ISSN:
0947-3440
Keywords:
Pyridinium ylides
;
(Arylmethylene)isoxazol-5-ones
;
Michael addition
;
Sterically congested molecules
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The reactions of (arylmethylene)isoxazol-5-ones 1 with pyridinium ylides 2 lead to the diastereoselective formation of olates 4. The reasons for the favored Michael addition and the unsuccessful subsequent cyclization to fused O-heterocycles are discussed on the basis of X-ray analysis as well as 1H-NMR and chemical evidences.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.199719970224
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