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  • 1
    Electronic Resource
    Electronic Resource
    Stem Cells from Primordial Germ Cells Can Reenter the Germ Line
    Amsterdam : Elsevier
    Developmental Biology 161 (1994), S. 626-628 
    Details
    ISSN: 0012-1606
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1006/dbio.1994.1058
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  • 2
    Electronic Resource
    Electronic Resource
    Constitutive heterochromatin variation in two species of rattus with apparently similar karyotypes (1977)
    Springer
    Genetica 47 (1977), S. 77-80 
    Details
    ISSN: 1573-6857
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Rattus blanfordi and R. cutchicus medius both have a chromosome complement of 2n=36 and all chromosomes except the submetacentric Y of R. blanfordi are acrocentric. The apparently similar karyotypes of the two species, however, show variations in the nature and quantity of C-band-positive constitutive heterochromatin (C-heterochromatin) as revealed by C- and G-banding and Hoechst 33258 fluorescence. R. blanfordi with large-sized X and Y chromosomes and conspicuously larger centromeric heterochromatin in all the autosomes as compared to that of R. cutchicus medius has much more C-heterochromatin in its genome than the latter. The variation in the quantity of C-heterochromatin has been accomplished without altering the morphology of the acrocentric chromosomes unlike other mammals in which variations have been reported to result generally in the addition or deletion of a totally heterochromatic second arm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00122444
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  • 3
    Electronic Resource
    Electronic Resource
    Similarity in the G-band patterns of constitutive heterochromatin of the composite X and Y chromosomes of certain rodents (1981)
    Springer
    Genetica 54 (1981), S. 281-284 
    Details
    ISSN: 1573-6857
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00135047
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  • 4
    Electronic Resource
    Electronic Resource
    Cytogenetic relationships inRattus, Cremnomys, Millardia, Nesokia andBandicota (Rodentia: Muridae) (1983)
    Springer
    Genetica 61 (1983), S. 21-40 
    Details
    ISSN: 1573-6857
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The karyology was studied in different taxa ofRattus, Cremnomys, Millardia, Nesokia andBandicota. Chromosome banding patterns of 18 taxa belonging to 4 species of the genusRattus, 2 species ofCremnomys, 1 species each ofMillardia andNesokia and 2 species ofBandicota are presented. Present studies and the karyological information of different taxa available from elsewhere have revealed that the karyotypes ofMillardia, Cremnomys, Lenothrix (exceptL. canus) andMaxomys (M. bartelsii only) are unique and show little resemblance toRattus, Stenomys, Berylmys andLeopoldamys. G-band comparison has revealed the presence of 4 pairs of similar autosomes in addition to conservation of the G-band pattern of the X chromosome in divergent karyotypes ofRattus rattus, Millardia meltada andCremnomys cutchieus medius. Chromosome inversions, fusions and variations in constitutive heterochromatin have been identified. The presence of a few similar chromosomes suggests that these taxa have evolved from a common ancestral taxon. The conventional karyotype ofLenothrix canus and theNiviventer group of rats (Marshall, 1977) also reveal a pair of large subtelocentrics and a few pairs of small metacentrics similar to those observed in the subgeneraRattus, Stenomys, Berylmys andLeopoldamys. The autosomal complements of the lesser bandicoot-ratsNesokia indica andBandicota bengalensis are alike and are related to those of species in the subgenusRattus through only 2 pericentric inversions. A few pericentric inversions and a deletion may be assumed to compare the karyotype of the great bandicoot-ratB. indica indica withB. bengalensis. The other great bandicoot-rats,B. indica nemorivaga andB. indica savilei, have an additional pair of autosomes and the karyotype of the former subspecies has diversified through a few pericentric inversions also.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00563229
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  • 5
    Electronic Resource
    Electronic Resource
    Supernumerary chromosomes in Bandicota indica nemorivaga and a female individual with XX/XO mosaicism (1982)
    Springer
    Genetica 58 (1982), S. 103-108 
    Details
    ISSN: 1573-6857
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Supernumerary chromosomes and an XX/XO mosaic individual of B. i. nemorivaga are described. The supernumeraries are small metacentric chromosomes and are stained all along their length in C-band preparations. They have morphology and staining characteristics similar to those observed in different populations of Rattus rattus. Extensive G-band similarity of the chromosomes of B. i. nemorivaga and R. rattus and the size, shape and staining behaviour of the supernumerary chromosomes in these genera suggest that they have acquired supernumeraries from a common ancestor.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00056777
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  • 6
    Electronic Resource
    Electronic Resource
    Distribution of silver-stained nucleolus-organizing regions in the chromosomes of the Equidae (1983)
    Springer
    Genetica 62 (1983), S. 109-116 
    Details
    ISSN: 1573-6857
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The distribution of silver-stained nucleolus-organizing regions (NORs) in fibroblast chromosomes from all seven extant species of Equidae are described. There are variations in the number and locations of silver-stained NORs in different species but most of the cells in an individual of any speies had only 2 to 4 silver-stained NORs. In Equus przewalskii and E. caballus NORs were detected on up to three different chromosomes. In E. asinus 11 different chromosomes were observed to possess NOR sites. E. hemionus kulan and E. hemionus onager had NORs on 2 large metacentric pairs and a small acrocentric pair. In E. grevyi and E. burchelli NORs were located on 3 to 4 different pairs. E. zebra hartmannae had silver-staining over the telomere regions of the short arms of the chromosomes 1, 3 and 4. A comparison of G-banded chromosomes and silver-stained NORs has revealed one autosome with conserved G-band patterns and possessing a silver-staining NOR in all the species except E. asinus. Variations in the number and multichromosomal locations of NORs in various species could have evolved by pairing and exchanges between non-homologous chromosomal heterochromatin having similar satellite DNA sequences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00116632
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  • 7
    Electronic Resource
    Electronic Resource
    Genetic analysis of tumerigenesis: XVI. Chromosome changes in azacytidine- and insulin-induced tumorigenesis (1984)
    Springer
    Somatic cell and molecular genetics 10 (1984), S. 521-529 
    Details
    ISSN: 1572-9931
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Chromosome changes accompanying differentiation and tumorigenesis in azacytidine- (azaC) and insulin-induced preadipocytes of the Chinese hamster embryo fibroblast cell line CHEF/18 are described. Karyotype analysis of 47 clones, subclones, and tumor-derived cells has shown that trisomy for chromosome 3q (mar 1) is characteristic of azaC preadipocytes but not of insulin preadipocytes. AzaC preadipocytes were consistently tumorigenic as well as trisomic for chromosome 3q, whereas most insulin preadipocytes were nontumorigenic and diploid. Only the few insulin preadipocytes that were tumorigenic were also trisomic for chromosome 3q. Among the tumor-derived cell lines recovered from azaC preadipocytes injected into nude mice, four had no additional chromosome changes except trisomy for 3q, as detected by karyotype analysis. Thus trisomy for 3q may be a sufficient chromosome change to induce tumor-forming ability in these cells. The rearrangements of chromosome 3 seen in this and other work pinpoint the trisomic region between the centromere and 3q5.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01534856
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  • 8
    Electronic Resource
    Electronic Resource
    Genetic analysis of tumorigenesis: X. Chromosome studies of transformed mutants and tumor-derived CHEF/18 cells (1982)
    Springer
    Somatic cell and molecular genetics 8 (1982), S. 677-689 
    Details
    ISSN: 1572-9931
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Chinese hamster embryo fibroblast cell line CHEF/18 is stably diploid, anchorage-dependent, has a high serum requirement, and does not form tumors in nude mice. The chromosome constitutions of spontaneous and chemically induced anchorage-independent and/or low-serum CHEF/18 mutants and tumors produced in nude mice by some of these mutants are compared. We find a correlation between diploidy and nontumorigenicity among the anchorage-independent mutants but not in the low-serum mutants. One of the four spontaneous and six of the 15 chemically induced anchorage mutants have remained diploid. The remaining 12 mutants are pseudodiploid or aneuploid, and seven of them contain changes in chromosome 1, either a translocation or a deletion involving breakage at the same position (1q11–12). Each of the tumors induced by six mutants has a unique pattern of rearrangements;however five of the six have changes involving chromosome 3. This chromosome was also frequently rearranged in tumorderived cells previously investigated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01542860
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