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  • 1
    ISSN: 1432-1084
    Keywords: Key words: Magnetic resonance imaging ; Magnetization transfer contrast ; Gadolinium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Magnetization transfer (MT) provides post-gadolinium contrast improvement through decreasing the tissue signal. Our study had two aims: to analyse the effect of MT qualitatively and quantitatively in 13 patients, and to analyse in vitro the competition betwen two relaxation phenomena, dipole-dipole which is characteristic of MT and proton – electron which is characteristic of gadolinium. Contrast between lesion and white matter improved from 20.6 % before MT to 65.1 % after MT, enabling new lesions to be detected in two patients. The improvement was due mainly to the proton – electron effect of gadolinium rather than the dipole relaxation of MT. These results are in agreement with those in the literature. The existence of spontaneous high-signal induced by MT in the absence of gadolinium indicates that it is preferable to perform an MT sequence before and after administration of gadolinium.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1084
    Keywords: Computed tomography ; High osmolar contrast media complications ; Risk factors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A prospective study was conducted from February 1989 to January 1991, on 5,000 consecutive patients, undergoing CT studies of the head and brain, to evaluate the adverse reactions to sodium meglumine ioxithalamate, a high-osmolar contrast medium (HOCM). The overall incidence of moderate or severe reactions was 2.8%. Severe reactions occurred in 0.06% and moderate reactions in 2.74% of the contrast media examinations. It is interesting to note that the risk of adverse reactions was multiplied by 7.6 in patients with the acquired immune deficiency syndrome (AIDS). No deaths occured. It is concluded that the incidence of adverse reactions to Ioxithalamate is low. Although the occurrence of adverse reactions is lower with low osmolar contrast media (LOCM), the routine use of HOCM appears justified by the best cost-efficacy ratio in low-risk patients.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1920
    Keywords: Key words Magnetic resonance imaging ; Magnetisation transfer ; Magnetisation transfer ratio ; Multiple sclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Magnetisation transfer (MT) is a recently introduced technique for assessing the water content of tissues in vivo and its relationship to macromolecules or membranes. It has been suggested that MT could provide indirect evidence of the characteristics of multiple sclerosis (MS) lesions (oedema, demyelination, or gliosis). Our aims were to characterise brain MS lesions and to compare the magnetisation transfer ratio (MTR) values of lesions with different patterns of contrast enhancement. In patients with MS we measured the MTR of 65 gadolinium-enhancing and 292 nonenhancing lesions. Using the equation published by Dousset et al. we studied 29 patients with clinically definite MS and 10 healthy controls. Lesions had significantly lower MT than the normal-appearing white matter of the patients or the normal white matter of healthy controls. There was no difference in the MTR of enhancing and nonenhancing lesions. Enhancement was homogeneous in 45 and ring-like in 20 lesions; MTR values were lower in the latter. These findings are presumably related to the differences in pathological features of enhancing (different amounts of proteins and inflammatory cells, oedema and demyelination) and nonenhancing (gliosis, demyelination and axonal loss) lesions.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1920
    Keywords: Key words Aneurysmal bone cyst ; Raised intracranial pressure ; Bone tumour ; Skull
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aneurysmal bone cysts in the skull vault are reported in two patients 7 and 9 years old, who presented with vomiting and headaches caused by raised intracranial pressure. CT showed the cystic lesion in the diplo%e, with predominantly inward expansion. Fluid-fluid levels were seen on both CT and MRI; the latter also showed bleeding within the cyst. MR angiography showed compression of the superior sagittal sinus in the second case.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 41 (1999), S. 785-787 
    ISSN: 1432-1920
    Keywords: Key words Pituitary adenoma ; Metastases ; subarachnoid ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Few cases of pituitary adenoma with metastases have been reported. We report a case with histologically benign intracranial and cauda equina metastases. We compare it to the others in the literature.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1920
    Keywords: Vertebral haemangioma ; Interventional radiology ; Vertebroplasty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a 17-year-old asymptomatic patient with a partially collapsed seventh cervical vertebra due to a haemangioma revealed by conventional radiographs performed for army enrolment. Given radiological evidence of aggressiveness, percutaneous vertebroplasty by injection of methyl meth-acrylate cement was performed to prevent complications. CT a year later showed no progression of the lesion. The patient remains asymptomatic.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-1920
    Keywords: Magnetic resonance imaging techniques ; Magnetic resonance angiography ; Magnetisation transfer contrast
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To improve 3D-time of flight (3D-TOF) magnetic resonance angiography, we used magnetisation transfer (MT) to increase the contrast between flowing blood and stationary tissues. With a 1.5 KHz off-resonance radio-frequency MT applied for 16 ms at a maximum power within specific absorption rate (SAR) limits, a 37% decrease in the signal of white matter was obtained, whereas the signal from flowing blood decreased by only 8%. An improvement in maximum intensity projection (MIP) image quality was obtained all MT-3DTOF studies on seven volunteers using progressively more powerful MT pulses. Routine clinical use of MT-3DTOF appears promising and can be achieved at any strength field.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1920
    Keywords: Magnetic resonance imaging ; Magnetisation transfer ; Magnetisation transfer ratio ; Multiple sclerosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Magnetisation transfer (MT) is a recently introduced technique for assessing the water content of tissues in vivo and its relationship to macromolecules or membranes. It has been suggested that MT could provide indirect evidence of the characteristics of multiple sclerosis (MS) lesions (oedema, demyelination, or gliosis). Our aims were to characterise brain MS lesions and to compare the magnetisation transfer ratio (MTR) values of lesions with different patterns of contrast enhancement. In patients with MS we measured the MTR of 65 gadolinium-enhancing and 292 nonenhancing lesions. Using the equation published by Dousset et al. we studied 29 patients with clinically definite MS and 10 healthy controls. Lesions had significantly lower MT than the normal-appearing white matter of the patients or the normal white matter of healthy controls. There was no difference in the MTR of enhancing and nonenhancing lesions. Enhancement was homogeneous in 45 and ring-like in 20 lesions; MTR values were lower in the latter. These findings are presumably related to the differences in pathological features of enhancing (different amounts of proteins and inflammatory cells, oedema and demyelination) and nonenhancing (gliosis, demyelination and axonal loss) lesions.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1920
    Keywords: Key words Vertebral haemangioma ; Interventional radiology ; Vertebroplasty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a 17-year-old asymptomatic patient with a partially collapsed seventh cervical vertebra due to a haemangioma revealed by conventional radiographs performed for army enrolment. Given radiological evidence of aggressiveness, percutaneous vertebroplasty by injection of methyl methacrylate cement was performed to prevent complications. CT a year later showed no progression of the lesion. The patient remains asymptomatic.
    Type of Medium: Electronic Resource
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