ISSN:
0951-4198
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Physics
Notes:
Electrospray ionization and fast-atom bombardment (FAB) are both soft ionization techniques which typically give prominent molecular ions of thermally labile and highly polar molecules. These two complementary techniques were compared on the same magnetic sector mass spectrometer, a Finnigan MAT 900. Comparisons were made of sensitivity, versatility, ease of use, and most importantly for our work, structure elucidation of unknowns arising from research with agricultural chemicals. Both known standards and ‘real world’ unknowns were analyzed by liquid chromatography/mass spectrometry (LC/MS) with both interfaces. The same reversed-phase micro-LC system was used with both ionization techniques, using 0.32 mm i.d. packed capillary LC columns at flow rates of 1-2 μL/min. Improved performance in the continuous-flow FAB mode was obtained by use of a screen target. The advantages, disadvantages and similarities of these two ionization techniques are discussed.
Additional Material:
7 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/rcm.1290080306
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