ISSN:
1432-0703
Source:
Springer Online Journal Archives 1860-2000
Topics:
Energy, Environment Protection, Nuclear Power Engineering
,
Medicine
Notes:
Abstract Five bulked human adipose tissue samples were analyzed for individual polychlorinated biphenyl (PCB) congeners (including selected non-ortho-substituted compounds) and polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs). Mean ΣPCB and ΣPCDD/F (tetra-through octachlorinated homologues) concentrations were 0.75 μg/g and 1.22 ng/g adipose tissue respectively. Both the congener patterns and levels detected were similar to those reported by laboratories in other industrialised countries. Each sample comprised of tissue taken from donors within a given locality. However, no obvious relationships were apparent between sampling area, absolute concentrations and congener pattern of PCBs and PCDD/Fs. The contribution of individual PCDD/F and non -ortho-(o), mono-o-, and di-o-substituted PCB congeners to the total calculated toxic equivalent values (ΣTEQ) was assessed for each sample. The main contributions to the ΣTEQ were the mono-o-substituted PCB congeners #118 (TEQ=42.5 pg/g of lipid), #156 (TEQ=24.8 pg/g) and #105 (TEQ=20.7 pg/g), followed by 1,2,3,6,7,8-HxCDD (TEQ=18.2 pg/g), 2,3,4,7,8-P5CDF (TEQ= 12 pg/g), 1,2,3,7,8-P5CDD (TEQ=11.5 pg/g), and the non-o-substituted PCB congener #126 (TEQ =11.3 pg/g). Collectively, these compounds accounted for 80% of the STEQ values. Based on the TEFs proposed by Safe (1990), the overall TEQs calculated for the monitored PCBs, were twice those due to ΣPCDD/Fs.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01061096
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