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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 7 (1992), S. 177-183 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Des polypes gastriques et duodénaux sont fréquemment rencontrés au cours de la polypose adénomateuse familiale. La transformation cancéreuse de ces polypes peut être une importante cause de décès chez les malades qui ont eu des résections coliques. Le but de cette étude est de déterminer la nature et la distribution des polypes de cette région chez les patients chinois. 25 patients atteints de polypose adénomateuse familiale ont été gastroscopés par un même opérateur utilisant un système de vidéoendoscopie à vue terminale. Des biopsies représentatives de la muqueuse normale ou de polypes existants ont été réalisées au niveau du fundus de l'antre et du duodénum. 25 malades ont été étudiés, 17 hommes, 8 femmes d'un âge moyen de 32 ans (17–63 ans). 19 patients avaient des polypes macroscopiquement visibles dans le tube digestif supérieur. 10 malades avaient des polypes gastriques seuls, 3 avaient des polypes duodénaux seuls tandis que 6 avaient à la fois des polypes gastriques et duodénaux. 12, 1 et 3 patients avaient plus de 20 polypes dans le fundus, l'antre ou le duodénum respectivement. 1 seul malade avait des polypes d'un diamètre supérieur à 10 mm. Le type le plus common de polype du fundus était un polype des glandes fundiques tandis que des polypes hyperplasiques et adénomateux étaient les polypes les plus communs dans l'antre et dans le duodénum respectivement. 5 malades avaient des polypes adénomateux dont 4 avaient uniquement des adénomes duodénaux tandis que 1 patient avait des adénomes duodénaux, gastriques au niveau de l'antre et du fundus. 76% de nos patients avec une polypose adénomateuse familiale avaient une polypose au niveau du tube digestif supérieur. Les polypes adénomateux ont été trouvés chez 56% des malades avec des polypes duodénaux ou 20% des malades ayant des polypes du tube digestif supérieur mais les polypes hyperplasique et hamartomateux surviennent fréquemment chez les patients qui ont une polypose adénomateuse familiale.
    Notes: Abstract Polyps in the stomach and duodenum are frequently found in familial adenomatous polyposis. Cancer arising from some of these polyps may be an important cause of death in patients who have had large bowel resections. This study aims to determine the nature and distribution of foregut polyps in Chinese patients. Twenty-five patients with familial adenomatous polyposis were gastroscoped by a single operator using the end viewing video-endoscopy system. Representative biopsies of normal mucosa or polyps where appropriate were taken from the gastric fundus, antrum and the duodenum. Twenty-five patients were studied. Male=17, female=8. Median age was 32 years (range=17–63 yrs). Nineteen patients were found to have macroscopically visible polyps in the foregut. Ten patients had gastric polyps alone, three patients had duodenal polyps alone whilst six patients had both gastric and duodenal polyps. Twelve, one and three patients had more than 20 polyps in the gastric fundus, antrum and duodenum respectively. Only one patient had polyps which were larger than 10 mm. The commonest polyp in the gastric fundus was the fundic gland polyp whilst hyperplastic and adenomatous polyps were the commonest polyps in the gastric antrum and duodenum respectively. Five patients had adenomatous polyps of which four had duodenal adenomas alone whilst one patient had adenomas in the duodenum, gastric antrum and fundus. Seventy-six per cent of our patients with familial adenomatous polyposis had foregut polyposis. Adenomatous polyps were found in 56% of patients with duodenal polyps or 20% of patients with foregut polyps but hyperplastic and hamartomatous polyps occur commonly in patients with familial adenomatous polyposis as well.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 8 (1993), S. 170-174 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les conséquences cliniques et physiologiques de la conservation sphinctérienne après résection d'un cancer du rectum à des hauteurs variables ont été évaluées. 32 patients (âge moyen 59,2 ans, extrême 31–79 ans) qui avaient subi une chirurgie curatrice au moins un an auparavant sans thérapie adjuvante, ont été étudiés avec 19 contrôles normaux. 3 observateurs anonymes ont étudié indépendament les fonctions cliniques du sphincter, la hauteur de l'anastomose (ANL) et la manométrie anorectale. 85,7% des patients avaient une augmentation de la fréquence des selles mais leur mode de vie normale n'était pas affecté. La fréquence moyenne des selles était de 3,1 (2–8) fois par jour. La pression basale anale maximale et la pression maximum de retenue, le volume rectal de première sensation (VIS) et besoin, le volume maximum tolérable et la compliance étaient tous significativement altérés (P〈0,05). Les patients avec les plus mauvaises fonctions avaient significativement les plus bas ANL (P〈0,05). Sur l'analyse de la regression multiple, l'ANL et le VIS prédisaient de façon significative la fréquence des selles (P〈0,05). L'ANL au dessous de 6 cm était associée de façon significative avec une fréquence altérée des selles (P〈0,05). Ceci peut être un sous groupe de patients dont la fonction résiduelle de réservoir rectal est compromise et peut théoriquement bénéficier de poches coliques.
    Notes: Abstract The clinical and physiological consequences of sphincter preservation after resection of rectal carcinoma at various levels were evaluated. Thirty-two patients (mean age 59.2 years; range 31–79 years) who had undergone curative surgery at least one year previously and were not given adjuvant therapy, were studied with 19 normal controls. Three blinded observers independently assessed clinical sphincter function, level of anastomosis (ANL) and anorectal manometry. 85.7% had an increase in stool frequency but their normal lifestyles were unaffected. The mean stool frequency was 3.1 (range 2 to 8) times/day. The anal maximal basal and maximum squeeze pressures, rectal volume of first sensation (VIS) and unge, maximum tolerable volume and compliance were all significantly impaired (P〈0.05). Patients with poorer function had significantly lower ANLs (P〈0.05). On multiple regression analysis, the ANL and the VIS significantly predicted stool frequency (P〈0.05). ANL below 6 cm was significantly associated with impaired frequency of stools (P〈0.05). This may be a subgroup of patients whose residual rectal reservoir function is compromised and may theoretically benefit from colonic pouches.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 8 (1993), S. 193-196 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé 34 (4,1%) de 820 patients opérés de cancer colorectaux entre avril 89 et octobre 92 avaient des cancers synchrones. 20 (59%) étaient des hommes et 14 (41%) des femmes. L'âge moyen était de 69, 3 ans (25–89 ans). Les tumeurs synchrones étaient localisées dans le même segment ou les segments voisins du colon chez 24 (71%) des malades. Une résection curative a été réalisée chez 27 (79%) des patients, une résection palliative chez 8 (18%) et un malade (3%) a eu seulement une colostomie palliative. Le stade de Dukes du cancer le plus évolué des 2 montrait 1 (3%) Dukes A, 11 (32%) Dukes B, 14 (38%) Dukes C, et 9 (27%) avec une maladie disséminée. L'âge, le sexe et le stade de Dukes ne différaient pas significativement de ceux des patients qui avaient un cancer unique et le pronostic n'était pas pire.
    Notes: Abstract Thirty-four (4.1%) out of 820 patients operated for colorectal cancer between April 1989 and October 1992 were found to have synchronous cancers. Twenty (59%) were male and 14 (41%) were female. The mean age was 69.3 years (range=25 to 89 yr). Synchronous tumours were located in the same or adjacent segments of the large intestine in 24 (71%) of the patients. A curative resection was performed in 27 (79%) patients, a palliative resection in 8 (18%) and one (3%) patient had a palliative colostomy only. Dukes' staging based on the worse of the 2 cancers showed 1 (3%) Dukes' A, 11 (32%) Dukes' B, 14 (38%) Dukes' C and 9 (27%) with disseminated disease. Age, sex and Dukes' staging did not differ significantly from those of patients with solitary cancers and prognosis was also not adversely affected.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 8 (1993), S. 210-212 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé 4 cas parmi 204 nouveaux cas de cancers colorectaux vus dans une période de 24 mois, montraient une colite ischémique proximale concomitante. La colite ischémique associée avec un cancer colorectal ischémique, peut se présenter dramatiquement avec gangrene et perforation colique si l'insuffisance vasculaire aigue est sévère. Les lésions moins sévères d'ischémie doivent être reconnues au cours de l'intervention car une anastomose colique sur un colon ischémique peut provoquer un lâchage anastomotique. Deux autres patients avec des colites ischémiques furent faussement diagnostiqués comme cancer colorectal à la coloscopie. Les aspects endoscopiques de la colite ischémique peuvent simuler le cancer colique et les biopsies endoscopiques sont essentielles si le moindre doute existe quant à la possibilité de colite ischémique afin qu'une chirurgie inutile soit évitée.
    Notes: Abstract Four cases out of 204 new cases of colorectal carcinoma seen in a 24 month period were proven to have concomitant proximal ischaemic colitis. Ischaemic colitis associated with obstructing carcinoma of the colorectum may present dramatically with gangrene or colonic perforation if the acute vascular insufficiency is severe. Less severe degrees of ischaemic insult must be recognised intra-operatively as the incorporation of ischaemic colon in a colonic anastomosis may result in an anastomotic leak. Two other patients with ischaemic colitis were wrongly diagnosed as colorectal carcinoma on colonoscopy. Endoscopic features of ischaemic colitis may mimic colonic carcinoma and endoscopic biopsy is essential where any doubt exist as to the possibility of ischaemic colitis so that unnecessary surgery may be avoided.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The DNA content of 203 cases of rectal cancer, with at least 15 years follow-up, was analysed by flow cytometry. One hundred and twenty-nine (64%) were DNA aneuploid and corrected survivals were significantly influenced by ploidy distribution (p 〈 0.01). The DNA content and details of stage and grade were subjected to multivariate analysis using the Cox regression model. Ploidy was entered into models including Dukes' stage alone, tumour differentiation alone, Dukes' stage and differentiation in combination and a more comprehensive range of discrete stage- and grade-related parameters. All four models demonstrated its independent contribution to survival. However, its contribution was very small (5%, 18%, 5%, 4% respectively). These findings illustrate that results based on new technological developments should not be viewed in isolation, but their values must be assessed in combination with traditionally available data by means of multivariate analysis.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 6 (1991), S. 212-213 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Six cas de douleurs aigues anales duent à l'impaction dans le canal anal d'os ingérés sont rapportés. Le tableau clinique simule les causes communes de douleurs anales aigues telles que abcés péri-anal, fissures ou hémorroïdes thrombosées. Le diagnostic est facilement fait sur un simple toucher rectal. L'ablation rapide de l'os provoque un soulagement immédiat de la douleur tandis qu'un retard de diagnostic peut entraîner une pénétration plus profonde de l'os et la formation d'un abcés.
    Notes: Abstract Six cases of acute anal pain due to impaction of ingested bone in the anal canal are reported. The clinical presentation mimicks common causes of acute anal pain such as perianal abscesses, fissures or thrombosed haemorrhoids. The diagnosis is readily made on simple digital rectal examination. Early removal of the bone results in immediate pain relief, whilst delayed diagnosis may result in deeper penetration of the bone and abscess formation.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 8 (1993), S. 139-141 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Pour la qualité des contrôles, un système de vérification computérisée pour colonoscopie a été developpé dans le départment de chirurgie colorectale de l'hôpital Général de Singapour. La première année d'expérience a été revue pour déterminer la charge de travail et les performances individuelles des opérateurs. Les taux de satisfaction colonoscopique, à la fois faits bruts et transformation cusum ont été utilisés comme indices de contrôle de qualité. Le taux moyen de satisfaction colonoscopique dans l'unité était de 97% et quant les tendances temporelles ont été utilisées par CUSUM tous les opérateurs ont atteints de façon constante ou dépassé le taux seuil minimum de satisfaction de 90%.
    Notes: Abstract For quality control purposes, a computer based auditing system for colonoscopy has been developed in the Department of Colorectal Surgery, Singapore General Hospital, Singapore. The first year's experience was reviewed to determine both workload patterns and the individual operators' performances. Colonoscopic completion rates, both as raw data and cusum transformations, were used as indices of quality control. The mean colonoscopic completion rate for the Unit was 97.0% and, when temporal trends were analysed by cusum, all operators consistently met or exceeded the minimum target completion rate of 90%.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 10 (1995), S. 107-111 
    ISSN: 1432-1262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La mise en évidence d'une relation linéaire entre la descente périnéale (PD) et le temps de latence du nerf honteux interne (PNMTL) est importante dans la compréhension de la physiopathologie d'une neuropathie du nerf honteux. La mesure de l'étirement du nerf honteux résultant d'une augmentation de la descente du périnée doit corréler avec l'importance de l'atteinte nerveuse (PNMTL). Les deux études clé précédentes qui utilisaient différentes techniques de mesure du périnée descendant étaient divergentes quant à cette conclusion essentielle. Une étude prospective a été entreprise sur 141 patients consécutifs avec un périnée descendant afin d'éclaircir cette divergence (M:F=57:84; age moyen 46.3 en ±1,6). Les patients souffraient de constipation chronique (81), d'incontinence fécale neurogénique (31), de prolapsus muqueux rectal (17) ou d'incontinence urinaire de stress chez la femme (9). Dans tous les cas, on a réalisé une mesure du périnée descendant par périnéométrie, des mesures des pressions sphinctériennes, une électromyographie à fibre unique des sphincters et une mesure du temps de latence du nerf honteux interne. Ces variables de même que l'âge ont été étudiés par une analyse à régression multiple afin de mettre en évidence une relation linéaire avec le périnée descendant. L'âge est la seule variable indépendante qui prédise un périnée descendant au repos (T=3,2, P〈0.005). Le temps de latence du nerf honteux interne était la seule variable prédisant le périnée descendant à l'effort (T=3.0, P〈0.005). En conclusion, nous pouvons confirmer une relation linéaire entre le périnée descendant, l'effort d'exonération et le temps de latence du nerf honteux interne confirmant en cela une étude antérieure qui confirme également le périnée descendant par périnéométrie. L'autre étude qui réfutait une telle relation n'était établie que sur une mesure radiologique du périnée descendant, aussi est-il probable que la différence résulte de la technique de mensurations.
    Notes: Abstract The establishment of a linear relationship between perineal descent (PD) and pudendal nerve motor terminal latency (PNMTL) is important in understanding the pathophysiology of pudendal neuropathy. The amount of stretching of the pudendal nerve resulting from the extent of PD, should correlate with the amount of injury sustained (PNMTL). The two key previous studies which used different techniques to measure PD, have differed on this vital issue. A prospective study was undertaken in 141 consecutive patients with PD (M:F=57:84; mean age 46.3 SEM 1.6 years) to clarify this discrepancy. The patients had chronic constipation (81), neurogenic faecal incontinence (31), rectal mucosal prolapse (17) or female urinary stress incontinence (9). All underwent measurements of PD (by perineometry), anal sphincter pressures, single fibre anal sphincter electromyography and PNMTL. These variables, as well as age were analyzed for a linear relationship with PD by multiple regression analysis. Age was the only independent variable predicting PD at rest (T=-3.2; p〈0.005). PNMTL was the only independent variable predicting PD on straining (T=-3.0; p〈0.005). In conclusion, a linear relationship between PD on straining and PNMTL was confirmed, supporting the previous study which also measured PD by perineometry. The other study which refuted such a relationship measured PD radiologically, and it is likely that the difference was in the measurement technique.
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Diseases of the colon & rectum 37 (1994), S. 1130-1132 
    ISSN: 1530-0358
    Keywords: Anal fissure ; Anorectal surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: A study was conducted to compare the outcome of combined anorectal procedures involving lateral internal sphincterotomy with lateral internal sphincterotomy alone to determine if the former results in increased complications. METHODS: Complications and anal function of 57 patients who underwent lateral internal sphincterotomy for chronic anal fissure in conjunction with another anorectal procedure (combined group) between April 1989 and June 1992 were compared with 57 other age- and sex-matched patients who underwent lateral internal sphincterotomy alone (control group). RESULTS: There was no statistical difference in the incidence of incontinence in the combined group (8.7 percent) and the control group (7 percent). None of the cases in either group had permanent incontinence. There were also no statistical differences in the incidence of postoperative bleeding, pruritus ani, mucus discharge, abscess formation, fistulation, and rates of fissure recurrence. CONCLUSIONS: Additional anorectal procedures performed at the same time as internal sphincterotomy do not increase the incidence of postoperative complications.
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Diseases of the colon & rectum 38 (1995), S. 239-244 
    ISSN: 1530-0358
    Keywords: Anal canal sensation ; Mucosal electrosensitivity ; Sensory threshold
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: Anal electrosensation is usually tested by an annular configured electrode that stimulates the circumference of the anus. In certain pelvic conditions, the right and left pudendal nerve function may be damaged separately and to different degrees. This may only be detected by a unilateral electrode testing each side independently. METHODS: Our study compares accuracy and sensitivity of annular and unilateral electrodes in assessing patients with hemorrhoids, perineal descent, incontinence, after low anterior resection, and constipation (107 subjects). RESULTS: In normal controls (n=19), annular thresholds ranged from 0.5 to 2.7 mA and unilateral thresholds from 0.6 to 2.6 mA. In prolapsed hemorrhoids, unilateral was more sensitive than annular electrode in detecting deficits at the upper (P 〈0.0001), mid (P 〈0.005), and lower (P 〈0.0005) anus. Patients with perineal descent had a sensory deficit in the upper anal canal, detected more consistently by unilateral electrode (P 〉0.05). No significant abnormalities were found in neuropathic incontinence, after anterior resection and chronic constipation. Results of the unilateral electrosensory technique were found to be consistent with repeated measurements (r =0.8878; P 〈0.001). CONCLUSIONS: By being more sensitive than the annular technique, the unilateral electrode method may become, with refinement, a useful test for quantifying anal sensation.
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