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  • 1
    Electronic Resource
    Electronic Resource
    In vitro inhibition of cyclic AMP phosphodiesterase by cortisol (1976)
    [s.l.] : Nature Publishing Group
    Nature 262 (1976), S. 593-594 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In the course of experiments designed to elucidate the possible function of the adrenal glucocorticoids as stimulators of the cyclic AMP-mediated human chorionic gonadotropin (hCG) sensitivity of the postnatal Leydig cell in the rat5, we have tested the influence of cortisol on cyclic AMP ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/262593a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    A review of ENSO prediction studies (1994)
    Springer
    Climate dynamics 9 (1994), S. 167-179 
    Details
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract A hierarchy of ENSO (El Niño/Southern Oscillation) prediction schemes has been developed which includes statistical schemes and physical models. The statistical models are, in general, based on advanced statistical techniques and can be classified into models which use either low-frequency variations in the atmosphere (sea level pressure or surface wind) or upper ocean heat content as predictors. The physical models consist of coupled ocean-atmosphere models of varying degrees of complexity, ranging from simplified coupled models of the ‘shallow water’-type to coupled general circulation models. All models, statistical and physical, perform considerably better than the persistence forecast on predicting typical indices of ENSO on lead times of 6 to 12 months. The most successful prediction schemes, the fully physical coupled ocean-atmosphere models, show significant prediction abilities at lead times exceeding one year period. We therefore conclude that ENSO is predictable at least one year in advance. However, all of this applies to gross indices of ENSO such as the Southern Oscillation Index. Despite the demonstrated predictability, little is known about the predictability of specific features known to be associated with ENSO (e.g. Indian Monsoon rainfall, Southern African drought, or even off-equatorial sea surface temperature). Nor has the relative importance for prediction of different regional anomalies or different physical processes yet been established. A seasonal dependence in predictability is well established, but the processes responsible for it are not fully understood.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00208250
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Die Steigerung der Strahlenresistenz von Mäusen nach der intracerebralen Injektion von 5-Hydroxytryptamin (1972)
    Springer
    Radiation and environmental biophysics 8 (1972), S. 342-351 
    Details
    ISSN: 1432-2099
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Description / Table of Contents: Zusammenfassung 1. Nach einer intracerebralen Injektion von 5-Hydroxytryptamin ist die Mortalität von Mäusen, die nach einer Ganzkörperbestrahlung auftritt, herabgesetzt. Die Zeitabhängigkeit dieses Schutzeffektes und der Dosisreduktionsfaktor derZL 50/30 sind identisch mit den Beobachtungen, die nach intraperitonealer Applikation des Amins gemacht werden. 2. Das intracerebral injizierte 5-Hydroxytryptamin wird im Hirn sehr schnell abgebaut und die Metabolite verlassen das ZNS. In den peripheren Organen werden nur Metabolite des Amins beobachtet. 3. Auf Grund dieser Untersuchungen und histo-autoradiographischer Ergebnisse muß angenommen werden, daß die Schutzwirkung des Amins im ZNS, möglicherweise in Bereichen des Hypothalamus, induziert wird. Zentralnervöse Regulationsvorgänge führen zu Veränderungen in den peripheren Organen, die eine Resistenzsteigerung bedingen. Die Art dieser Veränderungen ist bisher ungeklärt. Die durch 5-Hydroxytryptamin bedingte Hypothermie kommt dabei nicht in Betracht. Die Wirkung über eine Hypoxie kann nicht völlig ausgeschlossen werden.
    Notes: Summary 1. The survival rate of mice was studied after whole-body X-irradiation and intracerebral injection of 5-hydroxytryptamine. An increase of the survival rate was observed when the intracerebral injection was performed before irradiation. The dependance of the protective effect on the period between injection and irradiation as well as the dose reduction factor of theDL 50/30 are identical with observations made after the intraperitoneal administration of 5-hydroxytryptamine. 2. The intracerebrally injected amine is rapidly metabolized in the brain and the metabolites leave the CNS. In the peripheral organs only metabolites of 5-hydroxytryptamine have been observed. 3. From these investigations and histo-autoradiographic results it is assumed that the radioprotective effect of the amine is induced in the CNS, possibly in hypothalamic regions. Central nervous regulatory processes bring about changes in the peripheral organs which lead to the increased radioresistance of the organism. The characteristics of these changes are unknown. Hypothermia induced by 5-hydroxytryptamine can be ruled out in this connection. The participation of hypoxic effects cannot completely be excluded.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01190620
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    A review of ENSO prediction studies (1994)
    Springer
    Climate dynamics 9 (1994), S. 167-179 
    Details
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract. A hierarchy of ENSO (El Niño/Southern Oscillation) prediction schemes has been developed which includes statistical schemes and physical models. The statistical models are, in general, based on advanced statistical techniques and can be classified into models which use either low-frequency variations in the atmosphere (sea level pressure or surface wind) or upper ocean heat content as predictors. The physical models consist of coupled ocean-atmosphere models of varying degrees of complexity, ranging from simplified coupled models of the ‘shallow water’-type to coupled general circulation models. All models, statistical and physical, perform considerably better than the persistence forecast on predicting typical indices of ENSO on lead times of 6 to 12 months. The most successful prediction schemes, the fully physical coupled ocean-atmosphere models, show significant prediction abilities at lead times exceeding one year period. We therefore conclude that ENSO is predictable at least one year in advance. However, all of this applies to gross indices of ENSO such as the Southern Oscillation Index. Despite the demonstrated predictability, little is known about the predictability of specific features known to be associated with ENSO (e.g. Indian Monsoon rainfall, Southern African drought, or even off-equatorial sea surface temperature). Nor has the relative importance for prediction of different regional anomalies or different physical processes yet been established. A seasonal dependence in predictability is well established, but the processes responsible for it are not fully understood.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003820050017
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    63. Spätrekonstruktion der weiblichen Brust nach Thoraxverbrennung im Kindesalter (1986)
    Springer
    Langenbeck's archives of surgery 369 (1986), S. 309-309 
    Details
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01274380
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    Paper (German National Licenses)
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