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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 100 (1993), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To compare reagent strip testing (RST) with microscopy and culture in identifying significant bacteriuria, and secondly, to consider potential cost savings if RST screening proved to be reliable.Design Prospective descriptive study.Setting Antenatal Clinic, Bristol Maternity Hospital.Subjects Eight hundred and ninety-eight women having urine testing in pregnancy for microscopy and culture either routinely or because of a clinical indication.Interventions The midstream specimens of urine had RST examination using Ames Multistix 8SG prior to being sent to the laboratory.Main outcome measure Significant culture (〉105 colonies/ml) of a single organism in culture.Results The highest predictive value for a negative result of the urine culture (99.7%) was obtained when using four RSTs in combination. The RST for nitrite had a high predictive value for a positive urine culture (90%). The samples which gave a false negative result with RST screening were mainly infected with low grade urinary pathogens or genital tract contaminants.Conclusion RST screening for bacteriuria provides a reliable and cheap alternative to culture of all urine specimens.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 104 (1997), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To assess the diagnostic accuracy of a new technique of cervical imaging and to consider its potential as a secondary cervical screening method.Design A prospective cross-sectional study with each case acting as its own control, comparing video colpography with colposcopy.Setting University of Birmingham colposcopy clinics, City Hospital and Birmingham Women's Hospital.Participants Fifty women referred for colposcopy.Interventions The women had a video colpogram recording made prior to colposcopy.Main outcome measures The proportion of technically suitable colpograms obtained and the level of agreement between colposcopist and video screener.Results The images were satisfactory or good in 94% cases, and there was a very high level of agreement between colposcopist and video screener (K = 0.79). If the technique had been used in a primary health care setting as a secondary screening method for women with low grade cervical smear abnormalities, 61% would have avoided referral for colposcopy.Conclusions Video colpography is an accurate, portable and quick method of cervical imaging. It combines the simplicity of a video camera with the versatility of computerised digital imaging and has great potential in the fields of teaching, audit and screening of low grade smear abnormalities.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 104 (1997), S. 0 
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To assess variation in diagnoses and management decisions among colposcopists when presented with cervical images; to see the impact of the referral cytology report on diagnostic accuracy.Design A two-part video questionnaire study.Participants Colposcopists from West Midlands RegionMethods Twenty cervical images displaying a range of transformation zones from normal through varying abnormalities up to cervical intraepithelial neoplasia (CIN) grade 3 were shown on video tape together with basic patient information. Two sets of videos were made, the second being identical to the first other than including the referral cytology. Participants recorded their diagnoses and management decisions on prepared questionnaires. The two sets of videos were viewed several weeks apart.Results Completed questionnaires to both videos were received from 30 colposcopists. Diagnostic accuracy improved with knowledge of the cervical cytology result in cases of CIN 2/3 (x2= 19.45, P 〈 0.0001) but not where the histology was CIN 1 or less (x2= 2.64, P= 0.10). Overall inter-observer agreement improved slightly from K = 0.169 to K = 0.212 when the cytology was revealed. While only 2.6% of cases of CIN 2/3 would have been under-managed after the second questionnaire, 37.5% cases where the abnormality did not amount to CIN would have been over-treated.Conclusion There is considerable inter-observer variability and variation in diagnostic accuracy in scoring cervical images particularly at the lower end of the spectrum of abnormality which has the potential to lead to over-treatment. We rely considerably on the cervical cytology result in forming a diagnosis. We recommend that a see-and-treat approach be abandoned when the referral smear shows minor abnormalities. The study has implications for both training and audit in colposcopy
    Type of Medium: Electronic Resource
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