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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 8 (1981), S. 0 
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract Citric acid conditioning of the root surface as a supplement to replaced flap surgery of intraosseous periodontal defects was evaluated, Thirteen patients and a total of 45 proximal defects with residual probing pocket depth ≥ 6 mm after initial preparation were used. The effect of treatment was studied in matched subsamples of the total material including one acid-treated and one nonacid-treated defect from each subject, The results demonstrated that an average gain of probing attachment level amounting to 2.0 mm was obtained following acid treatment as compared to 1.l–1.2 mm for the nonacid-treated controls. Corresponding figures for gain of probing bone level were 1.2–1.3 mm for acid treatment and 0.8–0.9 mm for controls. The clinical significance of these findings was discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of clinical periodontology 17 (1990), S. 0 
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract A biodegradable polylactic acid membrane was evaluated for its ability to enhance periodontal regeneration. In 8 Labrador dogs, circumferential defects were created around the maxillary 1st premolars. The defects were combination “1-wall vertical and horizontal”. A membrane was adjusted to cover the defect on one side of the jaw, while the contralateral tooth served as control without membrane. After 3 months, healing was evaluated histologically. The results demonstrated that the amount of connective tissue repair with newly formed cementum approximated 50% of the defect height for both test and control groups. Thus, no advantage to the use of membrane was found, which is contradictory to the findings of our previous dog study using the same biodegradable membrane. The possible reasons for this difference in results are discussed relative to suggested mechanisms for membrane effects in periodontal regeneration.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 9 (1974), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The daily post-operative use of topical chlorhexidine application has been compared to daily toothbrushing. Periodontal defects were experimentally created in the bifurcations of lower premolars in dogs. The defects were treated by surgical debridment. Chlorhexidine application and toothbrushing were performed post-operatively for six weeks on contra-lateral pairs of teeth. The amounts of connective tissue and bone regeneration were evaluated from microscopic sections of the bifurcation areas. No difference between chlorhexidine and toothbrushing was found for the connective tissue attachment. However, significantly more bone had regenerated in the chlorhexidine treated areas than the tooth-brushed areas.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 16 (1981), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 16 (1981), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Periodontal furcation pockets were created in mandibular premolar teeth of three beagles and subsequently treated by reconstructive procedures including flap surgery, root planing and application of citric acid. Block biopsies removed after 1, 2, 3 and 6 weeks showed new attachment of connective tissue to the periodontally involved root surface. This was established by progressive interdigitation of new collagen fibrils and the acid-exposed fibrils of the dentin matrix along the root planed surface as well as within the orifice of dentinal tubules. The results supplement those of a previous study (Ririe, Crigger & Selvig 1980) and show that attachment of soft connective tissue to a root planed and acid-conditioned dentin surface can be achieved by the same mechanism irrespective of whether the root surface has been surgically denuded or has been exposed to the environment of an experimental periodontal pocket.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 15 (1980), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A study was made to investigate the biological principle of new attachment of connective tissue to periodontally diseased root surfaces utilizing the previous finding that topical application of citric acid to the affected area may stimulate periodontal regeneration. Reconstructive surgery was performed on ten surfaces of nine teeth involved in advanced chronic periodontal disease. A muco-periosteal flap was raised and the apical extent of existing subgingival calculus was demarcated by a notch made through the calculus and into the root. Following thorough instrumentation, a saturated solution of citric acid was applied to the root surface for five minutes and the flap repositioned and sutured. Four months later the teeth with attached periodontal tissues were removed and processed for histological analysis. Connective tissue regeneration characterized by deposition of new cementum, and more coronally, by tightly apposed soft connective tissue had occurred in all specimens. The junctional epithelium ended 1.2–2.6 mm coronal to the apical border of the notch in the various specimens. The results demonstrate that regeneration of periodontal tissues to a root surface that has become denuded as a result of chronic, destructive periodontal disease and that has been covered by calculus is, in fact, a biological possibility. This study does not establish whether or not acid conditioning of the root surface is a prerequisite for new attachment.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 20 (1985), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The effect of a periodontal flap procedure, that included citric acid root conditioning and closure of the wounds by suturing of coronally elongated flaps, was studied in mandibular premolars and molars in monkeys. Three months in advance, to prepare for this regenerative procedure, every other tooth in the mandibular posterior segments was extracted and the alveolar bone level reduced to a level approximately 5 mm apical to the cemento-enamel junction around the remaining teeth. Histologic observations of biopsies removed 6 months after the regenerative surgery disclosed resorption of the treated root surfaces in the majority of specimens. Citric acid treatment of the root surfaces cannot have been primarily responsible for the resorption, as control surfaces, on which acid was not used, also displayed resorption. Resorption occurred most commonly on surfaces in which the junctional epithelium showed limited apical migration and was located 2 mm or more coronal to the apical extent of root planing.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 15 (1980), S. 0 
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In a previous study, citric acid-conditioning of the root surface greatly improved the rate of success of new-attachment procedures in periodontal furcation pockets in mandibular premolars of Labrador retrievers (Crigger et al. 1978). In the present study, this experimental approach was tested in six beagles. The furcations on one side in each dog were reoperated six weeks after the first surgery. In 27 of the 35 treated teeth, mesiodistal sections showed closure of the furcation and new connective tissue attachment including deposition of new cementum. The extension of new attachment in the buccolingual dimension of the furcation, however, was not improved by repeating the surgical procedure.
    Type of Medium: Electronic Resource
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