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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 683 (1993), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 683 (1993), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Clinical and experimental medicine 151 (1969), S. 89-92 
    ISSN: 1591-9528
    Keywords: Hexacyanoferrate(II) ; Thallium ; Rat ; Hexacyanoferrat(II) ; Thallium ; Ratte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die orale Verabfolgung der kolloidalen Fe(III)-, Co(II)- und Ni(II)-Hexacyanoferrate(II) bewirkt eine starke Herabsetzung der Retention von oral oder intravenös verabreichtem Thallium(I) durch die Organe der Ratte. Die Effektivität ist höher als die des sogenannten unlöslichen Berliner Blau.
    Notes: Summary Oral administration of colloidal Fe(III)-, Co(II)- and Ni(II)-hexaoyanoferrates(II) leads to a markedly diminished retention of orally or intravenously administered thallium(I) by the organs of the rat. The efficacy surpasses that of the so-called insoluble Prussian Blue.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Clinical and experimental medicine 152 (1970), S. 352-355 
    ISSN: 1591-9528
    Keywords: Aurothiomalate ; Penicillamine ; Diethylenetriaminepentaacetate ; Rat ; Aurothiomalat ; Penicillamin ; Diäthylentriaminpentaacetat ; Ratte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurde der Einfluß der D- und L-Isomeren von Penicillamin sowie von Diäthylentriaminpentaacetat auf die Organverteilung von Gold bei der Ratte untersucht. Während Diäthylentriaminpentaacetat sich als unwirksam erwies, wird Gold durch Penicillamin in nur geringem Maße mobilisiert. Der klinische Wert von Penicillamin als mögliches Antidot bei der Chrysotherapie erscheint somit fraglich.
    Notes: Summary The influence of the D- and L-isomeres of penicillamine as well as of diethylenetriaminepentaacetate on the distribution of gold in the organs of the rat was studied. Whereas diethylenetriaminepentaacetate proved to be ineffective, penicillamine brings about a marginal mobilization of gold only. The clinical value of penicillamine as possible antidote in chrysotherapy, therefore, is doubtful.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 269 (1971), S. 48-56 
    ISSN: 1432-1912
    Keywords: Colloidal Ferrihexacyanoferrate(II) ; Potassium Hexacyanoferrate(II) ; Metabolism ; Toxicity ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Intestinal absorption, distribution, and excretion of ferrihexacyanoferrate(II), labeled by59Fe at the Fe(III)- and Fe(II)-atoms, respectively, was studied in rats. Following i.v. injection, the compound is separated at ∼60% into Fe3+ and [Fe(CN)6]4−, the residual fraction being retained by the reticuloendothelial system. [Fe(CN)6]4− is excreted rapidly and virtually completely by the kidneys. With oral administration the disintegration amounts to ∼7%, and ∼2% of [Fe(CN)6]4− is absorbed from the gut. No evidence was obtained for decomposition of [Fe(CN)6]4−. No toxic side-effects were observed after chronic administration of ferrihexacyanoferrate(II).
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 162 (1974), S. 63-66 
    ISSN: 1433-8580
    Keywords: Rhyolithic pumice ; Ferrihexacyanoferrate (II) ; Thallium ; Rat ; Rhyolithischer Bims ; Ferrihexacyanoferrat (II) ; Thallium ; Ratte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Orale Verabfolgung von rhyolithischem Bims bewirkt eine herabgesetzte Retention von Thallium in den Geweben. Die Wirksamkeit von Rhyolith zeigt eine ausgeprägte Dosisabhängigkeit, ist aber geringer als die von Ferrihexacyanoferrat (II).
    Notes: Summary Oral administration of rhyolith leads to a diminished retention of thallium by the tissues. The effectiveness of rhyolith markedly depends on its dosage, but is surpassed by that of ferrihexacyanoferrate (II).
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-136X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Effects of photoperiod, temperature and food and water availability on body and testicular mass of golden hamsters were investigated. Lack of water or food inhibited body growth. Short photoperiod (LD 8:16) enhanced boyd growth in males fed ‘poor diet’ but it had no effect in animals on ‘high quality diet’. Cold exposure diminished body growth in animals with access to water but not in those deprived of water. It is suggested that lowered motor activity is mainly responsible for body mass gain of animals kept under the short photoperiod. All stressful factors (water deprivation, ‘poor diet’ or cold) induced involution of testes. The time course of testicular involution was similar to that induced by short photoperiod. Testicular involution was, after several weeks, followed by spontaneous recrudescence. Combination of stressful external cues speeded up testicular involution. Since the testicular involution induced by water deprivation, “poor diet” and cold also occurred in animals kept in constant light or under long photoperiod (which are known to produce functional pinealectomy) it is concluded that the inhibitory effects of stressful external factors on testes are not mediated by the pineal. The decrease in testosterone production induced by external cues precedes changes in testicular mass. In individuals kept in the cold, testosterone production remains low, in spite of spontaneous recrudescence of the testes. No simple relationship between testosterone concentration in the blood and testicular mass was observed. The mass of the interscapular brown adipose tissue (ISBAT) changes strikingly during the hibernation cycle. Immediately after exposure to cold it decreases and stays at the low level for 40 days. Than it increases markedly and reaches maximum after 90 days, when hibernation progresses. During the hibernation season the mass of the ISBAT decreases. Constant darkness enhances the cold-induced growth of the ISBAT only at the beginning of the hibernation season.
    Type of Medium: Electronic Resource
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