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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 139 (1982), S. 87-89 
    ISSN: 1432-1076
    Keywords: Chromosome 21 ; Tetrasomy ; Translocation ; Mosaicism ; Malformations ; Isochromosome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 5-year-old boy with severe mental handicap, dysmorphic stigmata and a tetrasomy 21 in fibroblasts is reported. Blood lymphocytes of the patient have a normal karyotype. The origin of this tetrasomy 21 mosaicism is discussed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1459
    Keywords: Multiple sclerosis ; Cognitive functioning ; MRI Neuropsychology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The relationship between cognitive impairment in multiple sclerosis and brain lesions seen on magnetic resonance imaging (MRI) was studied. Three groups of 11 patients with multiple sclerosis, matched for the variables of disability, duration of illness, age and sex, were included. On the basis of neuropsychological testing, the groups were seen to differ in their level of cognitive impairment. The first group showed no cognitive impairment, the second group a moderate, and the third group a serious cognitive impairment. These differences between the groups were reflected by MRI, which revealed more abnormalities in the groups with cognitive impairment compared with the group with normal cognitive function. However, by MRI it was not possible to distinguish between the groups with moderate and that with serious cognitive impairment.
    Type of Medium: Electronic Resource
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