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  • 1
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    Lifeboats, steam (1890)
    London : Periodicals Archive Online (PAO)
    RSA Journal. 39 (1890:Nov. 14-1891:Nov. 13) 127 
    Details
    ISSN: 0958-0433
    Topics: Art History
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:q549-1890-039-00-000539
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  • 2
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    6th Meeting: - "Steam lifeboats" (1890)
    London : Periodicals Archive Online (PAO)
    RSA Journal. 39 (1890:Nov. 14-1891:Nov. 13) 127 
    Details
    ISSN: 0958-0433
    Topics: Art History
    Description / Table of Contents: ORDINARY
    Notes: MEETINGS OF THE 137TH SESSION
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:q549-1890-039-00-000601
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  • 3
    Electronic Resource
    Electronic Resource
    Interaction of Vagal Lung Afferents with Inhalation of Histamine Aerosol in Anesthetized Dogs (2000)
    Springer
    Lung 178 (2000), S. 41-52 
    Details
    ISSN: 1432-1750
    Keywords: Key words: Histamine—C-fibers—Rapidly adapting pulmonary stretch receptors—Pulmonary defense reflex—Capsaicin.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. In seven alpha-chloralose anesthetized dogs we examined the contribution of lung afferents to the rapid, shallow breathing induced by inhalation of 10 breaths of histamine aerosol. In four spontaneously breathing dogs, the inhalation of histamine caused an increased respiratory frequency, decreased tidal volume, and decreased dynamic lung compliance. Selective blockade of pulmonary C-fibers abolished a reflex-induced increase in respiratory frequency but did not significantly affect the reductions in tidal volume or lung compliance. Terbutaline treatment in combination with C-fiber blockade abolished the reductions in tidal volume and lung compliance induced by histamine. In three separate alpha-chloralose anesthetized, open-chest, mechanically ventilated dogs, we recorded an increase in the inspiratory activity of rapidly adapting pulmonary stretch receptors (RARs) induced by the inhalation of histamine aerosol. Selective C-fiber blockade abolished histamine-induced increases in RAR activity while only partially attenuating reductions in lung compliance. We conclude that the increase in RAR activity induced by histamine depends on intact C-fibers and not on a direct effect of histamine on RARs or an indirect effect of histamine reducing lung compliance. In addition, our data illustrate the multiple interactions that occur between the various vagal afferents and their roles in the reflexes induced by histamine inhalation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004080000005
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  • 4
    Electronic Resource
    Electronic Resource
    The effects of haloperidol on visual search, eye movements and psychomotor performance (1997)
    Springer
    Psychopharmacology 133 (1997), S. 233-239 
    Details
    ISSN: 1432-2072
    Keywords: Key words Haloperidol ; Lorazepam ; Saccadic eye movements ; Smooth pursuit eye movements ; Visual search ; Psychomotor tests
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of single doses of haloperidol (2, 4 and 6 mg) were compared with lorazepam 2.5 mg and placebo in 15 healthy subjects. Visual search strategy was measured, along with a range of psychomotor and eye movement tests. Patients with Parkinson’s disease have been shown to exhibit a shift from parallel to serial processing in visual search, but we demonstrated that this does not occur following administration of either haloperidol or lorazepam. Haloperidol was detected by visual analogue rating scales and peak saccadic velocity, the latter being the more sensitive measure. Haloperidol had no statistically significant effect on smooth pursuit position error, velocity error or saccadic intrusions. Digit symbol substitution performance was clearly diminished by haloperidol, but there was no effect on the continuous attention test. Lorazepam decreased performance in all tests apart from saccadic latency.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002130050396
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  • 5
    Electronic Resource
    Electronic Resource
    A comparison of the sedative and amnestic effects of chlorpromazine and lorazepam (1996)
    Springer
    Psychopharmacology 128 (1996), S. 67-73 
    Details
    ISSN: 1432-2072
    Keywords: Key words Neuroleptics ; Chlorpromazine ; Lorazepam ; Saccadic eye movements ; Memory ; Sedation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of single doses of chlorpromazine (100mg) and lorazepam (0.5, 1 and 2mg) were compared with placebo in a battery of tests of information processing, working and semantic memory. Peak saccadic velocity was used to provide a precise and reliable measure of sedation and its results were found to be consistent with those using visual analogue rating scales. Chlorpromazine 100 mg was equally sedative to lorazepam 2 mg. Lorazepam caused dose-dependent deterioration in performance in many of the memory tests, whereas an equally sedative dose of chlorpromazine did not. These data therefore support the view that benzodiazepine-induced amnesia is not secondary to sedation. Peak saccadic velocity has considerable advantages over visual analogue scales as a measure of sedation, since it is objective and has a demonstrated low coefficient of variation. It is suggested that saccadic eye movement measurement will permit considerably more reliable and precise separation of the sedative and amnestic effects of drugs and will allow investigation of amnesia caused by clinically relevant doses of psychotropic drugs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002130050111
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  • 6
    Electronic Resource
    Electronic Resource
    Aporphines: 25 - Trimethylsilyl derivatives of N-methyl and N-propyl aporphines: Gas chromatographic and mass spectrometric properties (1979)
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 6 (1979), S. 282-286 
    Details
    ISSN: 0306-042X
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: A series of synthetic, semisynthetic and naturally occurring aporphine alkaloids were converted to the O-trimethylsilyl derivatives, and analyzed by gas chromatography mass spectrometry. A discussion of discussion of structurally informative fragment ions along with gas chromatographic data is presented. Their applicability to the analysis of biological metabolites of apomorphine, a CNS active structural analog of dopamine, is discussed.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/bms.1200060704
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