated with a global increase in variable costs. The cost of treatment techniques significantly increased as the illness became more severe but consumption of antibiotics and parenteral nutrition and use of bacteriologic tests and radiology did not.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 15 (1989), S. 224-227 
    ISSN: 1432-1238
    Keywords: Continuous arteriovenous haemofiltration ; Acute renal failure ; Hypervolaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Continuous arteriovenous haemofiltration (CAVH) was used in 7 critically ill children: a premature neonate with hypervolaemia secondary to hydrops foetalis and six children aged 9 days to 7 years with acute oliguric renal failure. Biospal 0.5 m2, Renaflo 0.25 m2, Gambro 0.15 m2 and Amicon 0.015 m2 filters were used according to the weights and ages of the patients. Adequate removal of water and solutes was obtained in 6 patients. One of the patients with the smallest filter needed a change to a filter with a larger surface area to improve water and solute removal. Haemofiltration was maintained for between 17 hours and 31 days and was well tolerated. CAVH was discontinued because of recovery of renal function in three patients, improvement of the hypervolaemic state in one, death in three, and transfer to continuous ambulatory peritoneal dialysis because of chronic renal failure in one patient. CAVH is a useful technique for the treatment of acute renal failure and hypervolaemia in critically ill children.
    Type of Medium: Electronic Resource
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