Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Dynamic changes in acid mucopolysaccharides during mineralization of the mandibular condylar cartilage (1973)
    Springer
    Histochemistry and cell biology 36 (1973), S. 185-192 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Sequential histochemical changes related to acid mucopolysaccharides (AMPS) were studied in the calcifying cartilage of the mandibular condyle. Non-decalcified, 1 μ Eponembedded sections were subjected to a variety of histochemical procedures. The results indicate that AMPS are synthesized and secreted mainly by hypertrophic chondrocytes in the premineralizing zone. Within the matrix at the mineralization front the AMPS complexes are apparently degraded by lysosomal enzymes to yield a highly anionic fraction which is maintained in the matrix. This fraction could function as the site for mineralization and cationic dye reaction which allows for histochemical visualization.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00304393
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Ultrastructural localization of acid phosphatase in cartilage of young mandibular condyles (1973)
    Springer
    Histochemistry and cell biology 37 (1973), S. 365-369 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The fine structural localization of acid phosphatase was studied in cartilage of mandibular condyles of the mouse. Although the final product was found to be deposited within most chondroblasts and chondrocytes, the most abundant precipitate was observed within the hypertrophic chondrocytes in the vicinity of the mineralization front. In these cells, lead phosphate precipitates were noted along the rough endoplasmic reticulum and within lysosome-like bodies. Positive reaction to acid phosphatase was also noticed within vacuoles which were located in the matrix close to the centers of mineralization. It is conceivable that this enzyme is involved in matrix production at one stage of chondrogenesis and in the mineralization process at a later stage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00274971
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Demonstration and distribution of acidic glycosaminoglycans in mouse secondary cartilage. Light and electron microscopic study (1974)
    Springer
    Histochemistry and cell biology 38 (1974), S. 85-93 
    Details
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The distribution of acidic glycosaminoglycans (AGAG) was studied in the calcifying cartilage of the developing mandibular condyle of the mouse. Non-fixed frozen sections were subjected to light microscopy examination, while fixed specimens were prepared for electron microscopy studies through the use of ruthenium red. The results indicate that the AGAG complexes appear in two forms within the matrix at the premineralizing hypertrophic zone. In the latter zone these anionic macromolecules appear in close association with lysosome-like bodies. In the mineralizing zone, AGAG ascertain a more homogeneous configuration, usually in the form of small, dark granules. At this zone the ruthenium red reactive granules oftenly line up along collagen fibrils. Although it is still impossible to infer the meaning of these findings to the overall metabolism of AGAG in mineralizing cartilage, it is conceivable that these macromolecules represent structural as well as metabolic heterogeneity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00490222
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Prenatal development of the mandibular joint in miceSupported by grant DE 01578-02 from the National Institute of Dental Research, United States Public Helath Service. (1964)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 150 (1964), S. 449-461 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The prenatal development of the mandibular joint in mice was studied in fetuses at 15 to 20 days insemination age. The ramus of the mandible can be delineated as early as the fifteenth day by distinct differences in the degree of condensation of mesenchyme at the site of the future joint. The future condylar process of the mandible can be recognized in its relationship to the external pterygoid muscle, inferior alveolar nerve, Meckel's cartilage, pre-cartilaginous alisphenoid process of the future basisphenoid bone, and the anlage of the squamosal bone with its zygomatic process.Differentiation is rapid through the twentieth day of gestation at which time the following major elements of the joint can be recognized: a fibrous intra-articular disc continuous with the tendon of the external pterygoid muscle; a vascular synovial mesenchyme with upper and lower synovial spaces; an ossified squamosal bone with a fibrous joint lining; and a well developed condylar process with good representation of differentiating cells in the zones of chondrification and ossification.Among the elements not yet evident, however, are (1) hemopoietic marrow in the condyle, (2) a constricted neck at the base of the condyle, and (3) a fibrous capsule or capsular ligament.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091500414
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Development and distribution of elastic fibers in the mandibular joint of the mouse. A comparison of fetal, suckling, juvenile and adult stagesSupported by grant DE 01578-03 from the National Institute of Dental Research, United States Public Health Service. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 156 (1966), S. 333-345 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Development and distribution of elastic fibers were studied in mandibular joints of white Swiss mice which ranged from 15 days insemination age to three months postnatal. Paraffin sections were stained with Weigert's resorcin-fuchsin and Verhoeff's elastic tissue stain.Elastogenesis does not begin until the major elements of the mandibular joint are present. The first distinct elastic elements appear as granules at the nineteenth to twentieth day insemination age. Early sites of elastogenesis occur in the peripheral portions of the articular disk, at the transition and continuation of fibrous disk tissue with the periarticular tissues, and with the periosteum around the neck of the mandible.The concentration, length and caliber of fibers is increased markedly during the suckling stage, especially in the walls of the medial and lateral recesses of the synovial cavities, and in the posterior continuation of the disk to form a fibroelastic band of attachment to the squamosal bone. Prominent bands of long elastic fibers appear in the epimysium of the lateral pterygoid and masseter muscles in the young adult.The central portion of the disk and the articular surfaces of the mandibular condyle and fossa contain no elastic fibers, confirming the contention that these surfaces are not particularly stress-bearing. Stretch and shearing stresses are created, however, which require extensive elastic fiber development in other joint tissues.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091560308
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    The nature of endochondral ossification in the mandibular condyle of the mouse (1972)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 172 (1972), S. 659-667 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Through the application of histological and histochemical techniques, this study demonstrates that the ossification process of the mandibular condyle differs basically from that of other endochondral growth sites. In the epiphyseal plate of a typical long bone, the cartilage cells are known to undergo degenerative processes and death. In the mandibular condyle, however, the cartilage cells keep their vitality throughout the cartilage zones. In the lower border of the calcified cartilage, adjacent hypertrophic cartilage cells fuse after the dissolution of the intervening matrix to form multinuclear chondroclasts. These giant cells reveal marked positive reaction to mitochondrial and lysosomal enzymes. It is suggested that these enzymes are active in the resorption process of the calcified cartilage matrix, which is an integral phase of the ossification mechanism of the condylar growth center. It is believed that the mandibular condyle of the mouse demonstrates a specific type of endochondral ossification, in which the hypertrophic chondrocytes are not dying cells, but contribute actively to the process of bone formation.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091720406
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Further evidence for the vitality of chondrocytes in the mandibular condyle as revealed by 35S-sulfate autoradiographySupported in part by grant DE 00163 from the National Institute of Dental Research, U.S.P.H.S. (1972)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 174 (1972), S. 503-511 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Histochemical and autoradiographic studies using 35S-sulfate indicate that the majority of the cartilage cells in the developing mandibular condyle of the young mouse are active, vital cells. Concomitant with the increase of hypoxic conditions within the deeper layers of the cartilage, an increase in sulfated glycosaminoglucuronoglycans synthesis takes place. Hypertrophic chon-drocytes in the premineralized and mineralized zones reveal marked 35S-sulfate uptake in comparison with the less differentiated cells in the chondroblastic and perichondrial zones. These observations of radiosulfate activity support the concept that calcification processes in the condylar cartilage are not necessarily accompanied by degeneration and death of the hypertrophic chondrocytes. The radiosulfate activity of the surviving chondrocytes in the vicinity of the ossification front indicates possible modulation into osteoprogenitor cells.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091740409
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Quantitative morphology and carbohydrate histochemistry of the mouse submandibular gland following prepubertal castration (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 144 (1975), S. 137-147 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The endocrinologic basis for morphological and biochemical sex differences in the mouse submandibular gland have not been clarified. Previous studies have emphasized the maintenance of glandular differences in adult animals, rather than considering the factors responsible for their developmental etiology. Male CD-1 mice were castrated at intervals between 10 and 50 days of age and killed at 100 days. The quantitative development of granular tubules and the carbohydrate histochemistry of the submandibular glands were compared to untreated males and females. The area of granular tubules increased with age at castration. Nested analysis of variance indicated significant differences among treatments and among sections within individual glands. No group of castrated males had a greater development of tubules than untreated females. Carbohydrate histochemistry demonstrated an increase in carboxylated mucosubstances in the acinar cells and granular tubule cells of castrated animals.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001440203
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Vitality of chondrocytes in the mandibular condyle as revealed by collagen formation. An autoradiographic study with 3H-prolineSupported in part by grant DE 00163 from the National Institute of Dental Research, U.S.P.H.S. (1972)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 135 (1972), S. 359-369 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Histological and autoradiographic studies using 3H-proline indicate that cartilaginous tissue in the mandibular condyle maintains morphologic and metabolic characteristics of an embryonic type of tissue. Cartilage cells in the condyle lack the specific arrangement and cellular homogeneity characteristic of more differentiated endochondral growth sites. Through dedifferentiation many chondrocytes in the mandibular condyle appear to outlive the hypoxic conditions that are reported to prevail within the mineralizing zone. Chondrocytes in this zone reveal only a minimal amount of 3H-proline uptake in comparison with the cells in the chondroblastic and premineralizing zones. The dedifferentiated chondrocytes appear to redifferentiate into more specialized cells, possibly osteoprogenitor cells, as they reveal a significant increase in 3H-proline incorporation in the vicinity of the ossifying front. These observations on proline metabolism support the concept that calcification in the condylar cartilage is not necessarily accompanied by degeneration and death of the chondrocytes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001350305
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Hydrolytic enzyme activity during endochondral ossification of secondary cartilageSupported in part by Tufts University Institutional Cancer grant IN-23-0, and by the Medical Foundation, Incorporated, Boston, Massachusetts. (1974)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 140 (1974), S. 369-381 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Reactions for hydrolytic enzymes such as aminopeptidase, β-glucuronidase, N-acetyl-β-glucosaminidase, arylsulfatase and non-specific esterases indicated various degrees of activity within the chondrocytes of the young mandibular condyle. Most of the reaction products of the above enzymes appeared as discrete granules, which might indicate a lysosomal origin. The most intense activity of these enzymes was observed within chondroblasts and premineralizing hypertrophic chondrocytes. However, chondrocytes within the mineralizing zone also appeared synthetically active. The latter cells, as well as those at the adjacent ossification front, revealed some activity by a majority of the enzymes tested. This could indicate that some metabolic functions, although reduced in degree, continue in the cells of these mineralizing zones of endochondral ossification.Matrical reactions, with the exception of arylsulfatase and aminopeptidase, were essentially negative. The positive reactions for the latter enzymes might be an indication of their involvement in the process of extracellular mineralization.
    Additional Material: 2 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001400305
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...