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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 86 (1964), S. 5370-5371 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 88 (1966), S. 2759-2766 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1440
    Keywords: Undifferentiated sarcoma ; Embryonal sarcoma ; Heart ; Brain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 26-year-old woman with a tumor of the left liver lobe was admitted to the hospital. After incomplete resection of the tumor and histological diagnosis of an undifferentiated (embryonal) sarcoma of the liver a combination chemotherapy with ifosfamide and epidoxorubicine was started. 11 months later brain metastases were diagnosed. Routine ultrasound examination of the heart disclosed a pericardial tumor infiltrating the left atrium of the heart. After radiation therapy of the brain metastases the patient was treated with two cycles of high-dose ifosfamide and epidoxorubicin. Two years after diagnosis the patient developed signs of cardiac failure and died. Postmortem autopsy confirmed the local recurrence of the liver neoplasm and revealed its continuous spread to the pericardium via the diaphragm and infiltration of the left atrium.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 30 (1965), S. 1815-1819 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 108 (1998), S. 3028-3037 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We develop an improved mean-field theory which allows us to describe the diffusive dynamics near phase transformations in condensed systems. Starting from a master equation for a stochastic lattice gas we obtain evolution equations on the single-particle level, whose stationary solutions in principle are consistent with the exact equilibrium statistics. Our method, which generalizes an approach proposed earlier, is based on a combination of a local equilibrium assumption and the lattice version of classical density functional theory. In the continuum limit, which is worked out for attractive interactions, generalized Cahn–Hilliard-type equations are recovered. Microscopic kinetic coefficients can be identified, which in general depend on the instantaneous local correlations in the nonequilibrium state. Moreover we study semi-infinite systems interacting with a planar wall and derive the appropriate boundary conditions to be imposed on the continuum equations. Applications to problems of the kinetics of phase changes influenced by a near wall are pointed out. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
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    Unknown
    Berlin : Periodicals Archive Online (PAO)
    Kant-Studien. 76:2 (1985) 214 
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  • 7
    facet.materialart.
    Unknown
    Berlin : Periodicals Archive Online (PAO)
    Kant-Studien. 76:1 (1985) 79 
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  • 8
    ISSN: 1432-2307
    Keywords: Human immunodeficiency virus ; Liver ; Hepatitis C ; Haemophilia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate the influence of human immunodeficiency virus (HIV) coinfection on preexisting long-term chronic C hepatitis (HCV) 68 liver biopsies from 22 HIV/HCV-coinfected, 13 HIV and 33 HCV-monoinfected patients and 71 livers obtained at autopsy from 26 HIV/HCV-coinfected and 45 HIV-monoinfected patients were studied by histo- and immunohistochemistry. All HIV patients had reached the advanced stage of immunodeficiency (stage III CDC), except for 3 haemophiliacs (stage II CDC). HCV infection was associated with a higher degree of portal, periportal and lobular inflammation — regardless of whether there was concurrent HIV infection. HIV/HCV coinfection was associated with a significantly higher rate of granulocytic cholangiolitis than HCV and HIV monoinfection (P 〈 0.05), a histological feature uncommon in C hepatitis. In HIV/HCV coinfection cholestasis was a predominant histological feature. HCV monoinfection and HCV/HIV coinfection were associated with the highest fibrosis index. In HIV/HCV coinfection centrilobular fibrosis was significantly more marked than in HCV monoinfection (P 〈 0.05), suggesting an HIV associated fibrogenic effect. Patients with chronic C hepatitis showed a significantly increased rate of posthepatitic cirrhosis compared with the patients without HCV infection (P 〈 0.05). At autopsy, 10 of the 20 HIV/HCV-coinfected haemophiliacs had developed cirrhosis because of chronic C hepatitis, whereas cirrhosis was found in only 2 of 6 HIV/HCV-coinfected non-haemophiliacs (1 case of chronic B and C hepatitis, and 1 case of chronic alcohol abuse). No cirrhosis was observed in the 45 autopsy patients with HIV monoinfection. The findings suggest that HIV coinfection aggravates the course of preceding long-term chronic C hepatitis by a more marked (centrilobular) fibrosis. HIV/HCV-coinfected patients are threatened by a higher rate of posthepatitic cirrhosis —particularly in multitransfused haemophiliacs — and cholestatic hepatopathy.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Virchows Archiv 412 (1988), S. 247-253 
    ISSN: 1432-2307
    Keywords: Pancreatic osteoclast-type giant cell tumour ; Differentiation ; Histogenesis ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two cases of osteoclast-type giant cell tumour of the pancreas (OGTP) are presented and compared with similar tumours of other locations and pancreatic carcinomas. One of the tumours was analyzed by immunohistochemical methods. The mononuclear stromal cells and osteoclast-like giant cells, which characterize this very rare neoplasm, reacted with an antibody against vimentin, but were not decorated by antibodies against lysozyme, alpha-1-ACHT, alpha-1-AT. Pleomorphic mononuclear cells in osteoid additionally contained osteonectin and could thus be identified as osteoblasts. Only the tumour glands stained positively with panepithelial keratin antibodies and antibodies against the keratin polypeptides 7, 18, 19. These results demonstrate for the first time the mesenchymal differentiation of the OGTP, which in some cases is also able to form epithelial structures. The immunohistochemical reactions and the characteristic morphology of the tumour show the OGTP to be an entity which must be differentiated from pancreatic carcinoma, especially from its giant cellular subtype.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Der Internist 38 (1997), S. 928-936 
    ISSN: 1432-1289
    Keywords: Schlüsselwörter Leberzirrhose ; Präkanzerose ; Virushepatitis ; Präkanzerose ; Hämochromatose ; Leberzirrhose ; Alpha1-Antitrypsinmangel ; Leberzirrhose ; Präkanzerose ; Primär sklerosierende Cholangitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zum Thema Leberzirrhosen unterschiedlichster Genese prädisponieren zur Bildung maligner Tumoren der Leber und der Gallengänge. Die Entstehung und Einwirkung von reaktiven Sauerstoffmediaten scheint ein gemeinsamer Pathomechanismus zu sein, der zu Schäden an DNA, Lipiden und Proteinen der Leber- und Gallezellen führt. Darüber hinaus spielen spezifische molekulare Mechanismen für die maligne Entartung bei alkoholinduzierter, posthepatitischer oder stoffwechselbedingter Leberzirrhose sowie primär sklerosierender Cholangitis eine Rolle.
    Type of Medium: Electronic Resource
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