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  • 1
    Electronic Resource
    Electronic Resource
    Development of standard direct coal liquefaction activity tests for fine-particle size, iron-based catalysts (1994)
    s.l. : American Chemical Society
    Energy & fuels 8 (1994), S. 117-123 
    Details
    ISSN: 1520-5029
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Energy, Environment Protection, Nuclear Power Engineering , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ef00043a020
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  • 2
    Electronic Resource
    Electronic Resource
    Patch-clamp profile of ion channels in resting murine B lymphocytes (1990)
    Springer
    The journal of membrane biology 114 (1990), S. 175-188 
    Details
    ISSN: 1432-1424
    Keywords: anion channel ; potassium channel ; chloride channel ; patch clamp ; single-channel recording ; murine B lymphocytes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Patch-clamp studies of single ion channel currents in freshly isolated murine B lymphocytes are characterized here according to their respective unitary conductances, ion selectivities, regulatory factors, distributions and kinetic behavior. The most prevalent ion channel in murine B lymphocytes is a large conductance (348 pS) nonselective anion channel. This report characterizes additional conductances including: two chloride channels (40 and 128 pS), a calcium-activated potassium channel (93 pS), and an outwardly rectifying potassium channel which displays two distinct conductances (18 and 30 pS). Like the anion channel, both chloride channels exhibit little activity in the cellattached patch configuration. The kinetic behavior of all of these channels is complex, with variable periods of bursting and flickering activity interspersed between prolonged closed/open intervals (dwell times). It is likely that some of these channels play an important role in the signal transduction of B cell activation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01869098
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  • 3
    Electronic Resource
    Electronic Resource
    Ion channels in human macrophages compared with the U-937 cell line (1987)
    Springer
    The journal of membrane biology 96 (1987), S. 57-64 
    Details
    ISSN: 1432-1424
    Keywords: ion channels ; human macrophages ; U-937 cell line
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary The human cell line U-937 has been used extensively to model many macrophage functions. We have examined the cell membranes of human monocyte-derived macrophages (HMDM) and U-937 cells to compare membrane properties as expressed by single ion channel currents. The patch-clamp technique was applied to isolated, nonactivated, inside-out patches of cell membranes obtained from HMDM and from the U-937 cell line. Voltage-gated potassium channels of similar conductance but different kinetics are present in both types of cells, and a calcium-activated potassium channel is present only in the HMDM. These differences in ion channel properties suggest fundamentally different behavior between these two cell types at the level of the cell membrane.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01869334
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  • 4
    Electronic Resource
    Electronic Resource
    UNIQUE PROPERTIES OF THE MOTH MYOCARDIUM (1965)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 127 (1965), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1965.tb49393.x
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  • 5
    Electronic Resource
    Electronic Resource
    Identification of two critical base pairings in 5' untranslated regions affecting translation efficiency of synthetic uncapped globin mRNAs
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Gene Structure and Expression 1130 (1992), S. 29-37 
    Details
    ISSN: 0167-4781
    Keywords: Base pair ; Globin ; Translation efficiency ; Untranslated region ; mRNA
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0167-4781(92)90457-B
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  • 6
    Electronic Resource
    Electronic Resource
    The Risk of High Multiparity with IVF/ET (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Birth 15 (1988), S. 0 
    Details
    ISSN: 1523-536X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: : From 1980 to 1985 not only were more infants delivered at higher-order multiple births, but more survived. The rise in multiple gestation has been attributed in part to the drugs and procedures used in the management of infertility and assisted conception, especially multiple embryo transfer after in vitro fertilization and multiple egg transfer in the gamete intrafallopian transfer procedure. Very often, survival of small infants from higher-order multiple gestations taxes the resources of the medical and social services. If they survive the perinatal period, the feeding, nurturing, and physical care of triplets, quadruplets, quintuplets, or sextuplets places extraordinary demands on their caretakers. The problems and risks extend far beyond individual clinical cases to the wider social ramifications of the birth and care of these children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1523-536X.1988.tb01097.x
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  • 7
    Electronic Resource
    Electronic Resource
    Developmental Pattern for Phosphatidylserine Decarboxylase in Rat Brain (1986)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 46 (1986), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: In adult rats, a significant portion of brain ethanolamine glycerophospholipids are synthesized by a pathway involving phosphatidylserine decarboxylase, a mitochondrial enzyme. We have now examined whether this enzyme plays a particularly prominent role during development. Activities for both phosphatidylserine decarboxylase and succinate dehydrogenase (another mitochondrial enzyme) were determined in brain homogenates from rats 5 days of age to adulthood. Succinate dehydrogenase activity, expressed on a per unit brain protein basis, increased markedly during development. This pattern has been reported previously and is as expected from the postnatal increase in oxidative metabolism. In contrast, phosphatidylserine decarboxylase activity decreased 40% from 5 to 30 days of age. The apparent Km for brain phosphatidylserine decarboxylase was 85 μM in both young (8- and 20-day-old) and adult animals. Parallel studies in vivo were carried out to determine the contribution of the phosphatidylserine decarboxylase pathway, relative to pathways utilizing ethanolamine directly, to the synthesis of brain ethanolamine glycerophospholipids. Animals were injected intracranially with a mixture of L-[G-3H]serine and [2-14C]ethanolamine and incorporation into the base moieties of the phospholipids determined. The 3H/14C ratio of ethanolamine glycerophospholipids decreased about 50% during development. Our studies in vitro and in vivo both suggest that phosphatidylserine decarboxylase plays a significant role in the synthesis of brain ethanolamine glycerophospholipids at all ages, although it is relatively more prominent early in development.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1986.tb00638.x
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  • 8
    Electronic Resource
    Electronic Resource
    Lipid Metabolism During Early Stages of Wallerian Degeneration in the Rat Sciatic Nerve (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 52 (1989), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract We examined changes in biosynthetic capacity of sciatic nerve during the early stages of Wallerian degeneration, utilizing a model that permits exclusion of nonresident cells from degenerating nerve. Sciatic nerve segments were placed in either 5-μm pore (allowing infiltration of nonresident cells) or 0.22-μm pore (excluding nonresident cells) Millipore diffusion chambers and then implanted in the peritoneal cavity of the same 32-34-day-old rat. At times up to 7 days post-surgery, nerve segments from the chambers, as well as control segments from the contralateral sciatic nerve, were removed and their capacity to incorporate radioactive precursors into lipids and proteins assayed in vitro. In nerve segments from both the 0.22- and 5-μm pore chambers, incorporation of [14C]acetate into total lipids was decreased relative to control by 50% at 12 h postsurgery and by 85% at day 3. This decreased incorporation of [14C]acetate reflects primarily decreased de novo synthesis of cholesterol and of fatty acyl residues incorporated into glycerolipids and sphingolipids. There was a preferentially decreased synthesis of cerebrosides and cholesterol (components enriched in myelin) relative to other lipids, while cholesterol esters and free fatty acids (products of membrane degradation) accounted for a greater proportion of the greatly reduced levels of total lipid label. In contrast to [14C]acetate, incorporation of [3H]glycerol into lipids was increased up to fourfold, relative to control, 1 day after nerve transection. This increased incorporation of [3H]glycerol does not reflect de novo synthesis of lipids (which is decreased), but rather removal of toxic fatty acyl residues derived from degradation of myelin lipids; these toxic compounds must be removed by resynthesis into nonmyelin glycerolipids and cholesterol esters. The inhibition of de novo synthesis of myelin lipids in Schwann cells during the early stages of Wallerian degeneration occurs independently of hematogenously-derived cells. We suggest that Wallerian degeneration rapidly results in some breakdown of myelin, and that the increased free fatty acid levels resulting from degradation of myelin lipids inhibit the de novo synthesis of new myelin lipid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-4159.1989.tb01851.x
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  • 9
    Electronic Resource
    Electronic Resource
    Studies of catalyst samples from a two-stage direct coal liquefaction run (1987)
    s.l. : American Chemical Society
    Industrial & engineering chemistry research 26 (1987), S. 840-846 
    Details
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ie00064a037
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  • 10
    Electronic Resource
    Electronic Resource
    Hydrous metal oxide ion exchangers for preparation of catalysts for direct coal liquefaction (1985)
    s.l. : American Chemical Society
    Industrial and engineering chemistry 24 (1985), S. 15-19 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/i300017a004
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