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  • 1
    Electronic Resource
    Electronic Resource
    Phage-displayed Bet mim 1, a mimotope of the major birch pollen allergen Bet v 1, induces B cell responses to the natural antigen using bystander T cell help (2002)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 32 (2002), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background and objective In previous studies we have generated mimotopes of Bet v 1, the major birch pollen allergen, by biopannings of phage-display random peptide libraries. In the present study, we analysed the humoral and cellular immune response to Bet v 1-mimotopes.Methods The mimotope CFPYCYPSESA, designated Bet mim 1, was used for intraperitoneal immunizations of BALB/c mice in phage-displayed form. For examination of the humoral immune response, enzyme-linked immunosorbent assay (ELISA) experiments were applied. Stimulation capacities were investigated in cultured mouse splenocytes and in humoral Bet v 1-specific T cell clones.Results We demonstrated that the Bet mim 1-induced murine antibody response against Bet v 1 was predominated by the IgG1 isotype. In these mice only the phage-displayed mimotopes, but neither the allergen nor the synthetic Bet mim 1-mimotopes were able to stimulate proliferation of cultured splenocytes. Using Bet v 1-specific T cell clones of allergic patients, phage-displayed and synthetic mimotopes were unable to stimulate T cell proliferation. Moreover, tolerance induction to Bet v 1 in mice by intranasal administration of Bet mim 1-phages or Bet mim 1-peptide failed.Conclusion Taking these results together, our data indicate that Bet mim 1 mimics a Bet v 1-epitope on the B cell but not on the T cell level. We suggest that the phage itself is responsible for the recruitment of T cells providing bystander help in the formation of a mimotope-specific humoral response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2002.01527.x
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  • 2
    Electronic Resource
    Electronic Resource
    Cr2,4Pt1,7C, ein neues Perowskit-Carbid (1965)
    Springer
    Monatshefte für Chemie 96 (1965), S. 1781-1782 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01185899
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  • 3
    Electronic Resource
    Electronic Resource
    Neue Boride mit Cr23C6-Struktur (1965)
    Springer
    Monatshefte für Chemie 96 (1965), S. 1144-1146 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00904258
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  • 4
    Electronic Resource
    Electronic Resource
    NeueE-Phasen (1967)
    Springer
    Monatshefte für Chemie 98 (1967), S. 95-99 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Abstract The crystal structure of TaNiGe has been examined by means of a Fourier-Synthesis. TaNiGe was found to be isotypic with TiNiSi (ordered PbCl2-type) already described byClara B. andD. P. Shoemaker The lattice parameters of the followingE-phases have been determined: ZrPdSi, ZrPtSi. ZrPtGe, ZrCuSi, ZrCuGe, HfFeSi, HfCoSi, HfCoGe, HfNiSi, HfNiGe, HfCuSi, TaNiGe, NbNiSi, TaFeGe and TaCoGe.
    Notes: Zusammenfassung Die Kristallstruktur von TaNiGe wird mit Hilfe einer Fourier-synthese bestimmt und als geordneter PbCl2-Typ erkannt. Damit wird die Struktur der E-Phasen, welche vonClara B. undD. P. Shoemaker an TiNiSi bereits ermittelt wurde, bestätigt. Folgende neue E-Phasen werden aufgefunden, die Gitterparameter ermittelt: ZrPdSi, ZrPtSi, ZrPtGe, ZrCuSi, ZrCuGe, HfFeSi, HfCoSi, HfCoGe, HfNiSi, HfNiGe, HfCuSi, TaNiGe. Ferner werden die Gitterparameter der schon bekanntenE-Phasen NbNiSi, TaFeGe und TaCoGe bestimmt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00901102
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  • 5
    Electronic Resource
    Electronic Resource
    Ternäre Phasen mit MgZn2−Ty (1965)
    Springer
    Monatshefte für Chemie 96 (1965), S. 1658-1659 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00902104
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  • 6
    Electronic Resource
    Electronic Resource
    Die Kristallstruktur von Co4Hf2P3 (1968)
    Springer
    Monatshefte für Chemie 99 (1968), S. 566-574 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Abstract The structure of a ternary phase with the ideal composition Co4Hf2P3 has been determined and refined by means of singlecrystal X-ray methods. The cell dimensions of the hexagonal unit cell are found to be:a=12,0559 andc=3,6249 Å, the space group is $$D_{3h}^3 ---P\bar 62m$$ . The phase is structurally related to Fe2P and Fe12Zr2P7.
    Notes: Zusammenfassung Die Struktur einer ternären Phase mit der Idealzusammensetzung Co4Hf2P3 wurde röntgenographisch mittels Einkristallmethoden bestimmt und verfeinert. Die Gitterparameter der hexagonalen Elementarzelle sinda=12,0559 undc=3,6249 Å, die Raumgruppe ist $$D_{3h}^3 ---P\bar 62m$$ . Die Phase ist strukturell mit Fe2P und Fe12Zr2P7 verwandt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00901205
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  • 7
    Electronic Resource
    Electronic Resource
    Über einige Phasen mit Ti3P-Struktur (1966)
    Springer
    Monatshefte für Chemie 97 (1966), S. 1696-1697 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00901445
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  • 8
    Electronic Resource
    Electronic Resource
    Die Kristallstruktur des Ta6Cu8Be15 und verwandter Phasen (1965)
    Springer
    Monatshefte für Chemie 96 (1965), S. 1206-1208 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00904268
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  • 9
    Electronic Resource
    Electronic Resource
    Zum Problem der Carbohydride (1965)
    Springer
    Monatshefte für Chemie 96 (1965), S. 1563-1566 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Abstract Powder of Zr-carbohydride containing about 20 atomic % H, prepared out of ZrC∼0,6, has been examined by neutron diffraction a superstructure being observed according:a zrC 0,6H0,4=2a zrC 0,6. The structural type can be explained by partial ordered filling of the tetrahedral sites.
    Notes: Zusammenfassung Ein Zirkoniumcarbohydrid-Pulver, das aus ZrC∼0,6 hergestellt wird und etwa 20 At% H enthält, wird mittels Neutronenbeugung untersucht. Die dabei beobachtete Überstruktur — der Gitterparameter der kfl. Zelle des Carbohydrids ist gleich dem doppelten von ZrC0,6 bzw. der erneut dehydrierten Probe —läßt sich durch teilweise geordneten Einbau der H-Atome auf Tetraederpositionen deuten.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00902090
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  • 10
    Electronic Resource
    Electronic Resource
    Die Kristallstruktur von Nb5Cu4Si4 (1968)
    Springer
    Monatshefte für Chemie 99 (1968), S. 549-556 
    Details
    ISSN: 1434-4475
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Abstract The crystal structure of Nb5Cu4Si4 has been determined and refined by single-crystal X-ray methods. The cell dimensions of the tetragonal body-centered unit cell are found to be:a=10,1908 andc=3,6004Å. The cell content is 2 formula units, the space group is C 4h 5 −I4/m.
    Notes: Zusammenfassung Die Struktur von Nb5Cu4Si4 wird mit Hilfe von Einkristallmethoden bestimmt und verfeinert. Die Abmessungen der tetragonalen, innenzentrierten Elementarzelle sind:a=10,1908 undc=3,6004 Å. Die Zelle beinhaltet 2 Formeleinheiten, die Raumgruppe ist C 4h 5 −I4/m.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00901203
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