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  • 1
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Immunological reviews 112 (1989), S. 0 
    ISSN: 1600-065X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of medicinal chemistry 13 (1970), S. 211-213 
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 43 (1984), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Antibodies were raised against the 200-kd, 145-kd, and 68-kd subunits of a rat neurofilament preparation. Immunoblots showed that each antibody was specific for its antigen and that it did not cross-react with any of the two other neurofilament polypeptides. Use of the three antibody preparations to stain bovine chromaffin cells in culture by the indirect immunofluorescence technique indicated that the three neurofilament polypeptides are present in chromaffin cells maintained in culture for 3 or 7 days. The three anti-neurofilament antibodies labelled the cells in a similar pattern: very thin filaments specifically localized around the nucleus were observed whereas neurites and growth cones, developed by cultured chromaffin cells, were generally not stained. Some fibroblasts were present in our cultures but they were never stained by any of the neurofilament antibodies. This indicated that the antibodies used do not react with vimentin, the major intermediate filament protein found in fibroblasts. The three neurofilament antibodies were also used to immunoprecipitate specifically three proteins of molecular weights 210 kd, 160 kd, 70 kd from solubilized extracts of cultured chromaffin cells that were radiolabelled with [35S]methionine. These proteins correspond in molecular weight to the neurofilament triplet found in bovine brain. Finally, the presence of neurofilaments in freshly isolated chromaffin cells was tested by immunoblotting using the 68-kd antibody. A 70-kd protein was specifically stained by this antibody, suggesting that neurofilaments are not only present in cultured chromaffin cells but also in the adrenal gland in vivo. It is concluded from these results that chromaffin cells contain completely assembled neurofilaments. This additional neuronal property again illustrates that chromaffin cells are closely related to neurons and therefore represent an attractive model system for the study of functional aspects of adrenergic neurons.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd
    Sedimentology 45 (1998), S. 0 
    ISSN: 1365-3091
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: A detailed analysis of sedimentary organic matter (or palynofacies) was carried out on thermally immature to early mature Upper Jurassic and Hauterivian condensed intervals in deep-sea carbonate–marl alternations outcropping in the Vocontian Basin (SE France). All the condensed sections studied are characterized by intense bioturbation and very low organic carbon content (〈 0·25 wt.%), indicative of oxic depositional conditions.Oxic condensed sections display variable palynofacies signatures, which are best illustrated by: (1) the ratio of continental to marine constituents; (2) the ratio of opaque to translucent phytoclasts (i.e. woody debris) and (3) the preservation of palynomorphs (based on fluorescence intensity and morphological preservation state in transmitted light microscopy). Both of the ratios increase with the degree of palynomorph degradation, which shows that phytoclasts, especially the opaque ones, become relatively concentrated in the most degraded facies. These observations lead to the classification of oxic condensed sections into three organic facies types showing different degrees of preservation and palynofacies signatures. Type 1 organic facies display intense degradation and are characterized by high values of the ratio of continental to marine fraction. They record unfavourable depositional environments for preservation of organic matter. Type 2 organic facies are most common and are characterized by a decreasing value of the ratio of continental to marine fraction. Type 3 organic facies display the same trend of the ratio of continental to marine fraction as type 2, but the palynomorph assemblage is better preserved. Type 1 and type 3 organic facies are relatively rare.Recognizing these organic facies types is important when analysing the relationship between sedimentary organic matter and sequence stratigraphy, because it allows the use of the appropriate palynofacies parameters. In particular, the use of the ratio of continental to marine constituents, usually a very good indicator of regressive–transgressive trends, becomes questionable in highly degraded intervals. Moreover, distinguishing between well-preserved or highly degraded palynofacies in condensed intervals provides valuable information on the oxicity of the depositional environment.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Sedimentology 44 (1997), S. 0 
    ISSN: 1365-3091
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Outcrop sections from the Swiss Jura, consisting of carbonate-siliciclastic deposits spanning the Middle-Late Oxfordian boundary, provide a palaeogeographical cross-section ranging from coastal to shallow platform and intra-platform basin environments. Using a sedimentological and a 3rd order sequence stratigraphic framework based on those sections, the distribution of sedimentary organic matter (palynofacies) has been spatially studied in relation to sequence stratigraphy.The main factors influencing the spatial variations of sedimentary organic matter are the proximity of land, organic productivity, level of biodegradation and hydrodynamic conditions of the palaeoenvironment. These factors determine the distribution of the land-derived, relatively allochthonous organic constituents (phytoclasts, pollen and spores), and marine, relatively autochthonous constituents (phytoplankton and foraminifera linings).Five main palynofacies parameters appear as good indicators of proximal-distal trends: the relative proportion of total phytoclasts; the proportion of fresh, translucent fragments among these phytoclasts; the ratio of marine to continental palynomorphs; and the relative amount and species diversity of dinoflagellate cysts. In lowstand deposits, high-energy hydrodynamic conditions may affect these trends on the shallow platform, where storms tend to increase the proportion of the marine organic fraction landwards. These five palynofacies parameters are largely related to water depth. Therefore, when compared with the established 3rd order sequence stratigraphic framework, their stratigraphic variations indicate relative sea-level changes or, alternatively, proximality changes. Parameters indicative of more distal conditions increase in the transgressive and early highstand, and decrease in the late highstand. The opposite occurs for parameters indicative of more proximal conditions. Foraminifera linings seem to be particularly concentrated near the shelf edge and on the slope. Finally, bisaccate pollen may display cyclicity associated with alternating humid and dry periods. This palaeoclimatic signature may be related to orbital cyclicity.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 0301-0104
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 254 (1975), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 207 (1973), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 247 (1974), S. 104-106 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Antigen binding, with detection of immunoglobulin or 6 surface markers on the same cell, has been described9. Briefly, 20 x 106 spleen or lymph node cells were mixed with various amounts of 125I-TIGAL (20 to 300 jttCi fjLg~l) in a final volume of 0.4 ml ice cold Eagle's Minimal Essential Medium, ...
    Type of Medium: Electronic Resource
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