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  • 1
    ISSN: 1365-2826
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: To investigate the physiological regulation of luteinizing hormone (LH) secretory events and the endogenous clearance of this hormone, we applied multiple-parameter deconvolution analysis to serum LH concentration-time series obtained from normal women during three phases of the menstrual cycle. The number of significant LH secretory bursts (/24 h) was maximal in the late follicular (LF) phase (27 ± 1.6; mean ± SEM), minimal in the mid-luteal (ML) phase (10 ±1.0) and intermediate in the early follicular (EF) phase (18 ± 1.4). Similarly, the half-duration of the secretory impulse (min) was different at each phase of the cycle with values of 6.5±1.0, 3.5±0.9 and 11 ± 1.1 during the EF, LF and ML phases, respectively. In contrast, there were no cycle-dependent differences in the LH half-life or in the total daily secretion of LH.When maximal secretory impulse amplitudes were examined, a putative bimodal distribution was found in the ML but not the EF or LF phases. The amplitudes for the large ML impulses, the LF and EF impulses and the small ML impulses were 0.95 ± 0.05, 070 ± 0.03, 0.43 ± 0.02 and 0.26 ± 0.02, respectively. The mass (mlU/ml) of hormone secreted within bursts was minimal in the LF phase (2.1 ± 0.1), maximal in the large ML impulses (10.2 ± 0.5) and intermediate in the EF (2.8 ± 0.1) and small ML (3.1 ±0.3) secretory impulses.There was no evidence of tonic (i.e. inter-secretory burst) LH secretion during any phase of the menstrual cycle. The early morning hours of the EF phase were characterized by fewer secretory bursts of greater amplitude. During the ML phase, autocorrelation analysis of inter-secretory burst intervals revealed a negative association indicating that high frequency events both precede and follow secretory pauses. In addition, secretory burst amplitude and both the preceding and following inter-secretory burst interval was correlated to secretory burst amplitude.These new data on the nature of regulated LH secretion indicate that specific facets of spontaneous LH secretory events are controlled throughout the menstrual cycle. Such observations offer a basis for defining altered secretory dynamics in a variety of pathophysiologic situations.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Parasitology research 38 (1972), S. 147-151 
    ISSN: 1432-1955
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary The present report deals with a study of the osmoregulation of young Hymenolepis microstoma using the in vitro cultivation at different osmotic pressures: i.e. in eleven media with freezing point depressions ranging from 0.35 to 1.21° C. It has been shown that H. microstoma is able to develop optimally and equally well in media with freezing point depressions from 0.50 to 0.73° C. The worm seems to have a regulatory system operating successfully between these approximate limits. Media with lower or higher osmotic pressures do not cause death within the present experimental conditions but inhibit development gradually. It is concluded that, although cestodes are regarded as poikilosmotic, the present results with H. microstoma indicate that homoiosmotic properties might exist within a certain limited range of osmotic pressures.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Archives of sexual behavior 14 (1985), S. 327-342 
    ISSN: 1573-2800
    Schlagwort(e): vaginal pulse amplitude ; female sexual arousability ; stage REM arousal ; sexual response
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Psychologie
    Notizen: Abstract Vaginal photoplethysmography has been used to investigate sexual arousal response patterns in small samples of sexually functional and dysfunctional women, but selection of subjects for these studies has not been of a standardized nature. In the present study, two groups of women, who placed in either the upper or lower percentile ranks on the Sexual Arousal Inventory (Hoon et al., 1976a), were compared on a physiological measure of sexual arousal, vaginal pulse amplitude (VPA), during both waking erotic conditions and sleep. As hypothesized, no differences in VPA were found between groups during either waking or sleeping conditions. Contrary to expectation, groups also did not differ on subjective ratings of their laboratory arousal. With both groups combined, differences in VPA levels were evident between baseline and erotic conditions. Similarly, VPA levels differed between stages of sleep, with highest levels observed during rapid-eye-movement (REM) sleep. These findings suggest that self-reported low arousability is not based on lack of physiological response and that retrospective, self-report measures of sexual arousability differ in important ways from subjective and physiological measures of sexual arousal in the laboratory. In order to adequately assess sexual arousability, future researchers must either devise laboratory conditions that more closely resemble erotic stimuli occurring in subjects' natural environments or validate physiological measures of arousal in nonlaboratory settings. Finally, the nocturnal evaluation of VPA seems potentially useful for cases in which organic factors may be contributing to sexual dysfunction.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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