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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Immunogenetics 25 (1987), S. 299-304 
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract In this article we present a study showing that the human C4 genes differ in length because of the presence or absence of a 6.5 kb intron near the 5′ end of the gene. DNA from individuals of known HLA, factor B, and C4 haplotypes was analyzed for restriction fragment length polymorphism (RFLP) by Southern blot analysis with C4-specific cDNA probes. The RFLP patterns obtained showed that the C4 genes are either 22.5 kb or 16 kb in length. They are referred to as long and short C4 genes, respectively. A population study was carried out to examine the distribution of the gene size according to C4 allotypes and haplotypes. Long C4 genes included all C4A genes studied and also some C4B allotypes, e. g., B1 on most C4 A3B1 haplotypes. Similarly, C4B null genes were found to be of the long form. Other C4B allotypes tested were found to be coded for by short C4 genes, including B2, B1 in C4 A6B1 and C4 AQOB1 (with a single C4B gene haplotype).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Immunogenetics 21 (1985), S. 39-48 
    ISSN: 1432-1211
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Factor B and the second component of complement (C2) in man are encoded within the major histocompatibility complex by single loci that are less than 1 kb apart. A 2.3 kb factor B-specific cDNA probe has been used to examine, by Southern blot analysis, the genomic DNA of individuals typed for C2 and factor B by protein electrophoresis. We have identified a restriction fragment length polymorphism using the endonuclease Taq I, which subdivides haplotypes carrying both the common variant of C2 (C2C) and the fast (F) variant of factor B. This DNA polymorphism has been mapped to lie in the C2 gene and represents a new genetic marker not defined by protein electrophoresis. This polymorphism may serve as a useful marker in the genetic analysis of diseases that are related to the major histocompatibility complex.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0789
    Keywords: Key words Newsprint ; Woodchips ; Cotton gin waste ; Yard waste ; Poultry liter ; Mineralization ; Microbial ; biomass ; Cellulose degradation ; Soil fertility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract We assessed the influence of the addition of four municipal or agricultural by-products (cotton gin waste, ground newsprint, woodchips, or yard trimmings), combined with two sources of nitrogen (N), [ammonium nitrate (NH4NO3) or poultry litter] as carbon (C) sources on active bacterial, active fungal and total microbial biomass, cellulose decomposition, potential net mineralization of soil C and N and soil nutrient status in agricultural soils. Cotton gin waste as a C source promoted the highest potential net N mineralization and N turnover. Municipal or agricultural by-products as C sources had no affect on active bacterial, active fungal or total microbial biomass, C turnover, or the ratio of net C:N mineralized. Organic by-products and N additions to soil did not consistently affect C turnover rates, active bacterial, active fungal or total microbial biomass. After 3, 6 or 9 weeks of laboratory incubation, soil amended with organic by-products plus poultry litter resulted in higher cellulose degradation rates than soil amended with organic by-products plus NH4NO3. Cellulose degradation was highest when soil was amended with newsprint plus poultry litter. When soil was amended with organic by-products plus NH4NO3, cellulose degradation did not differ from soil amended with only poultry litter or unamended soil. Soil amended with organic by-products had higher concentrations of soil C than soil amended with only poultry litter or unamended soil. Soil amended with organic by-products plus N as poultry litter generally, but not always, had higher extractable P, K, Ca, and Mg concentrations than soil amended with poultry litter or unamende soil. Agricultural soil amended with organic by-products and N had higher extractable N, P, K, Ca and Mg than unamended soil. Since cotton gin waste plus poultry litter resulted in higher cellulose degradation and net N mineralization, its use may result in faster increase in soil nutrient status than the other organic by-products and N sources that were tested.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 682 (1993), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 615 (1991), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Studies of 521 sera from the Icelandic cousin marriage project were made to assess the incidence of various anti-tissue antibodies and the levels of immunoglobulins, as these were considered to be useful markers of the humoral immune response. Comparisons were made between these parameters and the HLA-A and B antigens, the blood groups, the immunoglobulin allotypes (Gm, Km and Am), the properdin factor (Bf), and other markers.These investigations offered another approach to the study of the sites of action of immune response genes in man. Because the immune response may be expected to differ for each individual and depend at least in part, on the degree of exposure to different antigens, no absolute correlation was expected. There was, however, a marked association between certain IgG anti-tissue antibodies and HLA antigens. This was most marked for HLA-A10, B18 and B27, but not for HLA-A1 or B8.The comparison of immunoglobulin levels with HLA antigens, was less striking, although HLA-A2 appeared to be associated with low levels of IgE. There were also some associations between immunoglobulin levels and ABO blood groups.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 13 (1986), S. 0 
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Book Review in this articleM. W. Strickberger: Genetics. Collier Macmillan, New York, London. 1985. ISBN 0-02-418120-X. Price £l5.95.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 1 (1974), S. 0 
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Some problems in the detection and estimation of associations between multiallelic systems, such as HL-A, and disease are discussed and a simple, but slightly conservative, method of analysis is advanced which allows a simple method of display.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 199 (1963), S. 1114-1115 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Nor have there been any major advances in the past four years which either simplify or accelerate mitotic investigations on post-mortem material; these are still dependent on the skilled and laborious ritual of fibroblast culture. Lymphocyte cultures obtained by briefly dipping an intact thymus in ...
    Type of Medium: Electronic Resource
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