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  • 1
    Electronic Resource
    Electronic Resource
    A Case of Paracoccidioidomycosis: Experience with Long-Term Therapy (2000)
    Springer
    Infection 28 (2000), S. 119-120 
    Details
    ISSN: 1439-0973
    Keywords: Key words Paracoccidioidomycosis ; Therapy of paracoccidioidomycosis ; Mycosis ; Osteolysis ; Itraconazole
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We describe long-term therapy for paracoccidioidomycosis occurring in a 61-year-old housepainter from Venezuela. The diagnostic examinations made in South America had shown pulmonary granulomatous lesions and an osteolytic pattern of the left knee that had been considered suspect of malignant disease with an indication for limb amputation. With the aid of fine needle aspiration biopsy (FNAB) and culture examination we diagnosed an osteomyelitis by Paracoccidioides brasiliensis and initiated therapy with itraconazole, 400 mg per day reduced to 200 mg per day after 2 months. At the end of 2 years of drug therapy, we observed complete regression of the pulmonary lesions and of the osteolytic area of the left knee. Moreover, we have periodically observed our patient to verify his clinical development and he is still in good health. We suggest that this pathology be considered in differential diagnosis of leprosy, tuberculosis, leishmaniasis, and systemic mycoses, even in non-endemic areas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s150100050060
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  • 2
    Electronic Resource
    Electronic Resource
    The relation between polyphenoloxidase activity and ability to produce indoleacetic acid in Fusarium-infected tomato plants (1968)
    Springer
    European journal of plant pathology 74 (1968), S. 47-51 
    Details
    ISSN: 1573-8469
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Description / Table of Contents: Samenvatting Ten aanzien van extracten van gezonde en metFusarium oxysporum f.lycopersici geïnoculeerde tomateplanten werd een rechtlijnig verband gevonden tussen de polyfenoloxydase activiteit en de snelheid, waarmee indolylazijnzuur (IAA) in aanwezigheid van chlorogeenzuur uit tryptofaan werd gevormd. Zowel polyfenoloxydase activiteit als productie van IAA waren enigermate geringer na dialyse van gezuiverde en ruwe extracten. De werking van polyfenoloxydase en de vorming van IAA werden gedeeltelijk geremd door DIECA, EDTA, cysteine en ascorbinezuur. Dit gold voor ruwe en gezuiverde extracten en stukjes stengel van gezonde zowel als van zieke planten. Het effect was echter steeds groter in materiaal afkomstig van geïnoculeerde planten. De verkregen resultaten kunnen beschouwd worden als een bevestiging van de nauwe relatie tussen polyfenoloxydase activiteit en IAA productie in tomateplanten. Op het verschil in gevoeligheid voor remstoffen tussen materiaal afkomstig van zieke en van gezonde planten wordt speciaal de aandacht gevestigd.
    Notes: Abstract Different protein fractions precipitated with ammonium sulphate from extracts of healthy andFusarium-infected tomato plants showed a linear relationship between polyphenoloxidase activity and ability to form indoleacetic acid (IAA) from tryptophan in the presence of chlorogenic acid. Dialysis slightly reduced polyphenoloxidase activity of as well as IAA formation by crude and purified extracts. Polyphenoloxidase as well as IAA production were partially inhibited by DIECA, EDTA, cystein and ascorbic acid. The inhibition was shown to occur in crude and purified extracts and stem slices of both healthy and diseased plants, but was consistently higher in material from diseased plants. The reported results may be considered to further confirm the strict interdependence between polyphenoloxidase activity and ability to form IAA in tomato plants. The different sensitivity to some inhibitors shown by material from healthy and from diseased plants is emphasized.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01977512
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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